A5101446594- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Suicide and Self-Harm Studies
- Radiation Dose and Imaging
- Ophthalmology and Visual Impairment Studies
- Healthcare Policy and Management
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Corneal surgery and disorders
- Emergency and Acute Care Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Obesity, Physical Activity, Diet
- Coronary Interventions and Diagnostics
- Patient-Provider Communication in Healthcare
- Organ Transplantation Techniques and Outcomes
- Radiology practices and education
- Healthcare professionals’ stress and burnout
- Lung Cancer Treatments and Mutations
- Patient Satisfaction in Healthcare
- Cancer survivorship and care
- Photoacoustic and Ultrasonic Imaging
- Pediatric Urology and Nephrology Studies
- Cancer Cells and Metastasis
- Posttraumatic Stress Disorder Research
China Pharmaceutical University
2025
Huazhong University of Science and Technology
2018-2024
Central Queensland University
2024
First Hospital of China Medical University
2014-2023
China Medical University
2014-2023
Shanghai Sixth People's Hospital
2023
Shanghai Jiao Tong University
2023
Texas Tech University
2007-2022
Texas Tech University Health Sciences Center
2006-2021
State Council of the People's Republic of China
2015-2019
Combining photothermal therapy (PTT) with clinical technology to kill cancer via overcoming the low tumor targeting and poor efficiency has great potential in basic researches. A brand‐new MoS 2 nanostructure is designed fabricated, i.e., layered hollow spheres (LMHSs) strong absorption near‐infrared region (NIR) high conversion a simple fast chemical aerosol flow method. Owing curving spherical structure, as‐prepared LMHSs exhibit unique electronic properties comparing nanosheets. In vitro...
There are acknowledged risks of metastasis cancer cells and obstructing treatment from hypoxia. In this work, we design a multifunctional nanocomposite for treating hypoxia based on the oxygen release capability CuO triggered by microwave (MW). Core-shell CuO@ZrO2 nanocomposites prepared confining nanoparticles within cavities mesoporous ZrO2 hollow nanospheres. 1-Butyl-3-methylimidazolium hexafluorophosphate (IL) is loaded to improving thermal therapy (MWTT). 1-Tetradecanol (PCM) introduced...
This study develops a simple hollow ZrO2 nanostructure as carrier to encapsulate ionic liquid (IL), which integrates the CT imaging function of shell and microwave susceptibility IL core. The can be used multifunctional theranostic agent via combining diagnostic therapeutic modalities into one "package". Based on properties, tumor inhibiting ratio over 90% in mice models after one-time thermal therapy upon irradiation. In vitro vivo results prove potential application for real-time...
Purpose: To develop and validate a radiomic signature to identify EGFR mutations in patients with advanced lung adenocarcinoma. Methods: This study involved 201 adenocarcinoma (140 the training cohort 61 validation cohort). A total of 396 features were extracted from manual segmentation based on enhanced non-enhance CT imaging after image preprocessing. The Lasso algorithm was used for feature selection, 6 machine learning methods construct radiomics models. Receiver operating characteristic...
To develop a cell-based in vitro thyroid-stimulating hormone (TSH) biological activity assay that can simulate vivo pharmacodynamic mechanisms, we constructed two HEK293-TSHR cell lines based on main signaling pathways (Gαs-cAMP-PKA and Gαq/11-PLC-Ca2+) TSH depends for its physiological function. These stably expressed the luciferase reporter driven by cAMP response element (CRE) nuclear factor of activated T cells (NFAT) element, reporter-gene assays (RGAs) were correspondingly established...
The combination of therapies and monitoring the treatment process has become a new concept in cancer therapy. Herein, gelatin-based microcapsules have been first reported to be used as microwave (MW) susceptible agent magnetic resonance (MR) imaging contrast for MW thermotherapy. Using simple coacervation methods, ionic liquid (IL) Fe3O4 nanoparticles (NPs) were wrapped microcapsules, these showed good heating efficacy vitro under irradiation. results cell tests indicated that...
Mitochondria play a key role in tumor therapy, not only chemotherapy and photothermal but also target microwave thermotherapy.
Demoralization is a form of psychological distress that may cause suicidal ideation. syndrome common among cancer patients, but there has been little empirical study on the association ideation with demoralization, depression, and anxiety in this population. This aims to investigate prevalence high demoralization patients mainland China contribution beyond impact self-report depression anxiety. In cross-sectional study, 303 were invited complete questionnaires. total, 14.5% participants...
Combined thermo-chemotherapy displays outstanding synergically therapeutic efficiency when compared with standalone thermotherapy and chemotherapy. Herein, we developed a smart tri-stimuli-responsive drug delivery system involving X@BB-ZrO2 NPs (X represents loaded IL, DOX, keratin tetradecanol) based on novel ball-in-ball-structured ZrO2 nanoparticles (BB-ZrO2 NPs). The microwave energy conversion of BB-ZrO2 was 41.2% higher than that traditional single-layer due to the cooperative action...
Abstract Background Although tobacco use in the United States has declined over past 20 years, cigarette among college students remains high. Additional research is thus needed to determine how university control policies and preventive education programs affect students' smoking behaviors. Methods Approximately 13,000 undergraduate at 12 universities or colleges state of Texas completed a web-based survey. College were obtained from survey administrators websites. Logistic regression...
The current study investigated the effects of immigration status, acculturation, and health beliefs on use preventive non-preventive visits, through a nationally representative sample U.S.-born foreign-born adults. adults were found to have significantly more visits than immigrants. predicting education, having usual source care, other public insurance stronger among immigrants U.S.-born. Health confidence believing in need for predicted numbers both but correlated little with either type...
Purpose The purpose of this cross-sectional survey was to investigate how family adaptability and cohesion, coping styles depression affect suicide ideation in patients with malignant tumors. This study also aimed examine the potential mechanisms cohesion suicidal ideation.Methods From January 2019 May 2019, 357 tumors who were admitted a Chinese general hospital surveyed. Patient Health Questionnaire-9 version Family Adaptability Cohesion Evaluation Scale II, Medical Coping Modes...
Objectives: The objectives of this study were to test whether there are ethnic differences in parents' perceptions the participatory styles their children's physicians, and determine how Hispanic ethnicity influences factors that correlated with styles. Study Design: We conducted a population-based cross-sectional telephone survey 111 counties West Texas. Parents children adolescents 3 18 years age (n = 3876) included analyses. Methods: decision-making (PDM) style physicians was measured by...
To determine the individual variability of dark-adapted pupil diameter over 2 testing sessions using a standardized dark-adaptation protocol.Texas Tech University Health Sciences Center, Lubbock, Texas, USA.In this prospective observational cohort study, 40 volunteers with no history ocular disease, surgery, or injury other than requirement for refractive correction were included. The right eye was tested. A protocol used that controlled accommodation and patient alertness. Infrared, still...
Purpose: To investigate the specific targeting property of lymphatic vessel endothelial hyaluronan receptor-1 binding polyethylene glycol-coated ultrasmall superparamagnetic iron oxide (LYVE-1-PEG-USPIO) nanoparticles to mouse cells (MLECs). Methods: A ligand target vessels was selected by immunohistochemical staining on sections a Lewis subcutaneous transplanted tumor. The z-average hydrodynamic diameter (HD), zeta potential, and relaxivity PEG-USPIO LYVE-1-PEG-USPIO were determined with...
Necrosis targeting and imaging has significant implications for evaluating tumor growth, therapeutic response, delivery of therapeutics to perinecrotic zones. Hypericin is a hydrophobic molecule with high necrosis affinity fluorescence properties. To date, the safe effective hypericin areas in vivo remains challenge because its incompatible biophysical address this issue, we have developed biodegradable nanoparticle (Hyp-NP) tumors imaging. The was using methoxy poly(ethylene...
Invasive fractional flow reserve (FFR) measured by a pressure wire is reference standard for evaluating functional stenosis in coronary artery disease. Coronary computed tomography angiography–derived (CT-FFR) uses advanced computational analysis methods to noninvasively obtain FFR results from single conventional angiography data evaluate the hemodynamic significance of More and more evidence has found good correlation between noninvasive CT-FFR invasive FFR. proven its potential optimizing...
Objectives. To identify factors related to elderly consumers' choice of pharmacy types and their overall satisfaction with services provided by: a single community pharmacy, multiple pharmacies primary mail order pharmacy. Data. Data were extracted from the Texas Tech 5000 survey consumers, age 65 years or older, in West Texas. The contains information about respondents' health use, service accessibility quality, insurance coverage, beliefs, status, demographics, as well other health-related...