- Chalcogenide Semiconductor Thin Films
- Quantum Dots Synthesis And Properties
- Ultrasound and Hyperthermia Applications
- Copper-based nanomaterials and applications
- Hepatitis C virus research
- Cardiac Ischemia and Reperfusion
- Electrospun Nanofibers in Biomedical Applications
- Perovskite Materials and Applications
- Testicular diseases and treatments
- Hepatitis B Virus Studies
- Tissue Engineering and Regenerative Medicine
- Nitric Oxide and Endothelin Effects
- Gut microbiota and health
- Photonic and Optical Devices
- Monoclonal and Polyclonal Antibodies Research
- Semiconductor materials and interfaces
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Biochemical and Molecular Research
- Adipose Tissue and Metabolism
- Endoplasmic Reticulum Stress and Disease
- Medicinal Plants and Bioactive Compounds
- Ferroptosis and cancer prognosis
- Hernia repair and management
- Intensive Care Unit Cognitive Disorders
Wuhan University
2006-2025
Renmin Hospital of Wuhan University
2006-2025
Chongqing Public Health Medical Center
2025
Chongqing Medical University
2025
Nanchang University
2008-2024
Hebei University
2021-2024
Fujian Medical University
2014-2024
Peking University
2002-2024
Beijing University of Chinese Medicine
2022-2024
Henan University
2021-2024
This study aimed to investigate the effect of bone marrow mesenchymal stem cell (BMSC)-derived exosome injection on cartilage damage and pain relief in both vitro vivo models osteoarthritis (OA).The BMSCs were extracted from rat femur tibia. Chondrocytes treated with IL-1β establish model OA. Chondrocyte proliferation migration assessed by CCK-8 transwell assay, respectively. A OA was established sodium iodoacetate. At 6 weeks after established, knee joint specimens dorsal root ganglion...
Abstract The unsatisfactory material quality of absorber is an important factor limiting the development Cu 2 ZnSn(S,Se) 4 (CZTSSe) thin‐film solar cells, including poor crystallization, multi‐layer structure, and various defects. Here, effective strategy to enhance kesterite improve performance cells proposed by tailoring additional sequence metal ions in precursor solution. With addition S─Sn─Cu─Zn (STCZ), higher values + /Cu 2+ Sn 4+ /Sn ratios are obtained, surface grain growth modulated...
Ferroptosis, a form of regulated cell death (RCD) that relies on excessive reactive oxygen species (ROS) generation, Fe2+ accumulation, abnormal lipid metabolism and is involved in various organ ischemia/reperfusion (I/R) injury, expecially myocardium. Mitochondria are the powerhouses eukaryotic cells essential regulating multiple RCD. However, links between mitochondria ferroptosis still poorly understood. Salidroside (Sal), natural phenylpropanoid glycoside isolated from Rhodiola rosea,...
Abstract Pyro‐phototronic and piezo‐phototronic effect have shown their important roles for high performance heterojunction‐based photodetectors (PDs). Here, a coupling of pyro‐phototronic is utilized to fabricate self‐powered broadband PD based on the MAPbI 3 single‐crystal film/n‐Si heterojunction. First, by using derived from , maximum photoresponsivity 1.5 mA W −1 780 nm illumination, which enhanced more than 20 times in consideration relative peak‐to‐peak output current. Light‐induced...
The authors have each completed and submitted an ICMJE form for disclosure of potential conflicts interest. declare that they no competing interests, financial or otherwise, related to the current work. All report since initial planning work, this study was funded by Chongqing Natural Science Foundation (Chongqing Technology Development Foundation) (No. CSTB2024NSCQ-KJFZMSX0027).
Breast cancer remains the leading cause of cancer-related deaths among women worldwide, necessitating more effective treatment strategies. Chemotherapy combined with immunotherapy is first-line for breast cancer, but it still suffers from limited therapeutic efficiency and serious side effects, which are usually due to poor delivery efficiency, drug resistance tumor cells, immunosuppressive microenvironment. This study explores development ultrasound-responsive nanobubbles (Ce6/PTX Nbs)...
It has been recognized that iron overload may harm the body's health. Vascular endothelial cells (VECs) are one of main targets injury, and mechanism involved was thought to be related excessive generation reactive oxygen species (ROS). However, subcellular temporal characteristics ROS generation, potential downstream mechanisms, target organelles in VECs injured by have not expounded yet. In this study, we elucidated abovementioned issues through both vivo vitro experiments. Mice were fed...
NLRC5 has been reported to be involved in antiviral immunity; however, the underlying mechanism remains poorly understood. Here, we investigated functional role of infection a flavivirus, dengue virus (DENV). We found that expression was strongly induced by and IFNB or IFNG stimulation different cell lines. Overexpression remarkably suppressed DENV infection, whereas knockout led significant increase infection. Mechanistic study revealed interacted with viral nonstructural protein 3 (NS3)...
Doxorubicin (Dox) with cardiotoxicity and endotheliotoxicity limits its clinical application for cancer. The toxicitic mechanism involves excess ROS generation. 14-3-3s have the protective effects on various injured tissues cells. Tetramethylpyrazine (TMP) is an alkaloid extracted from rhizome of Ligusticum wallichii has multiple bioactivities. We hypothesize that TMP vascular endothelium by upregulating 14-3-3 γ . To test hypothesis, Dox-induced was used to establish injury models in mice...
NaTFSI addition in the precursor solution of CZTSSe improves crystalline quality and defect structure absorption layer film, thereby enhancing efficiency devices.
Identifying people with a high risk of developing diabetes among those prediabetes may facilitate the implementation targeted lifestyle and pharmacological interventions. We aimed to establish machine learning models based on demographic clinical characteristics predict incident diabetes. used data from free medical examination service project for elderly who were 65 years or older develop logistic regression (LR), decision tree (DT), random forest (RF), extreme gradient boosting (XGBoost)...
Abstract Aims This study investigated the efficacy of Limosilactobacillus fermentum-fermented ginseng for improving colitis and gut microbiota profiles in rats explored benefits L. fermentum fermentation process to ginseng. Methods results Ginseng polysaccharide ginsenoside from fermented were analysed by UV HPLC. Antibiotic-fed treated with a fermentum–ginseng mixture. Histopathology- immune-related factors (TNF-α, IL-1β, IL-6 IL-10) colon assayed using pathological sections ELISA. After...
Introduction The prevalence of ischemic heart disease has reached pandemic levels worldwide. Early revascularization is currently the most effective therapy for diseases but paradoxically induces myocardial ischemia/reperfusion (MI/R) injury. Cardiac inflammatory reaction and oxidative stress are primarily involved in pathology MI/R Low-intensity pulsed ultrasound (LIPUS) been demonstrated to reduce cell injury by protecting against many diseases, including cardiovascular rarely on Methods...
Abstract Going beyond the limitations of technology, time, and platform lifecycles, achieving long‐term preservation social media collective memory is an important issue. As a action involving multiple stakeholders, faces complex problem space. Taking China as example, this study revealed, from perspective underlying logic cultural, ethical, legal, other issues that encounters, namely, tension arising differences in stakeholders' interests power inequalities. We specifically investigated...