A5034904172- Luminescence and Fluorescent Materials
- Crustacean biology and ecology
- Aquaculture Nutrition and Growth
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Ammonia Synthesis and Nitrogen Reduction
- Advanced Photocatalysis Techniques
- Liquid Crystal Research Advancements
- Electrochemical sensors and biosensors
- Supramolecular Chemistry and Complexes
- Adenosine and Purinergic Signaling
- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- MicroRNA in disease regulation
- HVDC Systems and Fault Protection
- Atmospheric chemistry and aerosols
- Transition Metal Oxide Nanomaterials
- Photochromic and Fluorescence Chemistry
- Air Quality and Health Impacts
- Analytical Chemistry and Chromatography
- T-cell and Retrovirus Studies
- Advanced DC-DC Converters
- Synthesis and characterization of novel inorganic/organometallic compounds
Chalmers University of Technology
2024
Zhejiang University
2007-2024
Institute of Advanced Science Facilities, Shenzhen
2022-2024
Shaoxing University
2021-2024
Huazhong Agricultural University
2022-2024
Sir Run Run Shaw Hospital
2024
Shaoxing People's Hospital
2018-2024
Guangxi University
2022-2024
KU Leuven
2023
Guangdong University of Petrochemical Technology
2022-2023
Abstract Background GDSL esterases/lipases are a newly discovered subclass of lipolytic enzymes that very important and attractive research subjects because their multifunctional properties, such as broad substrate specificity regiospecificity. Compared with the current knowledge regarding these in bacteria, our understanding plant is limited, although gene family species include numerous members many fully sequenced genomes. Only two genes from large rice esterase/lipase were previously...
Curcumin is a natural compound that appears to be promising for clinical application, as it has been shown in vitro and vivo studies exert antitumor effects by modulating multiple signaling cellular pathways. In the present study, of curcumin its mechanism action were investigated cultured breast cancer cells. The MTT assay was used determine effect on cell proliferation, flow cytometry detect alterations cycle, western blot analysis expression molecules involved proliferation apoptosis....
The discovery of a series novel, potent, and highly selective inhibitors the DNA damage control kinase chk2 is disclosed. Here we report first SAR study around this kinase. High-throughput screening purified human led to identification novel 2-arylbenzimidazole Optimization was facilitated using homology models docking inhibitors, leading potent 2h (IC50 15 nM). Compound an ATP-competitive inhibitor that dose dependently protects CD4+ CD8+ T-cells from apoptosis due ionizing radiation. This...
Luteolin is a flavonoid, which has been extensively investigated due to its antitumor effects; however, the underlying mechanisms of action remain largely unknown. The present study aimed investigate role luteolin in breast cancer (BC), and explored how suppresses growth induces apoptosis BC cells. MTS assay was used determine anticancer activity luteolin. Colony formation Transwell assays were performed evaluate effects on cell invasion. Cell cycle progression analyzed by flow cytometry. In...
Here we describe a new and sensitive flow electrochemical detection system that employs novel flow-field shaped solid electrode (FFSSE). The was constructed with 3D-printed thin-layer cell (TLFC) flat screen-printed FFSSE USB connection. This interface facilitates continuous accumulation square-wave anodic stripping voltammetry (ASV). distribution in the working space of TLFC simulated using finite element method (FEM) shape configuration electrodes were optimized accordingly. We...
Abstract The tumor microenvironment induces immunosuppression via recruiting and expanding suppressive immune cells such as regulatory T (Treg) to promote cancer progression. In this study, we documented that tumor-infiltrating CD73+ γδTregs were the predominant Tregs in human breast exerted more potent immunosuppressive activity than CD4+ or CD8+ Tregs. We further demonstrated cancer-associated fibroblast (CAF)–derived IL6, rather TGFβ1, induced γδTreg differentiation from paired normal...
The tumor microenvironment is closely linked to the initiation, promotion, and progression of solid tumors. Among its constitutions, immunologic cells emerge as critical players, facilitating immune evasion progression. Apart from their indirect impact on anti-tumor immunity, immunocytes directly influence neoplastic cells, either bolstering or impeding advancement. However, current therapeutic modalities aimed at alleviating immunosuppression regulatory effector cell populations may not...
For interleaved boost-type converters, both functions of voltage regulation and current balance are important. In this paper, the decoupled current-balancing control (DCBC) with two parallel loops is proposed. At first, small-signal transfer voltage-regulation loop balancing to controller output derived. The results show that proposed nominally decoupled. That is, PI-type controllers can be designed independently included implement DCBC. Additionally, single-sensor sampling-current strategy...
Abstract Antibody–drug conjugates (ADCs) have demonstrated effectiveness in treating various cancers, particularly exhibiting specificity targeting human epidermal growth factor receptor 2 (HER2)‐positive breast cancer. Recent advancements phase 3 clinical trials broadened current understanding of ADCs, especially trastuzumab deruxtecan, other HER2‐expressing malignancies. This expansion knowledge has led to the US Food and Drug Administration's approval deruxtecan for HER2‐positive HER2‐low...
Ionic polymer-metal composites (IPMCs) exhibit a large dynamic bending deformation due to the redistribution of counter-ions inside polymer. It has not been possible get high resolution data cation migration. The images obtained so far have only validated versatile actuation model. model states that electrically induced movement contributes volumetric stress change in membrane. In this work, visualization migration using fluorescent microscopy is created. results demonstrated letter help...
We employed a simple and low-cost method to synthesize MOF–Fe 2 O 3 nanoparticles, which exhibited excellent performance for N reduction under ambient conditions.
Septic acute kidney injury (AKI) is commonly associated with renal dysfunction and high mortality in patients. Owing to the rapid violent occurrence of septic AKI inflammation, there are no effective therapies clinically treat it. Embelin, a natural product, has potential regulatory role immunocytes. However, mechanism embelin remains unknown. This study aimed elucidate macrophage regulation lipopolysaccharide (LPS)-induced AKI. Embelin was intraperitoneally administered mice after LPS...
Semen quality is an important indicator that can directly affect fertility. In mammals, miRNAs in seminal plasma extracellular vesicles (SPEVs) and sperms regulate semen quality. However, relevant regulatory mechanism duck remains largely unclear. this study, SPEVs were isolated characterized by transmission electron microscopy (TEM), western blot (WB), nanoparticle tracking analysis (NTA). To identify the molecules affecting quality, we analysed miRNA expression of male ducks high group...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModels of polysilane high polymers. 1. Singlet photophysics linear permethylhexadecasilane (Si16Me34)Ya Ping Sun, Yoshitaka Hamada, Li Ming Huang, Jim Maxka, Jiunn Shyong Hsiao, Robert West, and Josef MichlCite this: J. Am. Chem. Soc. 1992, 114, 16, 6301–6310Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July...