A5100682210- Photosynthetic Processes and Mechanisms
- Heat shock proteins research
- Plant Stress Responses and Tolerance
- Astrophysics and Cosmic Phenomena
- Plant Molecular Biology Research
- Gamma-ray bursts and supernovae
- Dark Matter and Cosmic Phenomena
- Geology and Paleoclimatology Research
- Particle Detector Development and Performance
- Archaeology and ancient environmental studies
- thermodynamics and calorimetric analyses
- Cancer-related molecular mechanisms research
- Mitochondrial Function and Pathology
- Insect and Pesticide Research
- Cancer, Hypoxia, and Metabolism
- Polysaccharides and Plant Cell Walls
- Noncommutative and Quantum Gravity Theories
- Pacific and Southeast Asian Studies
- Radio Astronomy Observations and Technology
- Plant Reproductive Biology
- Pleistocene-Era Hominins and Archaeology
- Pulsars and Gravitational Waves Research
- Fungal and yeast genetics research
- ATP Synthase and ATPases Research
- Radiation Detection and Scintillator Technologies
Hebei Normal University
2014-2025
Hebei Science and Technology Department
2025
Chinese Academy of Sciences
2024
University of Colorado Anschutz Medical Campus
2024
University of Colorado Denver
2024
Zhengzhou University
2024
Institute of Automation
2024
Shanghai Jiao Tong University
2024
Changsha University of Science and Technology
2023
Nanjing University
2013-2023
Some gamma-ray bursts (GRBs) have a tera-electron volt (TeV) afterglow, but the early onset of this has not been observed. We report observations with Large High Altitude Air Shower Observatory (LHAASO) bright GRB 221009A, which serendipitously occurred within instrument's field view. More than 64,000 photons >0.2 TeV were detected first 3000 seconds. The flux began several minutes after trigger and then rose to peak ~10 seconds later. This was followed by decay phase, became more rapid ~650...
Abstract We present the first catalog of very-high-energy and ultra-high-energy gamma-ray sources detected by Large High Altitude Air Shower Observatory. The was compiled using 508 days data collected Water Cherenkov Detector Array from 2021 March to 2022 September 933 recorded Kilometer Squared 2020 January September. This represents main result most sensitive large coverage survey sky above 1 TeV, covering decl. −20° 80°. In total, contains 90 with an extended size smaller than 2° a...
Summary An increased concentration of cytosolic calcium ions (Ca 2+ ) is an early response by plant cells to heat shock. However, the molecular mechanism underlying heat‐induced initial Ca in plants unclear. In this study, we identified and characterized a heat‐activated ‐permeable channel plasma membrane Arabidopsis thaliana root protoplasts using reverse genetic analysis whole‐cell patch‐clamp technique. The results indicated that A. cyclic nucleotide‐gated ion 6 (CNGC6) mediates influx...
The involvement of calcium and calcium-activated calmodulin (Ca(2+)-CaM) in heat shock (HS) signal transduction wheat (Triticum aestivum) was investigated. Using Fluo-3/acetoxymethyl esters laser scanning confocal microscopy, it found that the increase intracellular free ion concentration started within 1 min after a 37 degrees C HS. levels CaM mRNA protein increased during HS at presence Ca(2+). expression hsp26 hsp70 genes up-regulated by addition CaCl(2) down-regulated chelator EGTA,...
Intracellular calcium (Ca(2+)) increases rapidly after heat shock (HS) in the Ca(2+)/calmodulin (Ca(2+)/CaM) HS signal transduction pathway: a hypothesis proposed based on our previous findings. However, evidence for increase Ca(2+) was obtained only through physiological and pharmacological experiments; thus, direct molecular genetic is needed. The role of phosphoinositide-specific phospholipase C (PI-PLC) poorly understood plant response to HS. In this work, atplc9 mutant plants displayed...
We report the discovery of an extended very-high-energy (VHE) gamma-ray source around location middle-aged (207.8 kyr) pulsar PSR J0622+3749 with Large High Altitude Air Shower Observatory (LHAASO). The is detected a significance $8.2\sigma$ for $E>25$~TeV assuming Gaussian template. best-fit (R.A., Dec.)$=(95^{\circ}\!.47\pm0^{\circ}\!.11,\,37^{\circ}\!.92 \pm0^{\circ}\!.09)$, and extension $0^{\circ}\!.40\pm0^{\circ}\!.07$. energy spectrum can be described by power-law index ${-2.92 \pm...
ABSTRACT PP7 is the first protein Ser/Thr phosphatase to be found interact with calmodulin (CaM) in plants. The T‐DNA insertion AtPP7 knockout line and overexpression lines were employed study specific function of AtPP7. impaired thermotolerance Arabidopsis seedlings while resulted plants increased thermotolerance. Results from real‐time polymerase chain reaction (PCR) showed that expression AtHSP70 AtHSP101 genes was up‐regulated after heat shock (HS) at 37 °C for 1 h. Protein gel blot...
The heat stress response is an important adaptation, enabling plants to survive challenging environmental conditions. Our previous work demonstrated that Arabidopsis thaliana Phosphoinositide-Specific Phospholipase C Isoform 9 (AtPLC9) plays role in thermotolerance. During prolonged treatment, mutants of AtPLC3 showed decreased resistance. We observed no obvious phenotypic differences between plc3 and wild type (WT) seedlings under normal growth conditions, but after shock, the displayed a...
We report the discovery of a UHE gamma-ray source, LHAASO J2108+5157, by analyzing LHAASO-KM2A data 308.33 live days. Significant excess induced showers is observed in both energy bands 25-100 TeV and $\gt$100 with 9.5 sigma 8.5 sigma, respectively. This source not significantly favored as an extensive angular extension smaller than point-spread function KM2A. The measured spectrum from 20 to 200 can be approximately described power-law index -2.83$\pm$ 0.18stat. A harder demanded at lower...
Recently, the LHAASO Collaboration published detection of 12 ultrahigh-energy γ-ray sources above 100 TeV, with highest energy photon reaching 1.4 PeV. The first PeV γ rays from astrophysical may provide a very sensitive probe effect Lorentz invariance violation (LIV), which results in decay high-energy superluminal scenario and hence sharp cutoff spectrum. Two are studied this work. No signature existence LIV is found their spectra, lower limits on scale derived. Our show that first-order...
• AtDjB1 belongs to the J-protein family in Arabidopsis thaliana. Its biological functions plants are largely unknown. In this study, we examined roles of resisting heat and oxidative stresses A. thaliana using reverse genetic analysis. knockout (atj1-1) were more sensitive stress than wildtype plants, displayed decreased concentrations ascorbate (ASC), increased hydrogen peroxide (H2O2) products after shock. Application H2O2 accelerated cell death seedling viability atj1-1. Exogenous ASC...
Oxidative stress is a major cause of diabetic nephropathy. Upregulation the key antioxidative transcription factor, nuclear factor-erythroid 2-related factor 2 (Nrf2), was found to prevent development The present study designed explore therapeutic effect Nrf2 induced by proteasomal inhibitor MG132 at low dose (10 μg/kg) on Transgenic type 1 (OVE26) mice displayed renal dysfunction with albuminuria 3 mo age, which time treatment started. After 3-mo MG132, function, morphology, and biochemical...
Abstract Background Psychological co-morbidities in irritable bowel syndrome (IBS) have been widely recognized, whereas less is known regarding the role of gut microbial and host metabolic changes clinical psychological symptoms IBS. Results A total 70 diarrhoea-predominant IBS (IBS-D) patients 46 healthy controls were enrolled this study. Stool urine samples collected from both groups for 16S rRNA gene sequencing metabolomic analysis. The results showed that fecal microbiota IBS-D featured...
The kilometer square array (KM2A) of the large high altitude air shower observatory (LHAASO) aims at surveying northern γ-ray sky energies above 10 TeV with unprecedented sensitivity. observations have long been one most powerful tools for dark matter searches, as, e.g., high-energy γ rays could be produced by decays heavy particles. In this Letter, we present first analysis LHAASO-KM2A, using 340 days data from 1/2-KM2A and 230 3/4-KM2A. Several regions interest are used to search a signal...
DNA-binding activity of a maize heat shock transcription factor (HSF) was induced by whole cell extract at 44°C. Addition the calcium ion chelator EGTA reduced binding HSF to element (HSE) in vitro. Re-addition CaCl2 sample pretreated with restored ability bind DNA. also directly adding non-heat-shock temperature, but not MgCl2. During HS 44°C, calmodulin (CaM) antagonists chlorpromazine (CPZ) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) inhibited concentration-dependent...
Abstract A sub-array of the Large High Altitude Air Shower Observatory (LHAASO), KM2A is mainly designed to observe a large fraction northern sky hunt for γ-ray sources at energies above 10 TeV. Even though detector construction still underway, half array has been operating stably since end 2019. In this paper, we present data analysis pipeline and first observation Crab Nebula, standard candle in very high energy astronomy. We detect signals from Nebula both ranges 100 TeV with...
SUMMARY Clathrin‐mediated endocytosis (CME) plays a key role in the internalization of plasma membrane‐localized proteins, lipids and extracellular substances; however, regulatory mechanism CME plants is unclear. In this work, we demonstrated that molecular chaperon HSP70‐9 required for Arabidopsis thaliana . Knocking out gene led to auxin‐related phenotypes accumulation auxin efflux carrier PINs root cells, indicating involved PIN trafficking process. Immunolocalization studies showed was...
On 9 October 2022, the Large High Altitude Air Shower Observatory (LHAASO) reported observation of very early TeV afterglow brightest-of-all-time gamma-ray burst 221009A, recording highest photon statistics in band ever obtained from a burst. We use this unique to place stringent constraints on energy dependence speed light vacuum, manifestation Lorentz invariance violation (LIV) predicted by some quantum gravity (QG) theories. Our results show that 95% confidence level lower limits QG...
Abstract The 70 kDa heat shock proteins function as molecular chaperones and are involved in diverse cellular processes. However, the functions of plant mitochondrial HSP70s (mtHSC70s) remain unclear. Severe growth defects were observed Arabidopsis thaliana mtHSC70-1 knockout lines, mthsc70-1a mthsc70-1b. Conversely, introduction gene into background fully reversed phenotypes, indicating that is essential for growth. loss resulted abnormal mitochondria alterations to respiration because an...
We previously reported the involvement of nitric oxide (NO) and cyclic nucleotide-gated ion channel 6 (CNGC6) in responses plants to heat shock (HS) exposure. To elucidate their relationship with tolerance Arabidopsis thaliana, we examined effects HS on several groups seedlings: wild type, cngc6, cngc6 complementation overexpression lines. After exposure, level NO was lower seedlings than wild-type but significantly elevated transgenic lines depending CNGC6 expression level. The treatment...
Abstract The annexins are a multifamily of calcium‐regulated phospholipid‐binding proteins. To investigate the roles in fiber development, four genes encoding putative annexin proteins were isolated from cotton ( Gossypium hirsutum ) and designated AnnGh3 , AnnGh4 AnnGh5 AnnGh6 . Quantitative reverse transcription‐polymerase chain reaction (qRT‐PCR) results indicated that preferentially expressed fibers, while transcripts predominantly accumulated roots. During AnnGh3/4/5 mainly rapidly...
Arabidopsis calmodulin isoforms CaM2/3/5 and CaM7 negatively regulate Ca2+ conductivity during heat shock by binding to an atypical IQ motif in cyclic nucleotide-gated ion channel 6.