- Coronary Interventions and Diagnostics
- Uterine Myomas and Treatments
- Acute Myocardial Infarction Research
- Minimally Invasive Surgical Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Rabies epidemiology and control
- Antiplatelet Therapy and Cardiovascular Diseases
- Breast Cancer Treatment Studies
- Endometrial and Cervical Cancer Treatments
- Cardiac Imaging and Diagnostics
- Lysosomal Storage Disorders Research
- Clinical practice guidelines implementation
- Anatomy and Medical Technology
- Pleural and Pulmonary Diseases
- Streptococcal Infections and Treatments
- Genomic variations and chromosomal abnormalities
- Gothic Literature and Media Analysis
- Primary Care and Health Outcomes
- Vasculitis and related conditions
- Prenatal Screening and Diagnostics
- Gynecological conditions and treatments
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Surgical Simulation and Training
- Bacillus and Francisella bacterial research
- Neurological diseases and metabolism
Assistance Publique – Hôpitaux de Paris
2019-2025
Hôtel-Dieu de Paris
2021-2025
Ecologie & Evolution
2019-2024
Centre de Recherche en Mathématiques de la Décision
2019
In patients with ST-elevation myocardial infarction (STEMI) who have multivessel disease, percutaneous coronary intervention (PCI) for nonculprit lesions (complete revascularization) is superior to treatment of the culprit lesion alone. However, whether complete revascularization that guided by fractional flow reserve (FFR) an angiography-guided procedure unclear.
Background: In patients with ST-segment–elevation myocardial infarction and multivessel disease, percutaneous coronary intervention (PCI) for nonculprit lesions guided by fractional flow reserve (FFR) is superior to treatment of the culprit lesion alone. Whether deferring PCI safe in this specific context questionable. We aimed assess clinical outcomes at 1 year artery disease an FFR-guided strategy lesions, according whether or not ≥1 was performed. Methods: Outcomes were analyzed...
La maladie de Pompe est une affection génétique multisystémique rare et grave, représentant un fardeau clinique économique important. Elle a été l'une des premières maladies musculaires génétiques à bénéficier d'une thérapie innovante : la enzymatique substitutive (TES), introduit il y plus 15 ans. Cette analyse rétrospective bases données nationales santé françaises (SNDS) vise estimer le nombre patients atteints traités par TES avec l'alglucosidase alfa (Myozyme®), décrire leur parcours...
Background In patients with distal bifurcation left main stem lesions requiring intervention, the European Bifurcation Club Left Main Coronary Stent Study trial found a non-significant difference in major adverse cardiac events (MACEs, composite of all-cause death, non-fatal myocardial infarction and target lesion revascularisation) favouring stepwise provisional strategy, compared systematic dual stenting. Aims To estimate 1-year cost-effectiveness versus stenting strategies. Methods Costs...
In patients with ST-segment elevation myocardial infarction (STEMI) who have multivessel disease, the FLOWER-MI trial found no significant clinical benefit to fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) compared angiography-guided PCI.Our aim was estimate cost-effectiveness and cost-utility of FFR-guided PCI, secondary endpoint trial.Costs, major adverse cardiovascular events (composite all-cause death, non-fatal [MI], unplanned hospitalisation leading...
Background: Telemedicine is increasingly viewed as a tool to provide wide range of health services. This article presents policy lessons drawn from the evaluation telemedicine experiments conducted in Paris region. Methods: We used mixed method design study projects commissioned by Regional Health Agency between 2013 and 2017. combined data analysis projects, review protocols, interviews with stakeholders. Results: identified following reasons for disappointing outcomes: outcome measure was...
<title>Abstract</title> Background Hysterectomy for benign pathologies is one of the most common gynecological surgeries. In recent years, robotic surgery has become an alternative to traditional surgery, but at a higher cost. Objective Estimate cost robot-assisted hysterectomy purpose supporting public decision-making, as well additional per major postoperative complication (ClavienDindo score ≥ 3) avoided month after versus laparoscopic. Methods Single-center retrospective study including...
To evaluate the cost-effectiveness of five prenatal screening strategies for trisomies (13/18/21) and other unbalanced chromosomal abnormalities (UBCA), following introduction cell-free DNA (cfDNA) analysis.A model-based analysis was performed to estimate prevalence, safety, screening-program costs healthcare different strategies, using a virtual cohort 652 653 pregnant women in France. Data were derived from French Biomedicine Agency published articles. Uncertainty addressed one-way...
Abstract Purpose: The economic evaluation reports the incremental cost utility ratio and budget impact of APBI vs standard external beam WBI for treatment post-menopausal women with early stage breast cancer. Methods materials: We compared 488 in arm (1 fraction per day delivered 5 days week over 3 or 6/6.5 weeks) to 490 ABPI (ten fractions twice one week). took perspective healthcare system, a 3-year time horizon; outcomes were quality adjusted life years (QALYs). QALYs calculated from...
The annual incidence of rabies deaths has been estimated in Cambodia at nearly 5.8/100,000 person-years. cost post exposure prophylaxis (PEP) and travel is potentially a significant barrier for exposed patients their families, although safety nets are place to provide the no low-income families. A decision-tree model was built estimate changes costs from patients’ perspective survival outcomes Institut Pasteur du Cambodge (IPC) PEP regimen after switch Thai Red Cross (TRC) WHO category II or...
The annual incidence of rabies deaths has been estimated in Cambodia at nearly 5.8/100,000 person-years. cost post exposure prophylaxis (PEP) and travel is potentially a significant barrier for exposed patients their families, although safety nets are place to provide the no low-income families. A decision-tree model was built estimate changes costs from patients' perspective survival outcomes Institut Pasteur du Cambodge (IPC) PEP regimen after switch Thai Red Cross (TRC) WHO category II or...
Background: The annual incidence of rabies deaths has been estimated in Cambodia at nearly 5•8/100,000 person-years. cost post exposure prophylaxis (PEP) and travel is potentially a significant barrier for exposed patients their families, although safety nets are place to provide the no low-income families.Method: A decision-tree model compared costs from patients’ perspective disease outcomes Institut Pasteur du Cambodge (IPC) PEP regimen versus Thai Red Cross (TRC) WHO category II or III...