- Microbial Community Ecology and Physiology
- Marine Biology and Ecology Research
- Genomics and Phylogenetic Studies
- Marine Bivalve and Aquaculture Studies
- Coral and Marine Ecosystems Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- Environmental DNA in Biodiversity Studies
- Nematode management and characterization studies
- Parasite Biology and Host Interactions
- Protist diversity and phylogeny
- Bacterial biofilms and quorum sensing
- Crustacean biology and ecology
- Antimicrobial Resistance in Staphylococcus
- Pharmacological Effects and Toxicity Studies
- Nanoparticles: synthesis and applications
- Cystic Fibrosis Research Advances
- Marine Biology and Environmental Chemistry
- Rheumatoid Arthritis Research and Therapies
- Inflammatory Biomarkers in Disease Prognosis
- Synthesis and properties of polymers
- Graphene and Nanomaterials Applications
- Plant-Microbe Interactions and Immunity
- Aquatic Invertebrate Ecology and Behavior
- Adipokines, Inflammation, and Metabolic Diseases
- Microbial Metabolism and Applications
Jiujiang University
2021-2024
Children's Hospital of Los Angeles
2023-2024
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2020-2023
Hong Kong University of Science and Technology
2020-2023
University of Hong Kong
2020-2023
Guizhou University
2012-2022
Zhejiang Sci-Tech University
2022
Fujian Normal University
2022
Macau University of Science and Technology
2021
National Center for AIDS/STD Control and Prevention,China CDC
2013
Harmful algal blooms (HABs) in natural waters are of escalating global concern due to their detrimental impact on environmental health. Emerging evidence indicates that algae-bacteria symbionts can affect HAB features, though much about this interplay remains largely unexplored. The current study isolated a new species Mucilaginibacter (type strain JXJ CY 39 T ) from culture biomass the bloom-causing Microcystis aeruginosa FACHB-905 (Maf) Lake Dianchi, China. Strain was an aerobic,...
Abstract An alpha-proteobacterial strain JXJ CY 53 T was isolated from the cyanosphere of Microcystis sp. FACHB-905 (MF-905) collected Lake Dianchi, China. observed to be an aerobic, Gram-stain-negative, oval shaped, and mucus-secreting bacterium. It had C 18:1 ω7c 16:0 as major cellular fatty acids, Q-10 predominant ubiquinone, sphingoglycolipid, diphosphatidylglycerol, phosphatidylcholine, phosphatidylmethylethanolamine polar lipids. The G + content DNA 65.85%. bacterium 16S rRNA gene...
Marine biofilms are multispecies microbial communities on surfaces that crucial to the marine environment. They cause corrosion, biofouling, and transmission of pathogens thus pose a great threat public health maritime industry. To control biofilms, effective environmentally friendly antibiofilm compounds highly needed. Elasnin is potent compound exhibits high efficiency in inhibiting but its mode action remains unclear. In present study, multiomic analysis combined with quorum-sensing...
Abstract The scaly-foot snail (Chrysomallon squamiferum) inhabiting deep-sea hydrothermal vents in the Indian Ocean relies on its sulphur-oxidising gammaproteobacterial endosymbionts for nutrition and energy. In this study, we investigate specificity, transmission mode, stability of multiple populations dwelling five vent fields with considerably disparate geological, physical chemical environmental conditions. Results population genomics analyses reveal an incongruent phylogeny between...
Shinkaia crosnieri (Munidopsidae) is a squat lobster that dominates both deep-sea hydrothermal vent and methane seep communities in the Western Pacific. Previous studies comparing S. living two types of habitats have suffered from methodological and/or sample size limits. Here, using transcriptome-wide genetic markers 44 individuals, we reveal extent connectivity between population collected South China Sea (SCS) another Okinawa Trough (OT), as well their signatures local adaptation....
Biofilm is made up of microbes and their extracellular matrix, making microorganisms highly tolerant, resistant, resilient to a wide range antimicrobials. treatment with conventional antimicrobial agents can accelerate the evolution spread resistance due reduced efficacy increased gene transfer differentiation within biofilms. Therefore, effective biofilm-targeting compounds are currently sought after. In present study, we identified elasnin as potent compound against methicillin-resistant...
In eutrophic water, attached bacteria of Microcystis play an important role in the formation, development, and degradation blooms. A novel actinobacterium, designated as JXJ CY 35 T , was isolated from culture mass aeruginosa FACHB-905 (Maf) collected Lake Dianchi, Yunnan Province, China. Strain gram-positive, acid-fast staining, aerobic, with short rod-shaped cells, positive for catalase, negative oxidase. The isolate able to grow at 10.0–36.0°C, pH 4.0–10.0, tolerate up 5.0% (w/v) NaCl,...
Many deep-sea invertebrates largely depend on chemoautotrophic symbionts for energy and nutrition, some of them have reduced functional digestive tracts. By contrast, mussels a complete system although in their gills play vital roles nutrient supply. This remains can utilise available resources, but the associations among gut microbiomes these remain unknown. Specifically, how microbiome reacts to environmental change is unclear.The meta-pathway analysis showed nutritional metabolic mussel...
The intra-host composition of horizontally transmitted microbial symbionts can vary across host populations due to interactive effects genetics, environmental, and geographic factors. While adaptation local habitat conditions drive subdivision symbiont strains, it is unknown how differences in ecological characteristics among host-symbiont associations influence the genomic structure populations. To address this question, we sequenced metagenomes different deep-sea mussel Bathymodiolus...
Double-stranded RNA-binding proteins are small molecules in the RNA interference (RNAi) pathway that form RNAi machinery together with Dicer-like protein (DCL) as a cofactor. This cuts double-stranded (dsRNA) to multiple interfering RNAs (siRNAs). Our goal was clarify function of DRB tomato resistant TYLCV. In this experiment, expression SlDRB1 and SlDRB4 genes analyzed leaves by qPCR, resistance TYLCV investigated virus-induced gene silencing (VIGS). Then, peroxidase activity determined....
Abstract Information on genetic divergence and migration patterns of vent‐ seep‐endemic macrobenthos can help delimit biogeographical provinces provide scientific guidelines for deep‐sea conservation under the growing threats anthropogenic disturbances. Nevertheless, related studies are still scarce, impeding informed these hotspots biodiversity. To bridge this knowledge gap, we conducted a population connectivity study galatheoid squat lobster Shinkaia crosnieri – foundation species widely...
Abstract Background Urine organic acid (UOA) analysis is essential for the diagnosis of inborn errors metabolism (IEMs). Traditionally, UOA performed with gas chromatography-mass spectrometry (GC-MS) and requires time-consuming sample preparation steps including liquid-liquid extraction derivatization. The rapid development Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS/MS) in past few years provides opportunity to perform a dilute-and-shoot methodology. We...
Abstract Background N-terminal-proBNP (NT-proBNP), a short peptide originating from the cleavage of proBNP by Corin, can be used as diagnostic test in individuals presenting with signs and symptoms consistent heart failure (HF). QuidelOrtho Diagnostics released its latest reformulation NT-proBNP assay, Vitros II assay. The analytical performance this assay was evaluated. Methods Repeatability, reproducibility, carryover were assessed using quality control material. measuring range clinical...
Abstract The intra-host composition of horizontally transmitted microbial symbionts can vary across host populations due to interactive effects genetics, environmental and geographic factors. While adaptation local habitat conditions drive subdivision symbiont strains, it is unknown whether these patterns are universal how differences in ecological characteristics among host-symbiont associations influence the genomic structure populations. To address this question, we sequenced metagenomes...
Abstract A novel alphaproteobacterial strain JXJ CY 41 T was isolated from a culture mass of Microcystis , collected Lake Dianchi, south-west, China. Strain gram-negative, aerobic, motile, with rod-shaped cells (0.4–1.0 × 1.7–3.5 μm). It positive for catalase and starch hydrolysis, negative oxidase hydrolysis Tweens (20, 40, 80). Growth occurred at 10–44°C, pH 5.0–10.0, 0–5.0% ( w / v ) NaCl. Major fatty acids included C 16:0 (28.1%), 11-methyl 18:1 ω7c (36.7%) (20.8%). Q10 the sole...
Abstract Background Tacrolimus and cyclosporine are common immunosuppressive drugs used in the prevention treatment of solid-organ transplant rejection (e.g., kidney, liver, heart). Other indications include several autoimmune diseases such as Crohn’s disease, hepatitis, rheumatoid arthritis. To prevent toxicity while achieving therapeutic efficacy, tacrolimus whole blood specimens commonly measured medical centers so that their dosages can be precisely adjusted. Different from adult...