A5063146525- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Kawasaki Disease and Coronary Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Effects of Exercise
- Inflammatory mediators and NSAID effects
- Cardiac tumors and thrombi
- Coronary Artery Anomalies
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Heart rate and cardiovascular health
- Acute Ischemic Stroke Management
Ajou University
2016-2025
Weatherford College
2022-2024
Ajou University Hospital
2008-2022
Gangnam Severance Hospital
2022
Human Factors (Norway)
2022
University of California, San Diego
1980
Stent implantation for coronary ostial lesions is challenging. This study evaluated the feasibility, safety, and immediate procedural results of Osfit™, innovatively designed sirolimus drug-eluting stent delivery system treatment lesions. The Osfit™ has a 5 mm long extended balloon proximal to (bare without mounted stent). When inflated at 1.5 atm, only bare acts like stopper. We technical feasibility in 49 patients with lesion (defined as stenosis within 3 from origin vessel) who had...
Abstract The ratio between the absolute number of neutrophils and lymphocytes (NLR) has recently emerged as a potential new biomarker predicting worse clinical conditions ranging from infectious disease to cardiovascular disease. Prognostic significance NLR in patients with ST-elevation myocardial infarction (STEMI) is not established. This study aimed investigate prognostic impact STEMI. We analyzed data outcomes 30-day survivors STEMI who received successful coronary intervention 2006...
Heart failure (HF) is a chronic condition with an unpredictable trajectory, making effective communication between patients and healthcare providers crucial for optimizing outcomes. This study aims to investigate compare the needs regarding HF trajectory palliative care identify factors associated of HF. A cross-sectional design was employed, involving 100 35 providers. Data were collected using structured questionnaires assessing needs, health literacy, self-care behavior, social support....
Heart failure is a chronic disease requiring lifetime self-management at home by patients, who often require additional support. However, the long-term nature of this presents great challenges for both heart patients and their family caregivers. The role caregivers critical, but little known about relationship between burden, stress, depressive symptoms, quality life in patients. We aimed to explore caregiver with identify factors associated caregivers' life. sample included 120 participants...
Abstract Background In some patients with nonischemic idiopathic dilated cardiomyopathy ( DCM ), left ventricular LV ) dysfunction improves spontaneously but can recur. The factors predicting recurrence of in recovered are poorly defined. We investigated the clinical, echocardiographic, and laboratory variables affecting who from . Hypothesis is impacted by variables. Methods study comprised 85 consecutively enrolled (62 males, age 57 ± 16 years) achieved a restoration systolic function....
Background:The functional significance of an intermediate coronary lesion is crucial for determining the treatment strategy, but age-related changes in cardiovascular function could affect epicardial stenosis. The aim this study was therefore to investigate impact age on fractional flow reserve (FFR) measurements patients with artery disease (CAD).Methods and Results:Intracoronary pressure intravascular ultrasound (IVUS) were performed 178 left anterior descending arteries morphological...
Microvascular function is a useful predictor of left ventricular functional changes in patients with ST-segment elevation myocardial infarction (STEMI). We evaluated the usefulness hyperemic microvascular resistance index (hMVRI) for predicting long-term major adverse cardiovascular events (MACEs) STEMI assessed immediately after primary percutaneous coronary intervention (PCI).hMVRI were 145 first acute treated PCI using an intracoronary Doppler wire. hMVRI was defined as ratio mean aortic...
(1) Background: Currently, limited data are available regarding the relationship between epicardial fat and plaque composition. The aim of this study was to assess visceral surrounding heart lipid core burden in patients with coronary artery diseases; (2) Methods: Overall, 331 undergoing angiography combined near-infrared spectroscopy intravascular ultrasound imaging were evaluated for adipose tissue (EAT) thickness using transthoracic echocardiography. Patients divided into thick EAT thin...
Elevated visit-to-visit blood pressure variability (BPV), independent of mean BP, has been associated with cardiovascular events. However, its impact after ST-elevation myocardial infarction (STEMI) not established. This study aimed to investigate the prognostic BPV on patients STEMI. We analyzed data and clinical outcomes STEMI survivors who underwent successful primary coronary intervention from 2003 2009. BP was measured at discharge 1, 3, 6, 12, 24, 36 months, we calculated as...
Left ventricular hypertrophy (LVH) had been associated with increased adverse cardiovascular events in hypertensive patients. Prognostic significance of LVH patients ST-elevation myocardial infarction (STEMI) is not established. This study aimed to investigate prognostic impact on the STEMI.We analyzed data and clinical outcomes 30-day survivors STEMI who underwent successful coronary intervention from 2003 2009. Definition was LV mass index (LVMI) >115 g/m(2) male >95 female. Patients were...
The amount of epicardial adipose tissue (EAT) has been demonstrated to correlate with the severity coronary artery disease (CAD) and CAD activity. aim this study is assess impact EAT on long term clinical outcomes in patients ST elevation myocardial infarction (STEMI) after percutaneous intervention (PCI).We analyzed data 761 (614 males, 57 ± 12 year-old) STEMI who underwent successful primary PCI from 2003 2009. All were divided into two groups: thick group, ≥ 3.5 mm thin < mm. end points...
Abstract Objectives We evaluated the usefulness of a fractional flow reserve (FFR) gradient across stent (ΔFFR ) for long‐term clinical outcomes after percutaneous coronary intervention (PCI) with drug‐eluting (DES). Background The meaning trans‐stent pressure DES implantation has not been estimated adequately. Methods FFR pull‐back and intravascular ultrasound (IVUS) were performed successful PCI in 135 left anterior descending artery lesions. ΔFFR was defined as stent. stent/length value...
Background: Our aim was to assess the relationship of index microvascular resistance (IMR) in left anterior descending (LAD) artery involved STEMI patients. Methods: Data 316 patients who had undergone primary percutaneous coronary intervention (PCI) were collected from three cardiovascular centers 2005 2015. In total, 246 with LAD enrolled for IMR evaluation. Patients divided into two groups respective cut-off value 30. All-cause mortality, ventricular function, improvement systolic and...
Prognostic significance between progression of left ventricular hypertrophy (LVH) and clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) is uncertain. The objective this study was to investigate prognostic impact LV mass index (LVMI) STEMI. We analyzed the data STEMI who received successful coronary intervention. A total 200 had echocardiographic follow-up 12 36 months were finally enrolled. According change LVMI compared baseline LVMI, classified into group...
With the present therapeutic advances in era of primary percutaneous coronary intervention (PCI), role β-blockers ST elevation acute myocardial infarction (STEMI) has remained contentious.We analyzed data and clinical outcomes 901 STEMI patients who had undergone PCI. We classified into β-blocker (n = 598) non-β-blocker groups 303).The cumulative incidence all-cause death was 10.0% group 25.4% (p < 0.001). The major adverse cardiac events (MACE) 22.1% 34.3% relative hazard ratio (HR) for...
Technically refined angiograms and scintigrams were extremely sensitive in demonstrating experimental canine thromboemboli, both immediately after embolization during the entire course of embolic lysis. Technical refinements included subselective, scintigraphically guided, magnification arteriography eight-view perfusion scintigraphy. During thromboembolic lysis, excellent angiographic-scintigraphic correlation persisted. For every postembolic defect, basis could be demonstrated...
Microvascular damage due to distal embolization during percutaneous coronary intervention (PCI) is an important cause of periprocedural myocardial infarction. We assessed the lipid-core plaque using near-infrared spectroscopy (NIRS) and microvascular dysfunction invasively with index microcirculatory resistance (IMR) evaluated their relationship.This study pilot retrospective observational study. analyzed 39 patients who performed NIRS before after PCI, while fractional flow reserve,...
Antiphospholipid syndrome (APS), the most common acquired hypercoagulable condition, is diagnosed by persistent presence of antiphospholipid antibodies and episodes vascular thrombosis.It may be an important predisposing factor for stent thrombosis, resulting in poor outcomes.Also, anti-platelet therapy non-responsiveness associated with thrombosis.We report a case 39-year-old man who after undergoing successful percutaneous coronary intervention significant artery disease suffered repeated...
We aimed to compare long-term clinical outcomes between modified mini-crush (modi-MC) technique with classic crush (crush) for treatment of bifurcation lesions.The modi-MC showed excellent procedural success and favorable 9-month outcomes.From January 2005 November 2009, we enrolled patients de novo lesions treated (n = 112 in 111 patients) 69 67 patients). Primary endpoint was rate major adverse cardiac events (MACE), a composite all-cause death, myocardial infarction (MI), target lesion...
In intermediate coronary artery disease, discordance between anatomical and functional assessments persists the diagnostic accuracy of an evaluation is not satisfactory for determining significance. We aimed to evaluate impact microvascular resistance on "anatomical-functional discordance".In 97 lesions 83 patients, minimum lumen area (MLA), fractional flow reserve (FFR), Δ(Pd/Pa-FFR), hyperaemic index (hMVRI) were measured using intravascular ultrasound intracoronary dual pressure Doppler...