A5050266059- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- GDF15 and Related Biomarkers
- Adenosine and Purinergic Signaling
- Biochemical and Molecular Research
- Genetics and Neurodevelopmental Disorders
- Ferroptosis and cancer prognosis
- Glutathione Transferases and Polymorphisms
- Bladder and Urothelial Cancer Treatments
Yuhuangding Hospital
2024
Qingdao University
2024
Sun Yat-sen University
2022-2023
Sixth Affiliated Hospital of Sun Yat-sen University
2022-2023
Abstract Metabolic reprogramming can contribute to colorectal cancer progression and therapy resistance. Identification of key regulators metabolism could provide new approaches improve treatment reduce recurrence. Here, we demonstrate a critical role for the COP9 signalosome subunit CSN6 in rewiring nucleotide cancer. Transcriptomic analysis patient samples revealed correlation between expression purine pyrimidine metabolism. A colitis-associated model established that Csn6 intestinal...
<div>Abstract<p>Metabolic reprogramming can contribute to colorectal cancer progression and therapy resistance. Identification of key regulators metabolism could provide new approaches improve treatment reduce recurrence. Here, we demonstrate a critical role for the COP9 signalosome subunit CSN6 in rewiring nucleotide cancer. Transcriptomic analysis patient samples revealed correlation between expression purine pyrimidine metabolism. A colitis-associated model established that...
<p>Table S3</p>
<p>Table S1</p>
<div>Abstract<p>Metabolic reprogramming can contribute to colorectal cancer progression and therapy resistance. Identification of key regulators metabolism could provide new approaches improve treatment reduce recurrence. Here, we demonstrate a critical role for the COP9 signalosome subunit CSN6 in rewiring nucleotide cancer. Transcriptomic analysis patient samples revealed correlation between expression purine pyrimidine metabolism. A colitis-associated model established that...
<p>Table S4</p>
<p>Supplementary Materials and Methods; Supplementary Figure S1-S11</p>
<p>Table S2</p>
<p>Table S3</p>
<p>Table S2</p>
<p>Table S1</p>
<p>Supplementary Materials and Methods; Supplementary Figure S1-S11</p>
<p>Table S4</p>