A5083810571- COVID-19 Clinical Research Studies
- Contact Dermatitis and Allergies
- SARS-CoV-2 and COVID-19 Research
- Occupational exposure and asthma
- Hepatitis C virus research
- Pesticide Exposure and Toxicity
- SARS-CoV-2 detection and testing
- Animal Virus Infections Studies
- Drug-Induced Hepatotoxicity and Protection
- Liver Disease Diagnosis and Treatment
- Maternal and fetal healthcare
- Drug-Induced Adverse Reactions
- HIV/AIDS drug development and treatment
- Maternal and Perinatal Health Interventions
- HIV/AIDS Research and Interventions
- Hedgehog Signaling Pathway Studies
- COVID-19 and Mental Health
- Thermal Regulation in Medicine
- Botulinum Toxin and Related Neurological Disorders
- HIV Research and Treatment
- Genetic and rare skin diseases.
- Lymphoma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Medicine and Dermatology Studies History
- Erythropoietin and Anemia Treatment
Primary HealthCare
2024
Primary Health Care
2024
Hospitais da Universidade de Coimbra
2016-2022
Hospital Garcia de Orta
2015-2017
Hospital de Egas Moniz
2014
Hospital de São João
1999-2010
Summary Background Occupational allergic contact dermatitis (ACD) in healthcare workers (HCWs) is common, but systemic antibiotics are rarely reported as the cause. Objectives Characterize occupational ACD by handling antibiotics. Method A retrospective analysis was performed of caused among HCWs patch tested between 2010 and 2016 with a series Results We studied 4 female nurses aged 28–47 years who developed while working surgical departments. They had eczema hands, forearms or face, 1...
Introduction: The best route of delivery for the term breech fetus is still controversial. We aim to compare maternal and neonatal outcomes between vaginal cesarean deliveries.Material Methods: Multicentric retrospective cohort study singleton fetuses delivered vaginally or by elective section from January 2012 - October 2014. Primary were morbidity mortality.Results: Sixty five compared 1262 cesarean. Nulliparous women more common in group (69.3% vs 24.6%; p < 0.0001). Gestational age at...
Introduction First antiretroviral therapy (ART) is often switched to simpler, more potent or better tolerated regimens [ 1 , 2 ]. Although discontinuation rates are frequently studied, the durability of rarely approached. Materials and Methods Retrospective study with following objectives: analyze first ART schemes their in naive patients chronic HIV‐1 infections, evaluate factors influencing change, second‐line consequent virologic immunologic responses. Patients had follow‐ups a Central...
This study aimed to assess kinetics and predictive variables of humoral immune response mRNA SARS-CoV-2 vaccine administration.We collected blood samples before (T0) 15, 90, 180 days after vaccination (T1, T2, T3, respectively). The Quant Immunoglobulin (IgG) II Chemiluminescent Microparticle Immunoassay was used determine anti-spike IgG.In almost 3000 healthcare-collected at the three time points, we found following: 15 postvaccination, 97.6% subjects presented a robust IgG (>4160 AU/ml);...
Introdução: A dermatite de contacto alérgica, tal como a irritativa e as reações imediatas, urticária contacto, são principais doenças dermatológicas profissionais mas raramente notificadas aos sistemas nacionais vigilância riscos profissionais. Pretendemos avaliar profissões mais frequentemente relacionadas com o diagnóstico os alergénios envolvidos sua relação modificação da exposição profissional.Material Métodos: Efetuámos um estudo retrospetivo (2012 - 2014) nos pacientes que realizaram...
Acute hemorrhagic edema (AHE) is an uncommon self-limited disorder affecting young children triggered by infection, drugs, or immunization. A 2-year-old boy was observed due to sudden onset of painful and edematous purpuric papular plaque lesions the face upper extremities that started 2 weeks after H1N1 The patient also developed exuberant on dorsum hands. Complete blood count, biochemistry, urinalysis results were normal. Histopathological examination revealed perivascular periadnexial...
Health care workers (HCWs) have a high risk of infection with coronavirus disease 2019 (COVID-19), especially those treating patients confirmed or suspected diagnosis (front-line).To evaluate the incidence and prevalence COVID-19 among HCWs to analyse factors clinical characteristics infected ones.Observational, retrospective, single-center study (Centro Hospitalar e Universitário de Coimbra, Portugal). Data were collected from March 1 June 30, 2020.Overall, 211 (2.63%) out 8037 diagnosed...
Hepatitis C constitutes a major public health burden. In Portugal, the prevalence is estimated at 1-1.5% (1). Of these, only 30% are presumed to be diagnosed, which reveals that most infections go unknown. The objective of this study identify age-range distribution HCV diagnosis and high-prevalence birth groups could targeted for screening, as strategy increase patients who would benefit from treatment.Retrospective observational cohort chronic HCV-infected HIV co-infected followed an...
Cirrhosis secondary to HCV infection is expected peak in the next decade, particularly HIV co-infected subgroup and has become a leading cause of morbidity among these individuals. Efforts must be done estimate risk liver decompensation (LD) short term, order define appropriate time for treatment.Retrospective observational cohort study aimed assess LD group HIV/HCV patients diagnosed past 23 years central hospital Lisbon.(1) advanced fibrosis ≥F3; (2) treatment naïve or without sustained...
Long COVID is a recent pathological entity. Its manifestations and impact on health quality of life and, larger scale, at an economic social level may be very significant, reflecting challenge for the future. The family doctor plays major role in care these patients must aware this new reality. With study, we aim to determine prevalence long adult population registered Portuguese Primary Healthcare Unit, called USF Amatus, identify most frequent symptoms, its duration, individuals.
The decision to start hepatitis C virus (HCV) treatment and its timing remains controversial. As new regimens are approved, it is essential identify patients eligible for each regimen in a timed tailored approach. This study aims the reasons defer of chronic infection both HCV HCV/HIV infected patients.Retrospective observational cohort chronically with or without HIV infection, followed an infectious disease clinic Lisbon. Demographic, epidemiological, clinical, immunologic virologic data...
Introduction: Chromium has been responsible for occupational skin disease, both irritant and/or allergic contact dermatitis. In order to minimize this problem, regulatory measures limiting its use have implemented. The impact of these regulations should be monitored over time.
 Material and Methods: A retrospective study from 2009 2018 was carried out in the Department Dermatology assess temporal trend chromium sensitization evaluated by patch testing with potassium dichromate 0.5% pet,...
Introdução: A dermatite de contacto alérgica (DCA) constitui patologia profissional particularmente frequente em profissionais saúde. Os alergénios responsáveis podem variar ao longe do tempo, com a exposição ocupacional e o tipo trabalho.Objectivos Métodos: Com objetivo avaliar realidade local, foi feita uma análise retrospetiva dos saúde que realizaram testes epicutâneos no Serviço Dermatologia Centro Hospitalar Universitário Coimbra (CHUC), num período 6 anos (2010-2015), por suspeita...
INTRODUCTIONOccupational allergic contact dermatitis (ACD) is frequent among health care workers (HCW) and culprit allergens may vary with time, occupational setting exposure hazards. OBJECTIVES AND METHODSIn order to characterize the main in HCW its relevance, we performed a retrospective analysis of clinical data patch test (PT) results from who were studied Department Dermatology Coimbra Hospital University Centre (CHUC) between 2010-2015. All patients tested Baseline additional series,...
OBJECTIVE: To compare the rate of vaginal birth in women attempting after caesarean delivery (VBAC) through labour induction with dinoprostone versus a trial spontaneous labour. METHODS: A 10-year retrospective cohort study tertiary care hospital one prior delivery. Women who attempted VBAC were compared undergoing Logistic regression analyses performed to assess relationship between success and taking into account confounding variables. Both maternal neonatal safety studied find difference...
Introduction The SARS-CoV-2 pandemic has brought new and challenging problems to health care systems. More than ever, the screening identification of disease transmission chains proved be extremely complex important. accurate diagnosis remains as a fundamental pillar screening, which is currently based on molecular detection in respiratory samples. This strategy may insufficient for an effective control since diagnostic performance varies over time after exposure dependent sensitivity...
Background: The SARS-CoV-2 pandemic was responsible for the death of millions people around world, which accelerated study vaccines. BTN161b2 mRNA COVID-19 is a messenger RNA vaccine that encodes spike protein virus. However, duration protection conferred by this and factors associated with immune responses require validation in large cohorts.Methods: Here, we present data humoral response to vaccination 4264 healthcare workers, tested before (T0) 15 90 days (T1 T2, respectively) following...