A5060220420- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Pulmonary Hypertension Research and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiovascular Disease and Adiposity
- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Cardiac Imaging and Diagnostics
- Trauma Management and Diagnosis
- Coronary Interventions and Diagnostics
- Genetics, Bioinformatics, and Biomedical Research
- Cardiac Arrest and Resuscitation
- Obstructive Sleep Apnea Research
- Hemoglobin structure and function
- Traumatic Brain Injury and Neurovascular Disturbances
- Ultrasound in Clinical Applications
- Oropharyngeal Anatomy and Pathologies
- Lipoproteins and Cardiovascular Health
- Cerebral Venous Sinus Thrombosis
- Trigeminal Neuralgia and Treatments
- Foreign Body Medical Cases
Sunnybrook Health Science Centre
2012-2025
Health Sciences Centre
2009-2025
Sunnybrook Research Institute
2024-2025
University of Toronto
2015-2025
John Brown University
2025
Trillium Health Centre
2024
Charing Cross Hospital
2024
Brown University
2021-2024
Kathmandu University
2024
University Health Network
2020-2024
To investigate the association between magnetic resonance (MR) imaging-depicted intraplaque hemorrhage (IPH) in carotid artery wall and risk of future ipsilateral cerebrovascular events men with asymptomatic moderate stenosis by using a rapid three-dimensional T1-weighted fat-suppressed spoiled gradient-echo sequence.The institutional ethics review board approved this retrospective chart waived requirement for written informed consent. All patients gave verbal consent at follow-up telephone...
We sought to evaluate the effect of weight loss on echocardiographic epicardial fat thickness, as index visceral adiposity, and whether change after can be proportionally different from overall body changes related cardiac parameters in severely obese subjects. This was an interventional study 20 subjects (12 women, 8 men, BMI 45+/-5 kg/m(2), 35+/-10 years) who underwent 6-month very low calorie diet program. Baseline anthropometrics, left ventricular mass (LVM), diastolic function were...
Three different methods for estimating the percentage of reduction in diameter internal carotid artery (ie, stenosis) have been proposed literature. Further comparisons were carried out with intent recommending a current standard determining stenosis from angiograms. Angiograms 112 patients obtained. For each angiogram, was estimated manner European Carotid Surgery Trial (ECST method), North American Symptomatic Endarterectomy (NASCET and by method using common lumen (CC method). Although...
Quantum Machine Learning (QML) offers significant potential for complex tasks like genome sequence classification, but quantum noise on Noisy Intermediate-Scale (NISQ) devices poses practical challenges. This study systematically evaluates how various models including dephasing, amplitude damping, depolarizing, thermal noise, bit-flip, and phase-flip affect key QML algorithms (QSVC, Peg-QSVC, QNN, VQC) feature mapping techniques (ZFeatureMap, ZZFeatureMap, PauliFeatureMap). Results indicate...
Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models binary classification genome sequence data by employing various feature mapping techniques. We present an open-source, independent Qiskit-based implementation conduct experiments on a benchmark genomic dataset. Our simulations reveal that interplay between techniques algorithms significantly influences...
Visceral adipose tissue predicts an unfavorable cardiovascular and metabolic risk profile in humans. Existing methods to assess visceral have been limited. Thus, echocardiographic assessment of epicardial as a marker adiposity was suggested. The technique has shown be very reliable method excellent measure adiposity. In this article, tissue's localization on the heart, function, reliability is briefly reviewed. Areas requiring further study are identified.
To determine if complicated plaque can be found by using magnetic resonance (MR) imaging-depicted intraplaque hemorrhage (IPH), even among symptomatic patients with low-grade (≤50%) carotid stenosis.The institutional ethics review board approved this retrospective study and waived requirements for written informed consent. Symptomatic bilateral 0%-50% stenosis referred MR imaging were considered. Risk factors (age, sex, hypertension, diabetes, hyperlipidemia, myocardial infarction, atrial...
Stroke rates are higher in men compared with women the fourth through seventh decades of life, and may result from differences carotid intraplaque hemorrhage (IPH), an unstable atherosclerotic plaque component. We report age-specific sex presence magnetic resonance imaging-depicted IPH.Patients (n=1115) underwent imaging for IPH between 2005 2014. Low-grade stenosis patients (n=906) without prior endarterectomy were eligible this cross-sectional study.Of 906 included (mean age±SD years,...
Abstract Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes, progression and pathogenesis. We aimed further validate our previously described method propagate right heart catheter (RHC) balloon tips perform additional PAEC phenotyping. performed bulk RNA sequencing PAECs RHC balloons. Using unsupervised...
Foreign body aspiration can infrequently occur following trauma. Tooth after trauma is a rare clinical scenario. Here, we report case in which tooth led to presentation of acute respiratory failure with findings mimicking tension pneumothorax. Successful removal the aspirated was accomplished by rigid bronchoscopy. must be considered list differential diagnosis for any patient having signs or symptoms distress especially maxillofacial
The coronavirus disease 2019 (COVID-19) pandemic has led to widespread changes in all health care settings including academic radiology departments. purpose of this survey-based study was investigate the impact COVID-19 on resident training and education workflow Canada terms nature, scale, heterogeneity changes, preparedness adaptation, perceptions present future training.A 30-question web-based survey sent 17 residency program directors across Canada. A separate 32-question 460 residents...
Preoperative detection of axillary lymph node metastases (ALNMs) from breast cancer is suboptimal; however, recent work suggests radiomics may improve ALNMs. This study aims to develop a 3D CT model ALNMs compared conventional imaging features in patients with locally advanced cancer.
Abstract Title. Emergency department equipment for obese patients: perceptions of adequacy Aim. This study reports an investigation to assess patients’ and nurses’ patients presenting at emergency knowledge weight limits in the department. Background. The increasing populations many societies is a challenge healthcare providers facilities. equipment, specifically, may be inadequate patient care. Methods. Two questionnaires were developed. One was administered 134 with suspected cardiac...
A 37-year-old woman presents to the emergency department four hours after an acute onset of "worst headache her life" that began at rest. She experienced no loss consciousness or neck pain. has history intracranial disease family cerebral aneurysms. Her vital