A5051683373- Asthma and respiratory diseases
- Vaccine Coverage and Hesitancy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cervical Cancer and HPV Research
- Obstructive Sleep Apnea Research
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Family and Disability Support Research
- Food Security and Health in Diverse Populations
- Innovations in Medical Education
- Healthcare Technology and Patient Monitoring
- Homelessness and Social Issues
- Pharmaceutical studies and practices
- Respiratory and Cough-Related Research
- Infant Development and Preterm Care
- Geriatric Care and Nursing Homes
- COVID-19 epidemiological studies
- Ethics and Legal Issues in Pediatric Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Childhood Cancer Survivors' Quality of Life
- Cystic Fibrosis Research Advances
- Patient Safety and Medication Errors
- Inhalation and Respiratory Drug Delivery
- Data-Driven Disease Surveillance
University of Cincinnati Medical Center
2018-2025
Cincinnati Children's Hospital Medical Center
2014-2025
University of Cincinnati
2021-2024
German Red Cross
2021-2022
Pulmonary Associates
2022
German Liver Foundation
2021-2022
Pediatrics and Genetics
2022
University of North Carolina at Chapel Hill
2013
INTRODUCTION: Evidence about specific carbohydrate diet (SCD) for inflammatory bowel disease (IBD) is limited. We conducted 54 single-subject, double-crossover N-of-1 trials comparing SCD with a modified (MSCD) and each the participant's baseline, usual (UD). METHODS: Across 19 sites, we recruited patients aged 7–18 years IBD active inflammation. Following 2-week baseline (UD), were randomized to 1 of 2 sequences 4 alternating 8-week MSCD periods. Outcomes included fecal calprotectin...
Children with chronic ventilator dependence are a complex and heterogeneous population unique needs. We sought input from parents, clinicians, hospital staff to identify opportunities for process improvement during hospitalization discharge preparation. conducted qualitative study at large referral center children dependence. Participants included parents of dependence, physicians, nurses, respiratory therapists, support staff. Two group-level assessment (GLA) sessions occurred, followed by...
Obstructive sleep apnea (OSA) in children alters circadian blood pressure (BP) rhythms. We hypothesised that BP dysregulation paediatric OSA is associated with structural and functional cardiac changes. This was a single-centre, cross-sectional, observational study of 5-14 years healthy controls. Participants underwent polysomnography, 24-h ambulatory monitoring, echocardiography. Circadian parameters included times arrived at velocity peaks nadirs, nocturnal dipping. Regression mediation...
Abstract Background The vision of learning healthcare systems (LHSs) is attractive as a more effective model for health care services, but achieving the complex. There limited literature describing processes needed to construct such multicomponent or assess development. Methods We used concept capability maturity matrix describe maturation necessary infrastructure and create networks (LNs), multisite collaborative LHSs that use an actor‐oriented network organizational architecture. developed...
Beneath top-down national and state directives recommendations, communities must respond to the many phases of coronavirus disease 2019 (COVID-19). The pandemic has unfolded differently across those with outcomes dependent on context, infrastructure, capacity, how assets are organized, linked, deployed. Achieving control requires real-time multisector data sharing, learning, adaptation. Leaders from health care, public health, congregate elected offices, neighborhoods, schools, businesses...
BACKGROUND AND OBJECTIVE: Short courses of antibiotics are often indicated for uncomplicated skin and soft tissue infections (uSSTIs). Our objective was to decrease duration prescribed in children hospitalized uSSTIs by using quality improvement (QI) methods. METHODS: QI methods were used upon hospital discharge uSSTIs. We sought accomplish this goal increasing outpatient prescriptions short therapy (≤7 days). Key drivers included awareness evidence among physicians, changing the culture...
Background10 The Joint Commission identified inpatient alarm reduction as an opportunity to improve patient safety; enhance patient, family and nursing satisfaction; optimise workflow. We used quality improvement (QI) methods safely decrease non-actionable notifications bedside providers. Methods In a paediatric tertiary care centre, we convened multidisciplinary team address in our acute cardiology unit. Alarm notification was defined any alert providers for each patient-triggered monitor...
Pediatric data on inpatient home insulin pumps are absent in the literature. Understanding safety of pumps, managed by patients or caregivers, during times illness will help diabetes technology securely move into pediatric hospitals.
Abstract Background Children with chronic medical conditions and their families have significant emotional health concerns, yet paediatricians are often ill‐equipped to address these needs. The American Board of Pediatrics launched the Roadmap Project better support as part routine care. We present pilot work in paediatric training programmes test educational approaches explore lessons learned. Approach Four institutions implemented tools into programmes, either incorporating them existing...
Inflammatory bowel disease (IBD) affects 3 million children and adults in the US. Treatment involves medications with considerable risk profiles. Dietary modification, such as specific carbohydrate diet (SCD), may be helpful treating IBD, but there is insufficient evidence of its effectiveness. N-of-1 trials are ideal for addressing this important research question. The Personalized Research on Diet Ulcerative Colitis Crohn's Disease (PRODUCE) study employs a series 50 individual that...
The goal of this study was to determine if parents' beliefs about social norms human papillomavirus (HPV) vaccination for sons were associated with knowledge HPV, intention vaccinate sons, or side effects. A cross-sectional, survey-based parents performed in 2010. Fisher's exact tests used examine associations between demographics and responses norms. Multivariate logistic regression models examined male HPV primary outcomes. Few agreed that others vaccinating (n = 31/267, 12%), including 1%...
Abstract Background Treatment regimens for cystic fibrosis (CF) continue to evolve and grow in complexity. regimen burden, associated sequelae, are incompletely understood. Objective Quality improvement (QI) methods were used investigate treatment burden of CF care, family care team partnerships, potential interventions reduce burden. Methods Patients 6–24 years with caregivers patients 6–13 surveyed. Portions validated tools existing surveys measured family‐care partnership. An automated...
Understanding factors that weigh heavily on Black patients and families during hospitalization is key to minimizing the strain of admission optimizing outcomes. Individuals with chronic conditions carry cumulative emotional burdens associated their illness into every hospitalization. additional burden trauma lived experiences structural racism. As part its strategic initiative mental health, American Board Pediatrics launched Roadmap Project an aim improve health in children youth...
Abstract Study Objectives Obstructive sleep apnea (OSA) adversely affects normal blood pressure (BP) and may disrupt circadian BP patterns. We sought to examine 24-hour rhythms in children with OSA healthy controls. Methods Children 5–14 years controls underwent monitoring actigraphy quantify sleep. Shape invariant statistical models compared patterns (e.g. times of peaks, time arrived at peak velocity [TAPV]) the control groups. Results The analytic sample included 219 (mild OSA: n = 52;...
Abstract Background To identify the determinants of health care use among homeless individuals. Methods Data were taken from Hamburg survey individuals ( n = 100 in here used model, mean age 44.8 years, SD 12.5) focusing on Hamburg, Germany. The number physician visits past 3 months and hospitalization preceding 12 as outcome measures. Drawing Andersen model a conceptual framework, predisposing characteristics, enabling resources need factors well psychosocial variables included correlates....
This study sought to determine if parents of males express concerns about vaccine-associated infertility (VAI) with the human papillomavirus (HPV) vaccine and understand impact those concerns.Parents sons were surveyed VAI concerns. Logistic regression was used find worried had lower knowledge HPV disease, more concern for side effects, lacked information vaccination, or intention vaccinate.In all, 39% VAI. Parents similar compared other parents. twice odds agreeing may cause effects they...
Abstract Objective Respiratory compromise in congenital muscular dystrophy (CMD) occurs, part, from chest wall contractures. Passive stretch with hyperinsufflation therapy could reduce related costo‐vertebral joint We sought to examine the impact of use on lung function and quality life children CMD. Study Design conducted a randomized controlled trial CMD at two centers. An individualized regimen 15 minutes twice daily using cough assist device over 12 months period was prescribed. measured...
Sharing data across institutions is critical to improving care for children who are using long-term mechanical ventilation (LTMV). Mechanical complex and poorly standardized. This lack of standardization a major barrier sharing.We aimed describe current ventilator in the electronic health record (EHR) propose framework standardizing these common model (CDM) multiple populations sites.We focused on cohort patients with LTMV dependence were weaned from (MV). We extracted described relevant EHR...
Surgical treatment of obstructive sleep apnea (OSA) in children requires knowledge upper airway dynamics, including the closing pressure (Pcrit), a measure collapsibility. We applied flow-structure interaction (FSI) computational model to estimate Pcrit patient-specific models obtained from magnetic resonance imaging (MRI) scans. sought examine agreement between measured and estimated FSI with Down syndrome. hypothesized that would accurately reflect during therefore severity OSA as by...
Shared decision making (SDM) between families and physicians may facilitate informed, timely decisions to proceed with biologic therapy in children inflammatory bowel disease (IBD). Our team previously developed an SDM tool aid communication when considering for IBD.We are conducting a prospective, pre-post pilot trial of new tool. The primary aim the study is assess feasibility both intervention procedures future large-scale trial.We enrolling experience prescribing past year IBD. Families...