A5101561513- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- COVID-19 and healthcare impacts
- Lung Cancer Research Studies
- COVID-19 Clinical Research Studies
- Lung Cancer Treatments and Mutations
- Economic and Financial Impacts of Cancer
- Advanced Nanomaterials in Catalysis
- Palliative Care and End-of-Life Issues
- Lung Cancer Diagnosis and Treatment
- Nanoparticle-Based Drug Delivery
- Cancer Immunotherapy and Biomarkers
- Cardiac tumors and thrombi
- Immune cells in cancer
- Nanoplatforms for cancer theranostics
- Neutropenia and Cancer Infections
- Cancer survivorship and care
- Viral Infectious Diseases and Gene Expression in Insects
- Effects of Radiation Exposure
- Radiation Therapy and Dosimetry
- Aquatic Ecosystems and Phytoplankton Dynamics
- Vascular Tumors and Angiosarcomas
- Epigenetics and DNA Methylation
Huazhong University of Science and Technology
2018-2025
Union Hospital
2018-2025
Union Hospital
2024
Shandong University
2023
Tianjin Beichen Hospital
2023
Wuhan Union Hospital
2020
Abstract Purpose: This study aimed to assess the antitumor activity and safety of neoadjuvant chemotherapy combined with PD-1 inhibitor camrelizumab in patients locally advanced head neck squamous cell carcinoma (HNSCC). Patients Methods: In this single-center, single-arm, phase 2 trial, resectable stage III–IVB HNSCC received [albumin-bound paclitaxel 260 mg/m2 (or docetaxel 75 mg/m2) plus cisplatin mg/m2] 200 mg on day 1 each 21-day cycle for three cycles, followed by surgery, adjuvant...
Radioresistance is the major factor of glioblastoma multiforme (GBM) treatment failure and relapse. Hypoxia autophagy are linked to radioresistance poor prognosis in solid tumors, but mechanisms remain unknown. Thus, we hypothesize that hypoxia may activate through two critical factors, HIF1A Beclin-1, resulting GBM vitro vivo. In this study, first demonstrated was overexpressed tissues predicted a via bioinformatics. Secondly, determined induced high expression upregulated levels Beclin-1...
To the Editor: Regrettably, oncological discourse has historically sidelined fertility considerations. Patient–practitioner dialogs rarely traverse domain of conservation, a situation worsened by general lack specialized knowledge among healthcare providers. Research endeavors in field radiation and oncofertility are nascent, with detailed explanation on doses for different tissues insufficient elaboration reproductive physio-endocrinology, leaving vast territories uncharted. Therefore, it...
The COVID-19 pandemic is a significant worldwide health crisis. Breast cancer patients with are fragile and require particular clinical care. This study aimed to identify the characteristics of breast risks associated anti-cancer treatment.The medical records laboratory-confirmed were collected among 9559 from seven designated hospitals 13th January 18th March 2020 in Hubei, China. Univariate multivariate analyses performed assess risk factors for severity.Of 45 COVID-19, 33 (73.3%)...
To systematically explore the genes mediating functional crosstalk between metazoan biological processes, we apply comparative genetic interaction (GI) mapping in Saccharomyces cerevisiae and Caenorhabditis elegans to generate an inter-bioprocess network consisting of 178 C. GIs. The GI spans six annotated processes including aging, intracellular transport, microtubule-based cytokinesis, lipid metabolic anatomical structure development. By proposing a strategy called "reciprocal test" for...
Supplementary Data from Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
Supplementary Data from Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
Supplementary Data from Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
<div>AbstractPurpose:<p>This study aimed to assess the antitumor activity and safety of neoadjuvant chemotherapy combined with PD-1 inhibitor camrelizumab in patients locally advanced head neck squamous cell carcinoma (HNSCC).</p>Patients Methods:<p>In this single-center, single-arm, phase 2 trial, resectable stage III–IVB HNSCC received [albumin-bound paclitaxel 260 mg/m<sup>2</sup> (or docetaxel 75 mg/m<sup>2</sup>) plus cisplatin...
Supplementary Data from Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
Supplementary Data from Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial