A5088880132- RNA modifications and cancer
- Immune cells in cancer
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Retinoids in leukemia and cellular processes
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Adenosine and Purinergic Signaling
- Gestational Diabetes Research and Management
- Immune Response and Inflammation
- Extracellular vesicles in disease
- Cardiovascular Issues in Pregnancy
- Cancer-related molecular mechanisms research
- Angiogenesis and VEGF in Cancer
- Terahertz technology and applications
- Apelin-related biomedical research
- Cancer Immunotherapy and Biomarkers
- Cancer-related Molecular Pathways
- Catalytic C–H Functionalization Methods
- Cardiovascular Disease and Adiposity
- Nuclear Structure and Function
- Epigenetics and DNA Methylation
- Genetics and Neurodevelopmental Disorders
- Prostate Cancer Treatment and Research
- Phagocytosis and Immune Regulation
Nanjing Medical University
2025
Changzhou No.2 People's Hospital
2025
Second Xiangya Hospital of Central South University
2016-2024
Central South University
2011-2024
Zhengzhou University
2016-2024
Xiangya Hospital Central South University
2010-2024
Huazhong University of Science and Technology
2005-2024
Chengdu Medical College
2024
Songshan Lake Materials Laboratory
2024
Guangdong Medical College
2024
High-performance flexible pressure sensors have attracted a great deal of attention, owing to its potential applications such as human activity monitoring, man-machine interaction, and robotics. However, most high-performance are complex costly manufacture. These cannot be repaired after external mechanical damage lack tactile feedback applications. Herein, sensor based on MXene/polyurethane (PU)/interdigital electrodes is fabricated by using low-cost universal spray method. The sprayed...
Inflammation widely exists in many diseases and poses a great threat to human animal health. Rutin, quercetin-3-rhamnosyl glucoside, has variety of pharmacological effects, including anti-oxidant, anti-inflammatory, antibacterial, anticancer radioresistance effects. The current study focused on evaluation its anti-inflammatory activity described the mechanism rutin lipopolysaccharide-induced RAW 264.7 cells.The related gene protein expression levels were investigated by quantification...
Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have been proposed as a promising strategy for myocardial infarction (MI). This study aims to explore the mechanism of human umbilical cord MSCs (hucMSCs)-derived EVs loaded with miR-223 on MI. Inflammation, biological functions, and fibrosis in vitro were measured. Furthermore, MI rat models established verify role EVs-miR-223 vivo. The binding relationship between P53 was confirmed. ChIP assay utilized observe combination...
Abstract T cell is an indispensable component of the immune system and its multifaceted functions are shaped by distinct types their various states. Although multiple computational models exist for predicting abundance diverse types, tools assessing states to characterize degree resting, activation, suppression lacking. To address this gap, a robust nuanced scoring tool called state identifier (TCellSI) leveraging Mann–Whitney U statistics established. The TCellSI methodology enables...
Patients with premenopausal breast cancer (preBC) usually have long-term survivorship. However, less is known about the risk pattern of subsequent primary (SPC) and noncancer diseases among them. Here, this study aimed to evaluate developing SPCs mortality preBC survivors. In population-based, retrospective cohort study, 5-year survivors diagnosed at age 20-59 years during 1992-2014, in 11 Surveillance, Epidemiology End Result registries were included. Standardized incidence ratio (SIR)...
Although there are great changes of dietary in the past few decades China, known about aluminium exposure Chinese diet. The aim this study is to systematically evaluate intake level residents Shenzhen, China. A total 853 persons from 244 household were investigated their diet by three days food records. Finally, 149 kinds foods 17 groups selected be most consumed foods. From them, 1399 samples collected market test concentration. High levels found jellyfish (median, 527.5 mg/kg), fried...
Although the genotype–phenotype for familial medullary thyroid carcinoma (FMTC) is well studied, only few low susceptibility risk loci were identified non‐medullary (FNMTC). The aim of this study to screen and identify high‐penetrate genes FNMTC. A total 34 families with more than two first‐degree relatives diagnosed as papillary cancer without other syndrome recruited. Whole exome target gene sequencing performed candidate variants. These variants screened analyzed ESP6500, ExAC, 1000...
Abstract To explore the impact and mechanism of human mesenchymal stem cells (hMSCs) on angiogenesis cardiac microvascular endothelial (CMECs) after ischemia insult. Exosomes derived from hMSCs (hMSCs‐Exo) were identified by Western blotting labeled PHK‐67. CMECs isolated rat myocardial tissues. After hypoxic treatment, cultured with exosome inhibitor (GW4869) or transfected si‐COL4A1 + miR‐543 inhibitor. CMEC proliferation, migration, invasion, examined. Target genes predicted then dual...
Abstract Endothelial dysfunction is involved in various cardiovascular diseases such as atherosclerosis. progenitor cells (EPCs) contribute to re‐endothelialization and neo‐vascularization, the increase of EPCs peripherial circulation benefits prognosis disease. However, little known about biological stimuli that initiate proliferation maintenance stem cell phenotype EPCs. Here we reported human umbilical vein blood derived expressed gene transcripts coding for Toll‐like receptor (TLR) 1–6,...
Abstract The purposes of this study were to examine concentrations leptin and biochemical parameters in gestational diabetes mellitus (GDM) patients normal glucose tolerance (NGT) individuals also explore the links ( LEP ) G2548A receptor LEPR Gln223Arg polymorphisms with levels GDM risk among Chinese. Our included 357 355 NGT who at 24~30 weeks. Plasma insulin analyzed by ELISA. Gene genotyped using TaqMan real-time polymerase chain reaction assay. results showed that plasma significantly...
Abstract Aims Previous studies reported that histamine H2 receptor antagonists (H2RAs) had cardioprotective effects. However, the effect of H2RAs on mortality critical ill patients with heart failure (HF) remains unclear. The aim this study was to clarify association between and all-cause HF based Medical Information Mart for Intensive Care III database (MIMIC-III). Methods results Propensity score matching (PSM) applied account baseline differences two groups were exposed or not. primary...
A copper-catalyzed silylation of propargyl carbonates with silylboranes affords structurally diverse allenylsilanes including tri- or tetra-substituted and 1,1- 1,3-disubstituted allenylsilanes.