A5045004585- Hydrocarbon exploration and reservoir analysis
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Hydraulic Fracturing and Reservoir Analysis
- RNA modifications and cancer
- Geological and Geophysical Studies
- Nuclear Engineering Thermal-Hydraulics
- Concrete Corrosion and Durability
- Thyroid Cancer Diagnosis and Treatment
- Nuclear reactor physics and engineering
- Radar Systems and Signal Processing
- Biomarkers in Disease Mechanisms
- Heat transfer and supercritical fluids
- Autophagy in Disease and Therapy
- Ion Transport and Channel Regulation
- Interprofessional Education and Collaboration
- Cancer Cells and Metastasis
- Dementia and Cognitive Impairment Research
- Nosocomial Infections in ICU
- Childhood Cancer Survivors' Quality of Life
- Ion channel regulation and function
- Lipid metabolism and biosynthesis
- Extracellular vesicles in disease
Wuhan University
2023-2025
Zhejiang Chinese Medical University
2025
Nankai University
2018-2024
State Key Laboratory of Medicinal Chemical Biology
2018-2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024
Wenzhou Medical University
2024
Wuhan Donghu University
2024
Harbin Engineering University
2022
China National Offshore Oil Corporation (China)
2019-2021
Taizhou Municipal Hospital
2021
Abstract Ferroptosis is a regulated iron-dependent cell death characterized by the accumulation of lipid peroxidation. A myriad facets linking amino acid, lipid, redox, and iron metabolisms were found to drive or suppress execution ferroptosis. However, how cells decipher diverse pro-ferroptotic stress activate ferroptosis remains elusive. Here, we report that protein O -GlcNAcylation, primary nutrient sensor glucose flux, orchestrates both ferritinophagy mitophagy for Following treatment...
This study aimed to investigate the working experiences and perceptions of hospital-based, pediatric medical social workers in China. Eight were interviewed. There three primary themes extracted through analysis: (1) negative experience perceived work challenges workers; (2) positive sense professional benefit for (3) development needs profession. While Chinese have encountered several difficulties challenges, they also benefited from work. Furthermore, provided constructive recommendations...
Sepsis-induced acute respiratory distress syndrome (ARDS) causes significant fatalities worldwide and lacks pharmacological intervention. Alveolar fluid clearance (AFC) plays a pivotal role in the remission of ARDS is markedly impaired pathogenesis ARDS. Here, we demonstrated that erythropoietin could effectively ameliorate lung injury manifestations lethality, restore function promote AFC rat model lipopolysaccharide (LPS)-induced Moreover, it was proven EPO-induced restoration occurs...
The purpose of this study was to explore whether prenatal gut microbiota (GM) and its functions predict the development offspring temperament. A total 53 mothers with a 1-year-old child 41 2-year-old were included in using mother-infant cohort from central China. Maternal fecal samples collected during third trimester analyzed 16S rRNA V3-V4 gene sequences. Temperament measured by self-reported data according primary caregiver. effects GM on offspring's temperament evaluated multiple linear...
Abstract To investigate the pressure wave propagation process caused by water hammer in reactor coolant system, a simulation model of three-loop main consisting core, steam generator, pump, and pressurizer, has been established. The core generator are simplified with equivalent pipes, pressurizer is established using two-phase canister, friction torque pump’s anti-reversal device developed. Unlike existing studies, this paper employs tracking method (WTM) for simulation. Finally, accuracy...
To explore the experiences and perceptions of oncology nurses providing hospice care in Chinese mainland. A descriptive phenomenological research method was utilized to describe experience among nurses. Eighteen were selected for interviews using purposive sampling from four grade tertiary hospitals Wuhan, Hubei province, China. The face-to-face semi-structured used collect data. Data recorded NVivo 12.0 analyzed Colaizzi's 7-step data analysis method. interview generated five major themes:...
Abstract Mitochondrial respiratory complex II utilizes succinate, key substrate of the Krebs cycle, for oxidative phosphorylation, which is essential glucose metabolism. Mutations cause cancers and mitochondrial diseases, raising a critical question (patho-)physiological functions. To address fundamental role in systemic energy metabolism, we specifically knockout SDHB mice liver, subunit that tethers catalytic SDHA transfers electrons to ubiquinone, found SHDB deficiency abolishes assembly...
The cable-beam anchorage zone is the vital load-bearing component in suspension bridge. For maintenance of such structure, a method probabilistic optimization was proposed by combining linear elastic fracture mechanics, structural reliability and life cycle cost analysis. In this method, optimal time obtained determining relative proportion between costs under condition that higher than minimum allowable reliability. While, total interval. Then, an example presented to verify with following...
In this paper, we consider the problem of adaptive multichannel signal detection in presence mismatch, and introduce a novel tunable detector, which is parameterized by two parameters. It has Constant false alarm rate (CFAR) property covers Kelly's generalized likelihood ratio test (KGLRT), Adaptive matched filter (AMF), coherence estimator (ACE) as its three special cases. The detector controls mismatched adjusting Remarkably, it can achieve improved performance for signals, enhanced...
Electromagnetic structures of novel modular arc-linear flux switching permanent magnet motor (NMAL-FSPM), that consists end (UPAL-FSPM) and doesn't consist (UAL-FSPM) are proposed comparatively researched in this paper by the finite element method (FEM). They used for scanning system to directly drive objects rotate back force within a limited angle instead reduction gearboxes kinematic mechanisms. these three kinds established. Magnetic field stator part, balance electromotive (back EMF)...
Fluid production of L field, Bohai Bay Basin, offshore eastern China is mainly from the Palaeogene Dongying D interval. The stratigraphy framework and depositional model braided-river delta system within interval are investigated using seismic, well log, core data response. interpreted as having been deposited in a lowstand tract. And two progradational successions recognized, including ascending order D2 D1. younger sandstone D1 greater thickness larger distribution area than elder Six...
The safety risk events that may occur during the cast-in-situ process of a concrete box girder an interchange bridge with high piers in mountainous areas are briefly listed. Based on background project Yunnan province, China, relative importance weights selected calculated by analytic hierarchy process, and uncertainty fuzziness solved using cloud theory to improve accuracy process; then improved likelihood–exposure–criticality method is used evaluate level events. It verified use...