A5103191791- Tracheal and airway disorders
- Esophageal and GI Pathology
- Vascular Anomalies and Treatments
- Dysphagia Assessment and Management
- Gallbladder and Bile Duct Disorders
- Airway Management and Intubation Techniques
- Voice and Speech Disorders
- Esophageal Cancer Research and Treatment
- Soil Carbon and Nitrogen Dynamics
- Pancreatic and Hepatic Oncology Research
- Geoscience and Mining Technology
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Community Ecology and Physiology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Selenium in Biological Systems
- Coal Properties and Utilization
- Urological Disorders and Treatments
- Gastric Cancer Management and Outcomes
- Hydrocarbon exploration and reservoir analysis
- Head and Neck Surgical Oncology
- Gastroesophageal reflux and treatments
- Cancer-related molecular mechanisms research
- Foreign Body Medical Cases
- Ethics in Clinical Research
- Cancer Mechanisms and Therapy
First Affiliated Hospital of Zhengzhou University
2016-2025
Zhengzhou University
2013-2024
University of Arizona
2023
Institute of Subtropical Agriculture
2022-2023
University of Chinese Academy of Sciences
2022-2023
Yangtze University
2018-2022
Chinese Academy of Sciences
2018-2022
Research Center for Eco-Environmental Sciences
2018
Luohe Medical College
2016
Veterans Health Administration
2002
Recently, it has been shown that the exogenous addition of hydrogen peroxide (H(2)O(2)) increases endothelial nitric oxide (NO(.)) production. The current study is designed to determine whether endogenous levels H(2)O(2) are ever sufficient stimulate NO(.) production in intact cells. was detected by a NO(.)-specific microelectrode or an electron spin resonance spectroscopy using Fe(2+)-(DETC)(2) as trap. bovine aortic cells caused potent and dose-dependent increase release. Incubation with...
Recent studies have shown that long noncoding RNAs (lncRNAs) play pivotal roles in the initiation and progression of cancer, including esophageal squamous cell carcinoma (ESCC). The lncRNA HOX transcript antisense RNA (HOTAIR) was reported to be dysregulated correlated with ESCC. However, biological role underlying mechanism HOTAIR development ESCC remain unclear. Herein, we found aberrantly upregulated cells depletion inhibited proliferation led G1 cycle arrest cells. Besides, acted as an...
Personalized care models are dominating modern medicine. These rooted in teaching future physicians the skill set to keep up with innovation. In orthopedic surgery and neurosurgery, education is increasingly influenced by augmented reality, simulation, navigation, robotics, some cases, artificial intelligence. The postpandemic learning environment has also changed, emphasizing online skill- competency-based incorporating clinical bench-top research. Attempts improve work–life balance...
Thoracogastric airway fistula is a rare and serious complication post-esophageal cancer surgery with an incidence of about 0.2% to 1.9% [1]. Due the complexity these fistulas, endoscopic conservative treatments often fail. Most patients are too frail for surgery, making intervention-based closure therapy crucial treatment option [2] [3].
Grazing exclusion is one of the most common practices for degraded grassland restoration worldwide. Soil microorganisms are critical components in soil and play important roles maintaining ecosystem functions. However, changes bacterial community characteristics during grazing different types remain unclear. In this study, diversity composition as well co-occurrence patterns were investigated compared between (4 years) paired adjacent sites three temperate grasslands (desert steppe, typical...
The organic material amendment has been proven to change the soil antibiotic resistance genes (ARGs) profile, which may threaten human health through food chain, but effects and mechanisms of different materials on ARGs in paddy soils are less explored. In this study, a field experiment was set up with treatments conventional chemical fertilization (NPK) common [rice straw (RS), swine manure (SM), biochar (BC)] explore mechanisms. total, 84 unique were found across samples amendments, they...
miR-3940-5p level was lower in non-small cell lung cancer (NSCLC) tumor tissues than that the matched tumor-adjacent and correlated with clinicopathological features. Cyclin D1 (CCND1), a key driver of malignant transformation NSCLC, overexpressed many cancers, including NSCLC. The ubiquitin specific peptidase-28 (USP28) also NSCLC associated poor prognosis patients. We searched for targets by using TargetScan miRanda online tools found CCND1 USP28 were potential miR-3940-5p. Based on these...
Metal(loid)s can promote the spread and enrichment of antibiotic resistance genes (ARGs) in environment through a co-selection effect. However, it remains unclear whether exposure microorganisms to varying concentrations selenium (Se), an essential but potentially deleterious metal(loid) living organisms, influence migration distribution ARGs forest soils.Precisely 235 conferring seven classes antibiotics were detected along Se gradient (0.06-20.65 mg kg-1) across 24 soils....
Bronchopleural fistula (BPF) is an infrequent but life-threatening complication after pneumonectomy. The incidence of BPF reported in the literature varies from 0.3% to 20%.To determine feasibility and efficacy using Y-shaped, single-plugged, covered, metallic stents treat right bronchopleural fistulas.We have designed a self-expandable, airway stent fit specific anatomy main bronchus. has tube two branches, resembling inverted "Y". One branches closed (plugged) bullet-shaped; other one...
Primary succession of plant and microbial communities in the glacier retreating foreland has been extensively studied, but shifts antibiotic resistance genes (ARGs) with due to global warming remain elusive. Unraveling diversity features ARGs pristine soil during could contribute a mechanistic understanding evolution development resistome. In this study, we quantified abundance along 50-year chronosequence by using high-throughput quantitative PCR (HT-qPCR) technique. A total 24 two mobile...
Central airway stenosis is a condition that the diameter of trachea or main bronchus shrinkage caused by external compression internal tissue hyperplasia, which can cause difficulty breathing, asphyxia, and even death. Airway stenting an easy way to restore patency central airway, but stents commonly used in clinical practice lead complications such as mucus plugging, bacterial infection, granulation hyperplasia. Moreover, non-degradable characteristic makes it requires second operation...
Based on 3D printed models, the size, location, and morphology of thoracogastric airway fistulas can be more accurately assessed, which help physicians better determine size location stents or occluders [1].
Self.expandable metallic stent (SEMS) placement has been considered as the preferred treatment to relieve jaundice in nonsurgical patients. However, 50% of stents become stenosed within 3.6 months due tumor ingrowth and epithelial hyperplasia. This study aims evaluate feasibility efficacy a newly designed brachytherapy biliary drainage catheter (BBDC) loaded with 125I seeds for palliation malignant obstruction (MBO).In this prospective study, patients unresectable MBO underwent BBDC after...
Background Most patients with advanced pancreatic cancer do not have the chance to undergo surgery or chemotherapy because of their poor conditions. Biliary drainage is a palliative treatment restore liver function and alleviate jaundice, but most still face risk biliary obstruction in short term after operation. The purpose this study evaluate efficacy safety brachytherapy catheter (BDC)-combined complicated obstructive jaundice. Patients Methods From November 2017 May 2019, 48 underwent...
Abstract To compare stent-induced granulation tissue hyperplasia of bare (SEMS), polyurethane-covered (PU-SEMS) and electrospun nanofibre-covered (EN-SEMS) self-expandable metallic stents in the rabbit trachea. Twenty-seven rabbits were randomly assigned to 3 groups that received SEMS, PU-SEMS or EN-SEMS. Computed tomography sacrifice performed as scheduled. Haematoxylin–eosin Masson’s trichrome staining protocols for pathological analysis. The data tracheal ventilation area ratio,...
Bevacizumab loaded drug-eluting beads have the potential to reduce TACE related VEGF expression. The purpose of this study was investigate in vitro loading, and release profiles bevacizumab (BEV) on Callispheres (CB) its application rabbit liver VX2 tumor model.CB with sizes 100-300 um 300-500 were divided into 5 groups, respectively. BEV different content prepared for CB releasing detected solution at time points. diameters each group measured under a light microscope calculate shrinkage...
This study aims to investigate the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with Apatinib Camrelizumab for treating unresectable advanced gastric or gastroesophageal junction (G/GEJ) cancer.In this study, data patients G/GEJ cancer who received TACE from August 2018 December 2021 was evaluated. After TACE, were given intravenous 200mg every three weeks oral apatinib 250mg/day treatment. The primary endpoint overall survival (OS), secondary endpoints...
The application of esophageal stent closure fistulas is limited in to thoracogastric airway due changes anatomical structure after surgery. Additionally, the unique location three-branch orificium and large can cause complications such as displacement lax sealing [1] [2].