A5036181157- Advanced Nanomaterials in Catalysis
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Nanocluster Synthesis and Applications
- SARS-CoV-2 and COVID-19 Research
- Autophagy in Disease and Therapy
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Antimicrobial agents and applications
- Advancements in Transdermal Drug Delivery
- Extracellular vesicles in disease
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Materials Characterization Techniques
- Advanced MRI Techniques and Applications
- Advanced Electron Microscopy Techniques and Applications
- Toxin Mechanisms and Immunotoxins
- Traditional Chinese Medicine Analysis
- Air Quality Monitoring and Forecasting
- Particle accelerators and beam dynamics
- Lipid Membrane Structure and Behavior
- Oral microbiology and periodontitis research
- Cancer Research and Treatments
- Characterization and Applications of Magnetic Nanoparticles
Queen's University Belfast
2025
National Center for Nanoscience and Technology
2019-2024
Institute of High Energy Physics
2019-2024
University of Chinese Academy of Sciences
2019-2024
University of Hong Kong
2021-2024
Chinese Academy of Sciences
2021-2024
Abstract How soft corona, the protein corona’s outer layer, contributes to biological identity of nanomaterials is largely because capturing composition corona in situ remains challenging. We herein develop an Fishing method that can monitor dynamic formation on ultra-small chiral Cu 2 S nanoparticles (NPs) allowing us directly separate and identify composition. Our detects spatiotemporal processes evolution hard coronas NPs, revealing subtle differences NP − interactions even within several...
During biomedical applications, nanozymes, exhibiting enzyme-like characteristics, inevitably come into contact with biological fluids in living systems, leading to the formation of a protein corona on their surface. Although it is acknowledged that molecular adsorption can influence catalytic activity there dearth understanding regarding impact nanozyme and its determinant factors. In order address this gap, we employed AuNR@Pt@PDDAC [PDDAC, poly(diallyldimethylammonium chloride)] nanorod...
Periodontitis is a chronic inflammatory disease caused by the interaction of oral microorganisms with host immune response. Porphyromonas gingivalis (P.g.) acts as key mediator in subverting homeostasis local system. On one hand, P.g. inhibits phagocytosis and killing capacity cells. other increases selective cytokine release, which beneficial to its further proliferation. Here, we prepared penetrating macrophage-based nanoformulation (MZ@PNM)-encapsulating hydrogel (MZ@PNM@GCP) that...
Enfuvirtide, the inaugural biomimetic fusion inhibitor of HIV-1, has exhibited remarkable antiviral efficacy when administered in conjunction with an optimized antiretroviral regimen. Nonetheless, high incidence (98%) injection site reactions associated twice-daily subcutaneous administration severely compromises patient adherence and long-term therapeutic outcomes. This study proposes hydrogel-forming microneedles (MNs) as a minimally invasive painless modality for transdermal delivery this...
Induction of immunogenic cell death (ICD) by hyperthermia can initiate adaptive immune responses, emerging as an attractive strategy for tumor immunotherapy. However, ICD induce proinflammatory factor interferon-γ (IFN-γ) production, leading to indoleamine 2,3-dioxygenase 1 (IDO-1) activation and immunosuppressive microenvironment, which dramatically reduces the ICD-triggered immunotherapeutic efficacy. Herein, we developed a bacteria-nanomaterial hybrid system (CuSVNP20009NB) systematically...
As a representative transition metal, iron plays key role in chemical activities of atmospheric particulate matter (PM), being involved particle-related free radical generation and adverse health effects. However, limited understanding the structure properties individual micrometer-sized particulates obscures investigating contributions toward activities. Here, we describe multidimensional analytical strategies to characterize mass, spatial distribution, forms single haze particles using...
With the increasing development and applications of catalytic biomedical nanomaterials (CBNMs), fundamental questions, including how biological microenvironment influences activity what are behaviors fates CBNMs in vitro vivo, have attracted attention scientists. To address these powerful analytical techniques gradually employed to demonstrate situ dynamic chemical information at different levels. Herein, we first introduce factors regulating activity. We then detail methods for that focus...
Phosphatase-like nanozyme LNO specifically induces macrophage autophagy, improving antitumor immunity. Pre-coating with myeloid cell membranes further enhances this effect, demonstrating significant therapeutic efficacy in vivo .
Perovskite nanomaterials (NMs) possess excellent physicochemical properties and have promising applications in light-emitting diodes (LEDs), lasers, photodetectors, artificial synapse electronics. Potential exposure to these NMs happens the manufacture application of perovskite-based products, however, biological safety is still unknown. Here, we used LaNiO 3 NM (LNO), a typical kind perovskite nanostructures study interaction with macrophages (J774A.1) explore its effects at cellular level....
Abstract The global emergency caused by the SARS-CoV-2 pandemics can only be solved with adequate preventive and therapeutic strategies, both currently missing. electropositive Receptor Binding Domain (RBD) of spike protein abundant β-sheet structure serves as target for COVID-19 drug design. Here, we discovered that ultrathin 2D CuInP 2 S 6 (CIPS) nanosheets a new agent against infection, which also able to promote viral host elimination. CIPS exhibits extremely high selective binding...