A5091719135- Impact of Technology on Adolescents
- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Digital Mental Health Interventions
- Genetic factors in colorectal cancer
- Cancer, Lipids, and Metabolism
- Child Development and Digital Technology
- Eating Disorders and Behaviors
- Ovarian cancer diagnosis and treatment
- Advanced Photocatalysis Techniques
- RNA modifications and cancer
- Inflammatory mediators and NSAID effects
- Cholesterol and Lipid Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- EEG and Brain-Computer Interfaces
- Mind wandering and attention
- Dementia and Cognitive Impairment Research
- Advanced Neuroimaging Techniques and Applications
- Cancer, Stress, Anesthesia, and Immune Response
- Behavioral Health and Interventions
- Neural and Behavioral Psychology Studies
- Cancer-related cognitive impairment studies
- Soft Robotics and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Intensive Care Unit Cognitive Disorders
Shanghai Mental Health Center
2019-2025
Shanghai Jiao Tong University
2016-2025
Shijiazhuang Yiling Pharmaceutical (China)
2025
Shanghai Sixth People's Hospital
2025
Shaoxing University
2024
Dalian University
2024
Dalian University of Technology
2024
Ministry of Public Security of the People's Republic of China
2024
Nantong University
2024
Hangzhou Normal University
2019-2023
The amyloid precursor protein (APP) of Alzheimer's disease can reduce copper (II) to (I) in a cell-free system potentially leading increased oxidative stress neurons. We used neuronal cultures derived from APP knock-out (APP(-/-)) and wild-type (WT) mice examine the role neurotoxicity. WT cortical, cerebellar, hippocampal neurons were significantly more susceptible than their respective APP(-/-) toxicity induced by physiological concentrations but not zinc or iron. There was no difference...
Abstract There is an emergent literature suggesting that East Asians and Westerners differ in cognitive processes because of cultural biases to process information holistically (East Asians) or analytically (Westerners). To evaluate the possibility such differences are accompanied by brain structure, we conducted a large comparative study on cognitively matched young old adults from two cultural/ethnic groups—Chinese Singaporeans non-Asian Americans—that involved total 140 persons. Young...
To investigate the contribution of sleep duration and quality to age-related changes in brain structure cognitive performance relatively healthy older adults. Community-based longitudinal aging study using a convenience sample. Participants were studied research laboratory. Relatively adults aged 55 y at commencement. N/A. underwent magnetic resonance imaging neuropsychological assessment every 2 y. Subjective assessments blood samples obtained. Each hour reduced baseline augmented annual...
We determined if sleep deprivation would amplify the effect of negative emotional distracters on working memory. A crossover design involving 2 functional neuroimaging scans conducted at least one week apart. One scan followed a normal night and other 24 h deprivation. Scanning order was counterbalanced across subjects. The study took place in research laboratory. young, healthy volunteers with no history any sleep, psychiatric, or neurologic disorders. N/A Study participants were scanned...
The link between central adiposity and cognition has been established by indirect measures such as body mass index (BMI) or waist-hip ratio. Magnetic resonance imaging (MRI) quantification of abdominal fat linked to elevated risk cardiovascular cerebro-vascular disease. However it is not known how visceral correlates with cognitive performance brain structure. We filled this gap characterizing the relationships MRI adiposity, morphometry, cognition, in healthy elderly.A total 184 community...
Although East Asia harbors the largest number of aging adults in world, there is currently little data clarifying longitudinal brain-cognition relationships this group. Here, we report structural MRI and neuropsychological findings from relatively healthy Chinese older Singapore-Longitudinal Aging Brain Study cohort over 8 years follow up (n=111, mean age=67.1 years, range=56.1-83.1 at baseline). Aging-related change volume was observed, with total cerebral atrophy -0.56%/year, hippocampal...
Online gaming has become a popular leisure activity, in which males more frequently develop Internet disorder (IGD) compared to females. However, gender-related neurocognitive differences have largely not been systematically investigated IGD.Cue-elicited-craving tasks were performed before game playing and immediately after deprivation operationalized as forced break from when the was disconnected. Ninety-nine subjects with IGD (27 22 females) or recreational use (RGU; 27 23 provided...
Abstract Background Studies of Internet gaming disorder (IGD) suggest an imbalanced relationship between cognitive control and reward processing in people with IGD. However, it remains unclear how these two systems interact each other, whether they could serve as neurobiological markers for Methods Fifty IGD subjects matched individuals recreational game use (RGU) were selected compared when performing a cue-craving task. Regions interests [anterior cingulate cortex (ACC), lentiform nucleus]...
The purpose of this study was to investigate the association between spontaneous regional activity and brain functional connectivity, which maybe can distinguish insomnia while being responsive repetitive transcranial magnetic stimulation (rTMS) treatment effects in patients.
There is cumulative evidence that young people in an "at-risk mental state" (ARMS) for psychosis show structural brain abnormalities frontolimbic areas, comparable to, but less extensive than those reported established schizophrenia. However, most available data come from ARMS samples Australia, Europe, and North America while large studies other populations are missing. We conducted a magnetic resonance imaging study relatively sample of 69 individuals 32 matched healthy controls (HC)...
An increasing number of people are becoming addicted to the internet as a result overuse. The Internet Addiction Test (IAT) is popular tool for evaluating use behaviors. interaction between different symptoms and relationship IAT clinical diagnostic criteria not well understood.This study aimed explore core addiction (IA) correlation IA symptom network. Network analysis was also conducted association scale Diagnostic Statistical Manual Mental Disorders-5th edition (DSM-5) IA.We recruited...
Develop a predicting model that can help stratify patients with epithelial ovarian cancer (EOC) before platinum-based chemotherapy. 148 pathologically confirmed EOC and minimum 5-year follow-up were retrospectively enrolled. Patients classified into platinum-sensitive platinum-resistant groups according to treatment responses. The correlation between clinical factors drug sensitivity was evaluated using statistical tests. Approximately 700,000 single-nucleotide polymorphism (SNP) sites...
Abstract Background Food addiction and an impulsive personality can increase overeating, which lead to weight gain. The amygdala nucleus accumbens (NAcc) are critical for regulating obesogenic behaviour. However, whether the or NAcc acts as neural basis regulation of food addiction, personality, body remains unclear. Methods We examined differences in volume NAcc, especially lateralization index (LI), between 33 obese participants 39 age- sex-matched healthy controls. associations LI each...
This study focuses on the impact of digital intelligent interior design user cognition and conducts a detailed empirical analysis. By reviewing trend technology in design, this paper reveals modern development direction field. Using research methods to collect preprocess relevant data, cognitive evaluation index system is constructed, role enhancing perception experience discussed. The results are great significance for understanding changes brought about by provide theoretical support...
Bus drivers face complex work challenges and high infection risks, particularly heightened during the COVID-19 pandemic, which significantly affects their mental health. This study used network analysis to conduct a longitudinal follow-up of psychological symptom bus drivers, utilizing Symptom Checklist-90-Revised (SCL-90-R). A repeated-measures self-controlled observational design was survey 1,600 intercity in city southern Anhui, China, September 2022 January 2023, respectively,...
<title>Abstract</title> Psychoticlike experiences (PLEs) are perceived as early indicators for the progression to schizophrenia spectrum disorders, a grave concern in psychiatric research. Historically, interconnectedness between positive and negative symptoms PLEs has remained enigmatic. In this multicenter cross-sectional study, we aim investigate relationship – crucial of transition disorders.Our sample includes 37,443 high school/college students from 19 cities across four Chinese...