Shohreh Fahimirad

ORCID: 0000-0002-9991-0869
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Electrospun Nanofibers in Biomedical Applications
  • Biochemical and Structural Characterization
  • Probiotics and Fermented Foods
  • Protein Hydrolysis and Bioactive Peptides
  • Wound Healing and Treatments
  • Silk-based biomaterials and applications
  • Nanoparticles: synthesis and applications
  • Antimicrobial agents and applications
  • Essential Oils and Antimicrobial Activity
  • Plant Stress Responses and Tolerance
  • Bee Products Chemical Analysis
  • Advanced Drug Delivery Systems
  • Graphene and Nanomaterials Applications
  • Proteins in Food Systems
  • Membrane Separation Technologies
  • Polysaccharides Composition and Applications
  • Advancements in Transdermal Drug Delivery
  • Tea Polyphenols and Effects
  • Flavonoids in Medical Research
  • Microplastics and Plastic Pollution
  • Genetic Mapping and Diversity in Plants and Animals
  • Membrane-based Ion Separation Techniques
  • Advanced Sensor and Energy Harvesting Materials
  • Phytochemistry Medicinal Plant Applications

Arak University of Medical Sciences
2020-2025

University of South Africa
2024

University of Tehran
2015-2019

Arak University
2017

Tarbiat Modares University
2013

Abstract Conventional cancer treatments can cause serious side effects because they are not specific to cells and damage healthy cells. Aptamers often single-stranded oligonucleotides arranged in a unique architecture, allowing them bind specifically target sites. This feature makes an ideal choice for targeted therapeutics. They typically produced through the systematic evolution of ligands by exponential enrichment (SELEX) undergo extensive pharmacological revision modify their affinity,...

10.1186/s12935-024-03295-4 article EN cc-by Cancer Cell International 2024-03-16

In this study, copper nanoparticles (CuNPs) were synthetized through green chemistry approach using C. officinalis flowers extract. The biosynthetized characterized by FESEM, XRD, DLS and FTIR analysis. Subsequently, PCL nanofiber was fabricated as first supportive layer electrospinning method. Afterward, PVA/Quercus infectoria galls (QLG) extracts/biosynthetized CuNPs blending solution electrospinned second bioactive topical layer. morphology, physicochemical properties biological...

10.1080/09205063.2022.2116209 article EN Journal of Biomaterials Science Polymer Edition 2022-08-22

This investigation examined the potential antibacterial and antidiabetic effects of wound dressings created using electrospun nanofibers containing Ziziphus jujuba fruit extract (ZJ). These were composed a combination Polycaprolactone (PCL), Polyvinyl Alcohol (PVA), Polyhexamethylene Biguanide (PHMB). The process creating these involved electrospinning. nanofiber products, which included PCL, PCL/PVA, PCL/PVA/ZJ, PCL/PVA/PHMB, PCL/PVA/PHMB/ZJ, underwent morphology, physicochemical,...

10.1080/09205063.2024.2384299 article EN Journal of Biomaterials Science Polymer Edition 2024-08-01

Antimicrobial peptide compounds (AMPs) play important roles in the immune system. They also exhibit significant anti-tumor and antibacterial properties. Most AMPs are cationic able to bind bacterial cell membranes through electrostatic affinity. Ib-AMP4 is a plant-derived AMP that exerts rapid bactericidal functions. In present study, efficiency of produced recombinant elimination Methicillin-resistant Staphylococcus aureus (MRSA) infection, was investigated under vitro vivo situations.The...

10.22038/ijbms.2022.61043.13508 article EN PubMed 2022-02-01

Accelerating emergence of antimicrobial resistance among food pathogens and consumers' increasing demands for preservative-free foods are two contemporary challenging aspects within the industry. Antimicrobial packaging use natural preservatives promising solutions. In present study, we used beta-casein-one primary self-assembly proteins in milk with a high polymeric film production capability-as fusion partner recombinant expression E 50-52 peptide Escherichia coli. The pET21a-BCN-E...

10.3390/molecules22060822 article EN cc-by Molecules 2017-05-31

Background: A highly effective antibacterial wound dressing was developed in this investigation by developing a novel bioactive functional nanostructure. Methods: Ethanolic extracts of propolis (EEP) and Q.infectoria galls (QIG) were processed to obtain their respective extracts. The properties the individual EEP QIG combined effects investigated. Based on test results, solutions containing polycaprolactone (PCL), PCL/EEP, PCL/QIG PCL/EEP/QIG prepared. These then used fabricate nanobased...

10.1142/s1793292024500747 article EN NANO 2024-05-10

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is known to be one of the most potentially pathogenic organisms in world. Skin infections are significant S. aureus. Therefore, therapeutic constraints have challenged researchers seek new strategies produce medicines. Antimicrobial peptides (AMPs) a generation natural drugs with antimicrobial properties and high fatality potency. Oncorhyncin II AMP group bacteriostatic activity effect against Gram-positive Gram-negative...

10.5812/jjm.95948 article EN Jundishapur Journal of Microbiology 2020-05-09

Background: The antimicrobial peptides (AMPs) played a critical role in the innate immunity of host and considered natural sources illustrating broad-spectrum activity with high specificity low cytotoxicity. AMPs generally possess net positive charge have amphipathic structures. Thus, can bind interact negatively charged bacterial cell membranes, leading to destructive defects biomembranes ending death. LL37 is only human cathelicidin-derived peptide which show broad spectrum activity....

10.2174/0929866529666220929160704 article EN Protein and Peptide Letters 2022-09-30
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