A5031944225- Inflammatory Bowel Disease
- Microscopic Colitis
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Clostridium difficile and Clostridium perfringens research
- Dementia and Cognitive Impairment Research
- Diverticular Disease and Complications
- Adolescent and Pediatric Healthcare
- Celiac Disease Research and Management
- Geriatric Care and Nursing Homes
- Pancreatitis Pathology and Treatment
- Pharmaceutical studies and practices
- Childhood Cancer Survivors' Quality of Life
- Helicobacter pylori-related gastroenterology studies
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Neuroendocrine Tumor Research Advances
- Pediatric Pain Management Techniques
- Kidney Stones and Urolithiasis Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Gastroesophageal reflux and treatments
- Viral gastroenteritis research and epidemiology
- Intestinal Malrotation and Obstruction Disorders
Stanford University
2020-2025
Stanford Medicine
2022-2025
OsloMet – Oslo Metropolitan University
2020-2024
Lucile Packard Children's Hospital
2020-2024
Palo Alto University
2020-2023
Children's Mercy Hospital
2016-2022
Sawai ManSingh Medical College and Hospital
2014-2022
All India Institute of Medical Sciences Rishikesh
2022
All India Institute of Medical Sciences Jodhpur
2020
University of Missouri–Kansas City
2019-2020
The role of fecal microbiota transplant (FMT) in the treatment pediatric inflammatory bowel disease (IBD) is unknown. aims this study were to assess safety, clinical response, and gut microbiome alterations children with Crohn's (CD), ulcerative colitis (UC), or indeterminate (IC).In open-label, single-center prospective trial, patients IBD refractory medical therapy underwent a single FMT by upper lower endoscopy. Adverse events, microbiome, biomarkers assessed at baseline, 1 week, month, 6...
ABSTRACT Background Disseminated mycobacterium poses a significant risk for patients with NEMO deficiency. Hematopoietic stem cell transplant (HSCT) corrects the defect in hematopoietic cells thus treating immunodeficiency. Methods We present patient deficiency who successfully underwent HSCT despite disseminated Mycobacterium szulgai infection. Results Despite successful engraftment and resolution of infection, he developed inflammatory disease leading to his death. Conclusion does not cure...
Children with Crohn's disease (CD) may report abdominal pain despite clinical remission, suggesting that functional (FAP) be playing a role. The aim of this study was to explore the presence and impact FAP in children CD remission.Children, aged 9 17 years, were enrolled. Demographic information, Pediatric Disease Activity Index, Children's Depression Inventory obtained. remission defined by physician global assessment, normal laboratories findings, absence 3 or more stools day, nocturnal...
Peripheral neuropathies are a group of disorders which affect the peripheral nervous system have been conventionally diagnosed using electrodiagnostic studies. This study was carried out to assess role imaging in diagnosing mononeuropathy as exact anatomical localisation pathology is possible high-resolution ultrasound and MR neurography, modalities assessed this study.A hospital-based prospective analytical resource-limited setting on 180 nerves 131 patients with symptoms after taking IRB...
INTRODUCTION: Evidence about specific carbohydrate diet (SCD) for inflammatory bowel disease (IBD) is limited. We conducted 54 single-subject, double-crossover N-of-1 trials comparing SCD with a modified (MSCD) and each the participant's baseline, usual (UD). METHODS: Across 19 sites, we recruited patients aged 7–18 years IBD active inflammation. Following 2-week baseline (UD), were randomized to 1 of 2 sequences 4 alternating 8-week MSCD periods. Outcomes included fecal calprotectin...
Objectives: We sought to evaluate the safety and effectiveness of fecal microbiota transplantation (FMT) for recurrent Clostridioides difficile infection (CDI) in pediatric immunocompromised (IC) patients. Methods: This is a multicenter retrospective cohort study participants who underwent FMT between March 2013 April 2020 with 12-week follow-up. Pediatric patients were included if they met definition IC treated an indication CDI. excluded over 18 years age, those incomplete records,...
Introduction: Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) is an immune-mediated disease characterized by abrupt onset neurobehavioral changes. Inflammatory bowel (IBD) includes ulcerative colitis (UC) and Crohn’s (CD), chronic conditions gastrointestinal inflammation. We describe eight individuals with both PANS IBD. Methods: All IBD were identified from Stanford Immune Behavioral Health Clinic, Cedars-Sinai Medical Center Bowel Disease Program, Dartmouth Neuroimmune Psychiatric...
Abstract Inflammatory Bowel Disease (IBD) is a chronic inflammation of the gut, where symptoms are perceived to be influenced by diet. Avoidant/Restrictive Food Intake Disorder (ARFID) in IBD driven fear pain or diarrhea, sensory sensitivity lack interest eating. This can lead malnutrition and emotional distress, compromising overall health disease management. The prevalence ARFID general population considered 2-3% was found more common adult patients (10-17%); however, its occurrence...
Background/Objectives: In adolescent patients with ulcerative colitis refractory to anti-tumor necrosis factor (TNF) therapy, episodes of acute severe (ASUC) require hospitalization or surgery. Upadacitinib can be a potential colectomy-sparing agent in adult ASUC receiving intensified dosing. Methods: This case series evaluates clinical outcomes rescue upadacitinib dosing ASUC. We included adolescents admitted anti-TNF treated 30 mg twice daily upadacitinib. The primary outcome was the...
Abstract Background The incidence of very early onset inflammatory bowel disease (VEOIBD) is increasing, yet the phenotype and natural history VEOIBD are not well described. Methods We performed a retrospective cohort study patients diagnosed with (6 years age younger) between 2008 2013 at 25 North American centers. Eligible each center were randomly selected for chart review. abstracted data diagnosis 1, 3, 5 after diagnosis. compared clinical features outcomes younger than 3 children to 6...
As cure is attainable in very few cases of lung cancer, the imperative issue to make quality life (QOL) as good possible part palliative care package. The aim this paper was evaluate baseline QOL cancer patients and observe its association with various clinical parameters overall respiratory status. A total 101 were administered European Organization for Research Treatment Cancer core (EORTC QLQ-C30, version 3) questionnaire. Clinical profile measures status, including spirometry, dyspnoea,...
Pediatric patients with inflammatory bowel disease (IBD) have high rates of abdominal pain. The study aims were to (1) evaluate biological and psychological correlates pain in depressed youth IBD (2) determine predictors Crohn's (CD) ulcerative colitis (UC). Seven hundred sixty-five aged 9 17 years seen over 3 at 2 sites screened for depression. Depressed completed comprehensive assessments pain, (depression anxiety), (IBD-related, through activity indices laboratory values) realms. Two...
BackgroundManaging patients with inflammatory bowel disease requires multidisciplinary coordination. Technological advances have enhanced access to care for and improved physician interactions. The primary aim of our project was convene diverse institutions specialties through a multisite virtual conferencing platform discuss complex patient management.
Background/Aims: Neuropsychiatric symptoms (NPS) in dementia pose great challenges for residents and staff nursing homes. The Targeted Interdisciplinary Model Evaluation Treatment of Symptoms (TIME) has recently a randomized controlled trial demonstrated reductions NPS. We explored the participating staff's experiences with model how it meets when dealing complexity NPS.Methods: Three to six months after end intervention, we interviewed 32 caregivers, leaders, physicians trial, five focus...
Children with inflammatory bowel disease [IBD] are disproportionally affected by recurrent Clostridioides difficile infection [rCDI]. Although faecal microbiota transplantation [FMT] has been used good efficacy in adults IBD, little is known about outcomes associated FMT paediatric IBD.We performed a retrospective review of at 20 centres the USA from March 2012 to 2020. and without IBD were compared determined differences for rCDI. In addition, children successful outcome predictors success....
Systemic steroid exposure, while useful for the treatment of acute flares in inflammatory bowel disease (IBD), is associated with an array side effects that are particularly significant children. Technical advancements have enabled locoregional intraarterial delivery directly into specific segments gastrointestinal tract, thereby maximizing tissue concentration limiting systemic exposure. We investigated feasibility administration a cohort nine pediatric patients who had IBD. This approach...
Inflammatory bowel disease-associated liver diseases (IBD-LDs) include autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and an overlap syndrome. Prospective unbiased multicenter data regarding the frequency of IBD-LD in patients with pediatric inflammatory disease (IBD) are lacking. We examined early alanine aminotransferase (ALT) γ-glutamyl transpeptidase (GGT) elevations children diagnosed as having IBD assessed likelihood IBD-LD.Data collected from prospective...
Since anxiety in patients with dementia is a complex, understudied phenomenon, this paper presents clinicians' experiences of population. Semi-structured interviews were conducted seven clinicians experienced elderly (65 years and above), then evaluated via qualitative content analysis. Analysis revealed three main categories: A reaction to loss worries, symptoms depression interfere each other, dementia-a multidisciplinary task. Anxiety population perhaps best understood as existential...
The primary goal of rhinoplasty is patient satisfaction and improved quality life. present study was conducted to assess with face nose appearance, life after rhinoplasty.Patients presenting for completed the FACE-Q survey. This a new instrument that measures patient-reported outcomes in those undergoing aesthetic procedures. scales include facial appearance overall, nose, psychological well-being, psychosocial distress social function.Sixty-five patients at pre-operative post-operative...