A5077224638- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Genital Health and Disease
- Urinary Tract Infections Management
- Research on Leishmaniasis Studies
- Dermatological and COVID-19 studies
- Cancer and Skin Lesions
- Autoimmune and Inflammatory Disorders
- Pelvic floor disorders treatments
- Poxvirus research and outbreaks
- Eosinophilic Disorders and Syndromes
- Cervical Cancer and HPV Research
- Dermatology and Skin Diseases
- Herpesvirus Infections and Treatments
- Parvovirus B19 Infection Studies
- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Bacterial Infections and Vaccines
- Bacillus and Francisella bacterial research
- Urological Disorders and Treatments
- Medicine and Dermatology Studies History
- Urologic and reproductive health conditions
- Urticaria and Related Conditions
Policlinico S.Orsola-Malpighi
2017-2025
University of Bologna
2015-2025
Azienda USL di Bologna
2022-2025
Ospedale Infermi di Rimini
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021
University of Washington
2017
Abstract We characterized the vaginal ecosystem during common infections of female genital tract, as vulvovaginal candidiasis (VVC, n = 18) and Chlamydia trachomatis infection (CT, 20), recruiting healthy (HC, 21) bacterial vaginosis-affected (BV, 20) women references eubiosis dysbiosis. The profiles microbiome metabolome were studied in 79 reproductive-aged women, by means next generation sequencing proton based-nuclear magnetic resonance spectroscopy. Lactobacillus genus was profoundly...
Syphilis has resurged globally, especially in urban areas of developed countries. This study analyses syphilis cases over a decade at an STD centre Bologna, Italy, examining new diagnoses, reinfections, and impacts on high-risk subgroups, compared with national European data. Data from 2009–2019 were retrospectively reviewed, including primary, secondary, early latent, late indeterminate cases, as per WHO guidelines. Cases tertiary serological-only diagnoses excluded. Statistical analysis...
While medical therapies are the mainstay for early stages, treating advanced hidradenitis suppurativa (HS) poses challenges due to frequent recurrence of lesions, which often requires wider surgical excisions [1]. This can lead delayed wound healing, an increased risk complications and scarring, significant patient discomfort, creating a notable barrier management [2]. Carbon dioxide (CO2) laser treatment has proven be effective modality reducing improving outcomes compared traditional...
Background Surveillance of human leishmaniasis in Europe is mostly limited to country-specific information from autochthonous infections the southern part. As at end 2021, no integrated analysis has been performed for cases seen across centres different European countries. Aim To provide a broad perspective on and imported endemic non-endemic countries Europe. Methods We retrospectively collected records cutaneous, mucosal visceral diagnosed 15 between 2014 2019. Centres were located 11...
Background Human leishmaniasis is a protozoan disease transmitted by sand flies and endemic in the Mediterranean region. In Italy, present south western coastal regions, with an epidemic peak detected northern Italy early 1970s. Aim To examine temporal trends, demographic, clinical, geographical environmental features of human cases recorded local health unit (LHU) Bologna, Italy. Methods this retrospective observational study, we analysed from 2004 to 2022 within Bologna LHU. We also...
The vaginal microbiota plays a crucial role in maintaining the health and functioning of female genital tract, preventing colonization urogenital pathogens sexually transmitted infections. In this study, we characterized bacterial communities metabolome associated to Chlamydia trachomatis infection (CT: 20 women), compared healthy condition (H: 22 women) vaginosis (BV: 19 women). A microarray-based tool (VaginArray), implemented with real-time PCR for Gardnerella vaginalis, was used...
Syphilitic alopecia (SA) is mainly described in single case reports, and there are only a few epidemiological studies.To investigate the clinical dermoscopic features of SA patients with secondary syphilis to record its actual prevalence.All diagnosis were clinically trichoscopically evaluated search hair scalp alterations.Five 12 (41.6%) diagnosed had SA. The 'moth-eaten' pattern was detected 4 (80% cases): 1 'essential' SA, whereas 3 'symptomatic' 'diffuse' found patient. Trichoscopy areas...
Monkeypox infection is a zoonosis first described in humans 1970 Congo. While previously manifesting small, confined outbreaks, the disease rapidly spreading globally. The aim of this study was to investigate microbiological samples (skin, rectal, and oropharyngeal swab plasma urine samples) that can help adequate diagnostic, therapeutic, prognostic management. We present 30 laboratory-confirmed monkeypox patients with peculiar clinical virological features admitted Sexually Transmitted...
Scabies infestation, caused by the Sarcoptes scabiei mite, has recently emerged as a public health concern in Western nations, with increased incidence worldwide. In Bologna, Italy, local authorities report rise scabies diagnoses, although detailed data are limited. This study aimed to analyse temporal trends of cases diagnosed at S. Orsola Hospital's Dermatological Emergency Department, focusing on significant changes and seasonal variation over time. A retrospective observational was...
Abstract: We report here a new case of neutrophilic figurate erythema infancy in 1‐year and 9‐month‐old white boy. Neutrophilic is rare inflammatory dermatosis which part the dermatoses considered variant annular infancy. The disease clinically characterized by erythematous lesions, sometimes with polycyclic configuration, histologically dermal infiltration leukocytoclasia. Differential diagnosis mainly includes clear‐cut severe diseases well‐known etiology, such as neonatal lupus...
Background Although syphilis rates have been relatively high in Italy for more than 15 years, no data on the molecular types of Treponema pallidum subspecies circulating this country are yet available. Likewise, how widespread is resistance to macrolide or tetracycline antibiotics these strains exist. Such would, however, promote comprehensive studies epidemiology infections and inform future interventions aiming at control other European countries. Goals Study Design Swabs from oral,...
We assessed the prevalence and predictors of Chlamydia trachomatis, Neisseriagonorrhoeae Mycoplasmagenitalium rectal infections in a population 'men having sex with men' (MSM).From January to November 2017, 165 MSM attending STI outpatients clinic Bologna (Italy) reporting unsafe anal intercourses were enrolled. An ano-rectal swab was collected from each patient: chlamydial gonococcal diagnosed by commercial NAAT, whereas an in-house quantitative PCR used for M. genitalium detection. In...
The aim of this study was to characterize the urine metabolome women with Chlamydia trachomatis (CT) uro-genital infection (n = 21), comparing it a group CT-negative subjects 98). By means proton-based nuclear magnetic resonance (1H-NMR) spectroscopy, we detected and quantified metabolites cohort 119 pre-menopausal Caucasian women, attending STI Outpatients Clinic in Italy. In case CT positive result, molecular genotyping performed by omp1 gene semi-nested PCR followed RFLP analysis. We were...
Commensal Neisseria species of the oropharynx represent a significant reservoir antimicrobial resistance determinants that can be transferred to gonorrhoeae . This aspect is particularly crucial in ‘men having sex with men’ (MSM), key population which pharyngeal co-colonization by N. and non-pathogenic frequent associated emergence resistance. Here, we explored susceptibility large panel isolated from two populations: group MSM attending ‘sexually transmitted infection’ clinic Bologna...
Background In triple negative breast cancer patients treated with neoadjuvant chemotherapy, residual disease at surgery is the most relevant unfavorable prognostic factor. Current guidelines consider use of adjuvant capecitabine, based on results randomized CREATE-X study, carried out in Asian and including a small subset tumors. Thus far, evidence Caucasian limited, no real-world data are available. Methods We multicenter, observational involving 44 oncologic centres. Triple disease,...
Objectives Lymphogranuloma venereum (LGV) is an STI caused by Chlamydia trachomatis serovars L1-L3. In Europe, the current epidemic mainly L2b genovariant, although increasing cases associated with other L2 variants have been reported. Here, we assessed distribution of rectal LGV genovariants among men having sex (MSM) in Italy. Methods From 2016 to 2020, all anorectal swabs collected from MSM attending Clinic St. Orsola-Malpighi Hospital Bologna and positive for C. were stored. infection...
(CT) is the agent of most common bacterial sexually transmitted infection worldwide, with a significant impact on women's health. Despite increasing number studies about vaginal microbiome in women CT infections, information composition anal still lacking. Here, we assessed community profiles and ecosystems associated or not cohort Caucasian young women.