We have developed a simple and direct method to fabricate paper-based microfluidic devices that can be used for wide range of colorimetric assay applications. With these devices, assays performed within minutes allow quantitative analysis by use widely accessible iPhone camera an RGB color reader application (app) measure intensity. In the described laboratory experiment, students design create their own with common supplies such as Kimwipes, Parafilm, thermal laminator, gain hands-on...

A sensitive, selective, environmentally friendly, high-throughput, well-plate-based immunosorbent assay was developed to detect human α-fetoprotein (AFP) using carbon dots (C-Dots). Highly fluorescent C-Dots were synthesized a one-step hydrothermal reaction, with citric acid serving as the source and ethylene diamine acting nitrogen source. The reaction conditions optimized obtain desired surface functionality. Then, used label one member of anti-AFP pair (Ab2) via amine-amine coupling...

Panchromatic sharpening (pansharpening) is an important technology for improving the spatial resolution of multispectral (MS) images. The majority models are implemented at reduced resolution, leading to unfavorable results full resolution. Moreover, complicated relationship between MS and panchromatic (PAN) images often ignored in detail injection. For mentioned problems, unsupervised generative adversarial networks with recursive mixed-scale feature fusion pansharpening (RMFF-UPGAN)...

Non-toxic, fluorescent carbon nanodot labels are employed as novel ratiometric immunosensors for α-fetoprotein (AFP), a liver cancer biomarker. The assay generates broad linear range, low detection limit, and can be adapted to variety of immunoassay targets.

Rhizoma Anemarrhenae, a famous traditional Chinese medicine (TCM), is the dried rhizome of Anemarrhena asphodeloides Bge. (Anemarrhena Bunge Liliaceae). The presents anti-inflammatory, antipyretic, sedative, and diuretic effects. chemical constituents Anemarrhenae are complex diverse, mainly including steroidal saponins, flavonoids, phenylpropanoids, benzophenones, alkaloids. In this study, UPLC-Q-TOF/MS was used in combination with data postprocessing techniques, characteristic fragments...

Fingerprinting is widely and commonly used in the quality control of traditional Chinese medicine (TCM) injections. However, current studies informed that fingerprint similarity evaluation was less sensitive easily generated false positive results. For this reason, a novel practical chromatographic "Fingerprint-ROC-SVM" strategy established by using KuDieZi (KDZ) injection as case study present article. Firstly, fingerprints KDZ were obtained UPLC common characteristic peaks identified with...

Purpose This paper aims to improve the generalization capability of feature extraction scheme by introducing a micro-cracks detection method based on self-learning features. Micro-cracks multicrystalline solar cell surface machine vision is fast, economical, intelligent and easier for on-line detection. However, adopted existed methods limited, which has become an obstacle further improving accuracy. Design/methodology/approach A novel features low-rank matrix recovery proposed in this...

A convenient, economical SILLME method coupled with HPLC/FLD for sample preparation, extraction and trace-level quantitative determination of fluoroquinolones is reported.

Simiao Wan (SMW), an important multiherbal formula used in traditional Chinese medicine, is extensively to treat rheumatoid arthritis. However, the knowledge of bioactive components SMW remains unclear. Thus, gas chromatography–mass spectrometry (GC‐MS) and liquid (LC‐MS) were analyze chemical constituents volatile nonvolatile extracts SMW, as well its absorbed rat plasma after oral administration. Identification several compounds was enabled by comparison retention times, MS spectra, MS/MS...

Multispectral (MS) pansharpening is crucial to improve the spatial resolution of MS images. has potential provide images with high and spectral resolutions. Pansharpening technique based on deep learning a topical issue deal distortion spatio-spectral information. To preservation information, we propose novel three-stage detail injection network (TDPNet) for remote sensing First, put forward dual-branch multiscale feature extraction block, which extracts four scale details panchromatic (PAN)...

An ethyl acetate-assisted ionic liquid dispersive liquid–liquid microextraction method was developed for the determination of tetracyclines in water samples with high-performance chromatography using a variable wavelength detector. A mixture acetate and 1-butyl-3-methylimidazolium hexafluorophosphate used to isolate lanthanum(III) chelates tetracyclines. The addition significantly enhanced extraction efficiencies. Experimental parameters affecting efficiency such as identity volume liquid,...

Described is a new approach to building microfluidic quantum dot wavelength-ratiometric sensor system for quantifying copper in water and biological samples.

The hardness recognition is of great significance to tactile sensing and robotic control. methods based on deep learning have demonstrated its good performance, however, a huge amount manually labeled samples which require lots time labor costs are necessary for the training neural networks. In order alleviate this problem, semi-supervised generative adversarial networks (GAN) requires less proposed in paper. First all, large number unlabeled made use through unsupervised GAN used provide...

A novel approach to building a membrane-based disposable well-plate, here applied cyanide detection, is described. Chitosan encapsulated CdTe quantum dots with maximum emission at 520 nm (CS-QD520) were used as fluorophores. The CS-QD520 nanoparticle was specifically quenched by copper(II), and the (Cu-CS-QD520) deposited onto glass microfiber filter (GF/B). Subsequent introduction of ion resulted in fluorescence recovery. "signal-ON" linearly correlated concentrations range 38.7 200 μM...

Remote sensing images have been widely applied in various industries; nevertheless, the resolution of such is relatively low. Panchromatic sharpening (pan-sharpening) a research focus image fusion domain remote sensing. Pan-sharpening used to generate high-resolution multispectral (HRMS) making full use low-resolution (LRMS) and panchromatic (PAN) images. Traditional pan-sharpening has problems spectral distortion, ringing effect, low resolution. The convolutional neural network (CNN)...