A5068851774- History of Medicine Studies
- Drug-Induced Hepatotoxicity and Protection
- Natural Antidiabetic Agents Studies
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Garlic and Onion Studies
- Berberine and alkaloids research
- Metabolism and Genetic Disorders
- Medicinal Plant Extracts Effects
- Phytochemicals and Medicinal Plants
- Cholesterol and Lipid Metabolism
- Pharmacological Effects of Natural Compounds
- Ziziphus Jujuba Studies and Applications
- Ophthalmology and Visual Health Research
- Cardiac Ischemia and Reperfusion
- Nigella sativa pharmacological applications
- Health and Well-being Studies
- Pharmacological Effects and Toxicity Studies
- Medical History and Innovations
- Phytochemicals and Antioxidant Activities
- Eicosanoids and Hypertension Pharmacology
- Neuroscience of respiration and sleep
- Kidney Stones and Urolithiasis Treatments
- Saffron Plant Research Studies
- Pharmacology and Obesity Treatment
Arak University of Medical Sciences
2016-2025
Iran University of Medical Sciences
2025
Tehran University of Medical Sciences
2018
Islamic Azad University, Damghan Branch
2013
Islamic Azad University of Arsanjan
2012
Acute kidney injury induces the loss of renal microvessels, but fate endothelial cells and mechanism potential vascular growth factor (VEGF)-mediated protection is unknown. Cumulative cell proliferation was analyzed in Sprague-Dawley rats following ischemia-reperfusion (I/R) by repetitive administration BrdU (twice daily) colocalization with CD31 or cablin. Proliferating were undetectable for up to 2 days I/R accounted only ∼1% BrdU-positive after 7 days. VEGF-121 preserved did not affect...
This investigation examined the potential antibacterial and antidiabetic effects of wound dressings created using electrospun nanofibers containing Ziziphus jujuba fruit extract (ZJ). These were composed a combination Polycaprolactone (PCL), Polyvinyl Alcohol (PVA), Polyhexamethylene Biguanide (PHMB). The process creating these involved electrospinning. nanofiber products, which included PCL, PCL/PVA, PCL/PVA/ZJ, PCL/PVA/PHMB, PCL/PVA/PHMB/ZJ, underwent morphology, physicochemical,...
Inflammation is one of the major challenges in management ischaemia/reperfusion (I/R)-induced acute kidney injury. Our aim was to assess anti-inflammatory and protective effects saffron extract against I/R-induced renal disturbances.A total 35 male Wistar rats were randomly divided into five groups (n = 7) as sham, I/R three that pretreated with different doses (5 mg/kg, 10 or 20 mg/kg) intraperitoneally. The inflammation assessed by measuring leukocyte infiltration mRNA expression levels...
Mallow (Malva sylvestris L.) has had medicinal and therapeutic uses in addition to its oral consumption. The present study was conducted examine the protective effect of Malva L. extract on ischemia-reperfusion-induced kidney injury remote organ injuries liver. Before ischemia-reperfusion, rats different groups received intraperitoneal normal saline or mallow at doses 200, 400 600 mg/kg body weight. After 30-minutes bilateral renal ischemia followed by 24-hours reperfusion, tissue damage...
Gentamicin-induced nephrotoxicity was used as an experimental model of kidney disease. The present study performed to assess the therapeutic role cannabidiol (CBD) against gentamicin-induced renal damage.Forty two male Wistar rats were randomly allocated into 6 groups (n=7), including: (1) Control, (2) Vehicle, (3) Gentamicin-treated group (100 mg/kg/day) for 10 days (GM), (4-6) 3 Gentamicin-CBD-treated (2.5, 5, and (GM+CBD2.5, GM+CBD5, GM+CBD10). Serum levels BUN Cr, histology well...
: Melissa officinalis(lemon balm) which belongs to the Lamiaceae family is a known herb that has long been used in traditional medicine treat many disorders, and several studies have conducted identify plant its healing properties. The purpose of this article review series on effects extract function various body organs. Due volatile organic compounds active constituents such as terpenoids, flavonoids, quercetin, rutin, quercitrin, gallic acid high antioxidant capacity, can significant role...
Gentamicin (GM) is one of the commonest causes drug-induced nephrotoxicity. Moreover, oxidative stress plays an important role in gentamicin-induced The current study aimed to explore antioxidant and protective effects Pimpinella anisum (P. anisum) on alleviation GM-induced damage.Forty male wistar rats were divided into four groups: control, sham that was administrated normal saline orally intraperitoneally (i.p.), GM received 100 mg/kg bw/day i.p., ethanolic extract P. at oral dose 300 for...
Abstract Background and aim We recently showed that L ‐carnitine reduced oxidative stress suppressed energy metabolism, while α‐tocopherol only prevented redox imbalance, in the obstructed kidney of rats subjected to 24‐hr unilateral ureteral obstruction (UUO). The present study was undertaken investigate effects both compounds on disturbed renal hemodynamics, solutes‐excretion, urine‐concentrating ability as well metabolism at early hours following release UUO. Methods UUO induced...