A5032615753- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- COVID-19 epidemiological studies
- Bone Tissue Engineering Materials
- Immune responses and vaccinations
- Viral gastroenteritis research and epidemiology
- Syphilis Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- COVID-19 and Mental Health
- Bacillus and Francisella bacterial research
- Sports Performance and Training
- Olfactory and Sensory Function Studies
- CRISPR and Genetic Engineering
- Marine Biology and Environmental Chemistry
- interferon and immune responses
- Polymer Surface Interaction Studies
- Adhesion, Friction, and Surface Interactions
- Paleontology and Stratigraphy of Fossils
- Genetics and Physical Performance
- COVID-19 Impact on Reproduction
- Calcium Carbonate Crystallization and Inhibition
Universidade Federal de Minas Gerais
2020-2025
Universidade Federal da Bahia
2024-2025
Fundação Hospitalar do Estado de Minas Gerais
2024
Hospital Ana Nery
2024
Instituto Federal de Educação, Ciência e Tecnologia de Minas Gerais
2021
Instituto de Ciencias Tecnológicas
2021
Hermes Arzneimittel (Germany)
2021
Universidade Federal do Rio de Janeiro
2021
Abstract ACE2 and TMPRSS2 are key players on SARS-CoV-2 entry into host cells. However, it is still unclear whether expression levels of these factors could reflect disease severity. Here, a case–control study was conducted with 213 positive individuals where cases were defined as COVID-19 patients respiratory distress requiring oxygen support (N = 38) controls those mild to moderate symptoms the who did not need therapy along entire clinical course 175). mRNA evaluated in nasopharyngeal...
Background The angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease (TMPRSS2) are central human molecules in SARS-CoV-2 virus-host interaction. Evidence indicates that ACE1 may influence ACE2 expression. This study aims to determine whether ACE1, ACE2, TMPRSS2 mRNA expression levels, along with Alu 287 bp polymorphism ( rs4646994 ), contribute severity mortality of COVID-19. Methods Swabs were collected two Brazilian cities 2020: Belo Horizonte n = 134) Rio de Janeiro...
Applying the theories of Materials Science and Engineering to describe composition hierarchy microstructures that comprise biological systems could help search for new materials results in a deeper insight into evolutionary processes. The layered microstructure makes up freshwater bivalve Limnoperna fortunei shell, an invasive specie Brazil, was investigated utilizing SEM AFM determination morphology organization layers; XRD used determine crystalline phases calcium carbonate (CaCO3) present...
The rapid spread and increase of chikungunya (CHIKV) dengue (DENV) cases in Brazilian regions 2023 has raised concerns about the impact arboviruses on public health. Epidemiological genomic surveillance was performed to estimate introduction CHIKV DENV Brazil. This study obtained results from Hermes Pardini (HP), a private medical laboratory, Health Department Minas Gerais state (SES-MG). We investigated positivity rates by analyzing 139,457 samples tested for (44,029 2022 95,428 2023)...
In early 2020, one of the most prevalent symptoms SARS-CoV-2 infection was loss smell (anosmia), found in 60-70% all cases. Anosmia used to occur early, concomitantly with other symptoms, and often persisted after recovery for an extended period, sometimes months. addition disturbance, COVID-19 has also been associated taste (ageusia). The latest research suggests that could spread from respiratory system brain through receptors sustentacular cells localized olfactory epithelium. virus...
The COVID-19 pandemic has created an unprecedented need for epidemiological monitoring using diverse strategies. We conducted a project combining prevalence, seroprevalence, and genomic surveillance approaches to describe the initial stages in Betim City, Brazil. collected 3239 subjects population-based age-, sex- neighborhood-stratified, household, prospective; cross-sectional study divided into three surveys 21 days apart sampling same geographical area. In first survey, overall prevalence...
Since its first identification in Brazil, the variant of concern (VOC) Gamma has been associated with increased infection and transmission rates, hospitalizations, deaths. Minas Gerais (MG), second-largest populated Brazilian state more than 20 million inhabitants, observed a peak cases deaths March–April 2021. We conducted surveillance study 1240 COVID-19-positive samples from 305 municipalities distributed across MG’s 28 Regional Health Units (RHU) between 1 March to 27 April The most...
This study investigated the association between IFITM3 rs12252 polymorphism and severity mortality of COVID-19 in hospitalized Brazilian patients. A total 102 patients were included, outcomes interest defined as death need for mechanical ventilation. Genotypes assessed using Taqman probes. No significant associations found original sample, both meta-analysis, incorporating previous studies that used a indicator, revealed no allelic C-recessive models. However, due to rarity T allele its...
Brazil is one of the countries most affected by COVID-19, with highest number deaths recorded. Brazilian Health Institutions have reported four main peaks positive COVID-19 cases. The last two waves were characterized emergence VOC Omicron and its sublineages. This study aimed to conduct a retrospective surveillance illustrating emergence, dissemination, diversification in 15 regional health units (RHUs) MG, second populous state Brazil, combining epidemiological genomic data. A total 5643...
The Relative Age Effect (RAE) suggests older athletes within an annual cohort have advantages over their younger peers. We hypothesized that could overcome these disadvantages through favorable α-actinin-3 (
Brazil was one of the most affected countries during SARS-CoV-2 pandemic, with more than 10 million cases and 300.000 deaths reported. Together increasing rate cases, emergence new variants concern (VOCs) possessing mutations that affect immunogenicity transmissibility poses a concerning burden in healthcare system. In Brazil, three such lineages are currently circulating: P.1, lineage firstly described Manaus, P.2, Rio de Janeiro, both already reported other cities country, B.1.1.7,...
Syphilis is a chronic disease caused by bacterial infection with Treponema pallidum as its etiological agent.This can manifest in various organs such the liver, skin and heart.In Brazil, syphilis public health issue mainly among pregnant women highest rate of notifications concentrated northeast, southeast south country.Given relevance field need to know reality each location for better development control measures, present study carried out analyses on epidemiological profile occurrence...
Abstract The Covid-19 pandemic has created an unprecedented need for epidemiological monitoring using diverse strategies. We conducted a project combining prevalence, seroprevalence, and genomic surveillance approaches to describe the initial stages in Betim City, Brazil. collected 3239 subjects population-based age-, sex- neighbourhood-stratified, household, prospective; cross-sectional study divided into three surveys 21 days apart sampling same geographical area. In first survey, overall...