Xiaoying Lin

ORCID: 0000-0001-9581-280X
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About
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Research Areas
  • Wound Healing and Treatments
  • Stroke Rehabilitation and Recovery
  • Antimicrobial Resistance in Staphylococcus
  • Venous Thromboembolism Diagnosis and Management
  • Urticaria and Related Conditions
  • Surgical Sutures and Adhesives
  • Acute Ischemic Stroke Management
  • Thyroid and Parathyroid Surgery
  • Therapeutic Uses of Natural Elements
  • Thyroid Cancer Diagnosis and Treatment
  • Angiogenesis and VEGF in Cancer
  • Systemic Lupus Erythematosus Research
  • Orthopedic Infections and Treatments
  • Autoimmune Bullous Skin Diseases
  • Hemostasis and retained surgical items
  • Extracellular vesicles in disease
  • Reconstructive Surgery and Microvascular Techniques
  • Surgical site infection prevention
  • Plant responses to water stress
  • Bone Metabolism and Diseases
  • Digital Imaging in Medicine
  • Autophagy in Disease and Therapy
  • Hearing, Cochlea, Tinnitus, Genetics
  • Nasolacrimal Duct Obstruction Treatments
  • TGF-β signaling in diseases

Hainan Medical University
2024

Zhejiang University
2023-2024

Fujian Medical University
2021-2024

Fujian Provincial Hospital
2016-2024

Fuzhou University
2024

Jilin Medical University
2021-2024

Sir Run Run Shaw Hospital
2023-2024

Jinan University
2023-2024

Xian Yang Central Hospital
2023

Kunming Medical University
2020-2022

Vitamin E is one of the most widely used vitamins. In classical commercial synthesis vitamin (α-tocopherol), chemical isophytol key technical barrier. Here, we establish a new process for from microbial fermented farnesene. To achieve an efficient pathway farnesene production, Saccharomyces cerevisiae was selected as host strain. First, β-farnesene synthase genes different sources were screened, and through protein engineering system metabolic engineering, high production in S. achieved...

10.1016/j.xinn.2022.100228 article EN cc-by-nc-nd The Innovation 2022-03-12

Hemorrhage and infection of wounds are major causes death; hence, the development hemostasis materials with antibacterial properties is significant importance. In this study, a composite hydrogel (OSA/Gel/HNTs) was designed through one-step approach by using oxidized sodium alginate (OSA) gelatin as matrix halloysite nanotubes (HNTs) nanofillers in presence borax. The interactions among HNTs, OSA, were analyzed Fourier-transform infrared spectroscopy (FTIR) microscopic morphology. By...

10.1021/acssuschemeng.4c03668 article EN ACS Sustainable Chemistry & Engineering 2024-07-24

The incidence of chronic diabetic wounds is increasing with the growing number patients, and conventional wound dressings have proven to be ineffective in treating them. To address this challenge, researchers developed artificial dermal substitutes using collagen hyaluronic acid, which are crucial extracellular matrices. However, these subsitiues lack precision targeted treatment. overcome limitation, a gene liposome nanocomplex-loaded substitute (GDS) has been as potential solution. This...

10.1016/j.biopha.2023.114794 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2023-04-28

Early B cell factor 1 (EBF1) has been identified as an upstream transcription of the potential oncogene PNO1 and is involved in growth colorectal cancer (CRC) cells. However, its expression, biological function, underlying mechanism action most solid tumors remain largely unknown. We postulated that EBF1 a role pathophysiology CRC. Analysis mRNA expression CRC tumor samples from several public databases directly banked tissues revealed lower tissue compared to non-cancerous tissue. Survival...

10.3389/fonc.2020.01035 article EN cc-by Frontiers in Oncology 2020-06-26

To identify the risk factors for cervical lymph node metastasis (CLNM) and feasibility of prophylactic central dissection. The characteristics 1107 patients were extracted analyzed. Univariate multivariate analyses used to associated with metastasis. relationship between dissection (CLND) lateral (LLNM) was analyzed using correlation analysis. probability CLNM closely related male gender, age <55, increase tumor size. Those an in size extremely prone LLNM. Also, LLNM more likely happen those...

10.1155/2021/6635686 article EN cc-by International Journal of Endocrinology 2021-01-31

Background: Supersaturating drug delivery systems (SDDSs) have gained significant attention as a promising strategy to enhance the solubility and bioabsorption of Biopharmaceutics Classification System (BCS) II drugs. To overcome challenges associated with polymer-based amorphous SDDS (aSDDS), coamorphous (CAM) emerged viable alternative. Among them, “drug-drug” CAM (ddCAM) show considerable potential for combination therapy. However, many drugs in their pure forms are unstable at room...

10.3390/pharmaceutics16121488 article EN cc-by Pharmaceutics 2024-11-21

miRNA is involved in the occurrence and progression of systemic lupus erythematosus (SLE), but regulatory effect on dendritic cells SLE patients still unclear.Bioinformatics methods were used to analyze differentially expressed its target genes patients. In vitro experiments conducted explore effects mechanisms miRNAs differentiation maturation monocyte-derived cells.Bioinformatics analysis showed that miR-564 was up-regulated patients, TP53 core gene miR-564. The expression level a rising...

10.1177/09612033211020367 article EN Lupus 2021-05-27

Aim: The aim of the present study was to investigate effect mobilization EPCs by AMD3100 combined with G-CSF on wound healing in diabetic mice. Methods: full-thickness excisional wounds model mice (db/db) examined hematoxylin and eosin staining, immunohistochemical western blotting compare neovascularization among combination, alone, control groups. Results: reached complete closure groups days 17, 20, 21, 21 after surgery, respectively. In addition, combination group promoted inflammatory...

10.1177/14791641211002473 article EN cc-by-nc Diabetes and Vascular Disease Research 2021-03-01

Perovskite nanomaterials (NMs) possess excellent physicochemical properties and have promising applications in light-emitting diodes (LEDs), lasers, photodetectors, artificial synapse electronics. Potential exposure to these NMs happens the manufacture application of perovskite-based products, however, biological safety is still unknown. Here, we used LaNiO 3 NM (LNO), a typical kind perovskite nanostructures study interaction with macrophages (J774A.1) explore its effects at cellular level....

10.3389/fimmu.2021.676773 article EN Frontiers in Immunology 2021-04-22

The clamshell isothermal nucleic acid amplification analyzer RTisochip-S, a next-generation instrument featuring improved structural design, enhanced functional integration, reduced cost, and increased portability, was assessed for its suitability in clinical respiratory pathogens detection.

10.1016/j.plabm.2024.e00394 article EN cc-by-nc-nd Practical Laboratory Medicine 2024-04-16

To compare the safety and efficacy of ultrasound-guided radiofrequency ablation (RFA) in treatment T1N0M0 papillary thyroid carcinoma (PTC) with adjacent non-adjacent danger triangle area (DTA).

10.1080/02656736.2024.2419904 article EN cc-by International Journal of Hyperthermia 2024-10-28
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