A5101736313- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Virology and Viral Diseases
- Animal Virus Infections Studies
- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Anorectal Disease Treatments and Outcomes
- T-cell and Retrovirus Studies
- Botulinum Toxin and Related Neurological Disorders
- Minimally Invasive Surgical Techniques
- Cancer Immunotherapy and Biomarkers
- Antibiotic Use and Resistance
- Pancreatic and Hepatic Oncology Research
- Cytokine Signaling Pathways and Interactions
- Viral Infections and Vectors
- Gastrointestinal disorders and treatments
- Pneumonia and Respiratory Infections
- Microbial infections and disease research
- Craniofacial Disorders and Treatments
- Colorectal Cancer Treatments and Studies
- Teratomas and Epidermoid Cysts
- Virus-based gene therapy research
- Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
National Institute of Infectious Diseases
1970-2025
Sasebo City General Hospital
2021-2024
Nagasaki University
2012-2024
Osaka University
2023
Ureshino Medical Center
2022
National Hospital Organization
2022
Kobe Children's Hospital
2021
Nagasaki Medical Center
2016-2018
Nagasaki University Hospital
2017
Jikei University School of Medicine
2010-2011
In locally advanced pancreatic body cancers, cancer infiltrates major vessels such as the celiac axis, common hepatic artery and superior mesenteric or vein, which is borderline of resectability. Patients also suffer severe abdominal pain. Kondo Hirano et al. developed a radical operation called "distal pancreatectomy with en bloc resection (DP-CAR)" for cases. We applied this procedure three times in two patients carcinomas, combined vascular was necessary. Radical eventually achieved.
Scrub typhus, caused by Orientia tsutsugamushi, is a neglected and reemerging disease that causes considerable morbidity mortality. It now extends beyond the Tsutsugamushi Triangle, region wherein it has traditionally been endemic. Influenza also resurged since infection control measures against COVID-19 were relaxed. A few cases of scrub typhus influenza co-infection have reported. Herein, we report case 74-year-old woman with fever upper respiratory symptoms diagnosed treated oseltamivir;...
SUMMARY We have prepared and characterized monoclonal antibodies against five major structural proteins, i.e. the HA, P, NP, F M of measles virus. At least three non-overlapping antigenic sites were delineated on HA protein, four proteins by competitive binding assays. Antigenic roughly represented functional domains defined serological tests. The reactivity with various virus strains including those from subacute sclerosing panencephalitis (SSPE) other members morbillivirus family was...
The purpose of the study was to determine safety and feasibility a 15-day protocol low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with intensive occupational therapy (OT) on motor function spasticity in hemiparetic upper limbs poststroke patients.Fifteen patients (age at entry 55 ± 17years, time after stroke 57± months) limb hemiparesis categorized as Brunnstrom stages 3–5 forhand–fingers were recruited. They considered have reached plateau state entry, based lack...
The course of natural infection with measles virus was examined serologically and histopathologically in monkeys which were kept routine quarantine. Giant cells the Warthin-Finkeldey type consistently detected lymph nodes biopsied one week after estimated time infection, they considered to be caused by infection.Histopathological responses subcutaneous inoculations various strains then compared strict isolation from infection. wild consisting either throat washings patients or infected...
To clarify whether the efficacy of combined low-frequency repetitive transcranial magnetic stimulation (rTMS) and intensive occupational therapy (OT) depends on baseline severity upper limb hemiparesis after stroke.Retrospective comparative study.Department Rehabilitation Medicine at a university hospital.Fifty-two patients who had sustained stroke (age: 57 ± 13 years; time onset: 50 33 months). Based Brunnstrom stage for hand-fingers admission, were divided into Stage 3 group (n = 13), 4...
The aim of this retrospective study was to evaluate the clinical relevance serum p53 antibody (S-p53Ab) as a biomarker and investigate whether its diagnostic value could be improved when combined with other biomarkers gastric cancer (GC).Serum samples were obtained preoperatively from 208 patients histologically-confirmed GC, including 126 stage I (60.6%). Levels S-p53Ab assessed by commercial laboratory using an anti-p53 detection kit. cut-off for 1.3 U/ml.S-p53Ab detected in 16.3% (34 208)...
Suppression of the cellular and humoral immune capacities Japanese quails was attempted by surgical thymectomy on 7th day hatch bursectomy hatch. Degree immunosuppression response evaluated graft-versus-host reaction skin graft rejection, that antibody production to sheep red blood cells virus antigen. In thymectomized significant suppressionn immunity demonstrated, whereas capacity remained almost normal. bursectomized quails, suppression observed without any detectable response. When...
Background: Totally implantable central venous access ports, are required for various purposes, ranging from chemotherapy to nutrition. Port infection is a common complication. In many patients with port infection, the ports removed because antibiotics ineffective. We evaluated risk factors associated removal due infection. Methods: By retrospective chart review, we collected data of 223 who underwent any reason. was defined as symptoms, such fever; elevated white blood cell counts or...
Response of Japanese quails to an inoculation Schmidt-Rup-pin strain Rous sarcoma virus (SR-RSV) was examined. The were as susceptible chick embryo cells the infection SR-RSV. tumors induced in contained a significant amount infectious and avian leukosis group-specific CF antigen at early stages 1 3 weeks after inoculation, but they turned be noninf ective late stage with concomitant disappearance antigen. High incidence regression observed by low dose virus, while high rarely regressed.The...
A male neonate presented with Goldenhar's syndrome (oculoauriculovertebral dysplasia), a combination of facial microsomia and auricular malformation, associated occipital meningoencephalocele. Three-dimensional computed tomography images clearly showed suboccipital cranial cleft extending to the foramen magnum hypogenesis left temporal bone. The patient died heart failure due ventricular septal defect at age 5 months.
The aim of this study was to compare the clinical outcomes laparoscopic versus open surgery for total mesorectal excision (TME) with lateral pelvic lymph node dissection (LPLD) in advanced lower rectal cancer.Forty-four patients who underwent TME LPLD cancer (pStage II/III) between January 2008 and December 2014 were divided into two groups according type surgical approach as follows: group (OLD, n=17) (LLD, n=27).Operative time comparable (p=0.15), whereas intraoperative blood loss...
To compare the clinical and oncological outcomes of laparoscopic open approaches in patients with advanced rectal cancer.In this study, 78 who underwent surgery for middle lower cancer (pStage II - III) were divided into two groups according to type surgical approach: (LS group; n=40) (OS group: n=38). The compared between groups.The operation time was comparable, whereas operative blood loss complication rates significantly less LS group OS group. Cancer-specific survival (CSS) local...
Temperature-dependent growth restriction was studied with the measles vaccine strains licensed in Japan comparison their parental wild strains. Plaquing efficiency compared at various temperatures from 35 to 40 C. AIK-C strain derived Edmonston temperature-sensitive 39 C shutoff temperature. No significant of found for other strains, i.e., Schwarz, FF-8, and CAM-70, Tanabe . A paradoxical feature FF-8 strain; spite undiminished plaquing C, fluid medium markedly depressed or above.
Pelvic exenteration (PE) is a highly invasive procedure with high morbidity and mortality rates. Promising options to reduce this invasiveness have included laparoscopic transperineal approaches. The aim of study was identify the safety combined transabdominal endoscopic PE for colorectal malignancies.Fourteen patients who underwent (T group: 2-team approach, n = 7; O 1-team 7) malignancies between April 2016 March 2020 in our institutions were study. Clinicopathological features...
Extended total mesorectal excision (ETME) is defined as en bloc resection of the adjacent organs outside fascia, that indicated in cases with locally advanced lower rectal cancer (T4 tumor). The aim this study was to evaluate clinical and oncological outcomes laparoscopic ETME (L-ETME) for cancer.The present analyzed 11 consecutive patients who underwent L-ETME cT4 Nagasaki Medical Center between 2012 2015.Of patients, 7 neoadjuvant therapy, pelvic node dissection. One case (7.1%) anterior...
Abstract Background Colorectal cancer (CRC) is the most malignant complication in patients with Crohn’s disease (CD). We report 6 cases of CD-related CRC treated surgically at our hospital. Case presentation From 2010 to 2016, six CD were diagnosed CRC. All < 25 years old, and interval from onset diagnosis was > 10 (range, 15–42 years) all patients. The histological type mucinous carcinoma two cases, well-differentiated tubular adenocarcinoma moderately differentiated cases. detected...
Purpose The incidence of anastomotic leakage (AL) associated with sphincter-preserving surgery has increased. Diverting stoma (DS) and transanal tube (TT) placement have been reported to reduce the rate AL. This multicenter study examined efficacy TT DS for preventing AL in rectal cancer patients. Methods We reviewed 126 patients who underwent low anterior resection double-stapling reconstruction between April 2016 March 2020. Patients were divided into 2 groups according presence (n = 90)...