A5016154594- Heavy Metal Exposure and Toxicity
- Animal Virus Infections Studies
- Trace Elements in Health
- Arsenic contamination and mitigation
- Virus-based gene therapy research
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Effects and risks of endocrine disrupting chemicals
- Heavy metals in environment
- Selenium in Biological Systems
- Air Quality and Health Impacts
- Viral gastroenteritis research and epidemiology
- Environmental and Agricultural Sciences
- Pharmacological Effects of Natural Compounds
- Pesticide and Herbicide Environmental Studies
- Gestational Diabetes Research and Management
- Soil and Water Nutrient Dynamics
- Electrochemical Analysis and Applications
- Advancements in Transdermal Drug Delivery
- Ideological and Political Education
- Birth, Development, and Health
- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Education and Work Dynamics
- Toxic Organic Pollutants Impact
Northwest A&F University
2013-2025
Center for Excellence in Molecular Cell Science
2025
University of Chinese Academy of Sciences
2025
Wuchang University of Technology
2022-2025
Wuhan Polytechnic University
2015-2024
South China Agricultural University
2013-2024
Yunnan Academy of Agricultural Sciences
2024
Tea Research Institute
2024
Shenyang University
2010-2024
Jilin Agricultural Science and Technology University
2024
There is limited evidence on the effects of arsenic species and metabolic capacity child neurodevelopment, particularly at low levels. Further, little known about critical window exposure. To estimate associations exposure metabolism in different pregnancy periods with neurodevelopment two-year-old children. Concentrations arsenobetaine (AsB), arsenite, arsenate, monomethyl acid (MMA), dimethyl (DMA) urine samples collected three trimesters from 1006 mothers were measured using HPLC − ICPMS....
Abstract Invasive pulmonary aspergillosis (IPA) is a life‐threatening complication in patients with severe fever thrombocytopenia syndrome (SFTS), yet SFTS‐associated IPA (SAPA)'s risk factors remain undefined. A multicenter retrospective cohort study across Hubei and Anhui provinces (May 2013–September 2022) utilized least absolute s hrinkage selection operator (LASSO) regression for variable selection. Multivariable logistic identified independent predictors of SAPA, Cox highlighted...
We previously demonstrated that baicalin had efficacy against gouty arthritis (GA) by oral administration. In this paper, a novel baicalin-loaded microemulsion-based gel (B-MEG) was prepared and assessed for the transdermal delivery of GA. The preparation method capability B-MEG screened optimized using central composite design, Franz diffusion cell experiments, split-split plot design. Skin irritation tests were performed in guinea pigs. anti-gout effects evaluated mice. comprised 50 % pH...
Porcine epidemic diarrhea virus (PEDV) causes a porcine disease associated with swine diarrhea. The type I interferon (IFN-I or IFN α/β) is key mediator of innate antiviral response during infection. Different antagonistic strategies have been identified and determined as to how PEDV infection inhibits the host’s responses escape host immune pathway, but pathogenic mechanisms are not fully elucidated. Our preliminary results revealed that endogenous TANK-binding kinase 1 (TBK1) regulatory...
Importance Although the effects of lead (Pb) exposure on neurocognition in children have been confirmed, individual associations prenatal Pb and its interaction with genetic factors cognitive developmental delay (CDD) remain unclear. Objective To investigate association CDD risk. Design, Setting, Participants Women Wuhan, China, who had an expected delivery date between March 2014 December 2017, were recruited for this prospective cohort study. Children assessed development at approximately...
Abstract Genomic imprinting is required for sexual reproduction and embryonic development of mammals, in which, differentially methylated regions (DMRs) regulate the parent-specific monoallelic expression imprinted genes. Numerous studies on genes have highlighted their critical roles development. However, what network essential still unclear. Here, we establish a stepwise system to reconstruct development-related network, which diploid stem cells (ESCs) are derived by fusing between...
SUMMARY DREB1A, a pivotal transcription factor, has long been known to regulate plant abiotic stress tolerance. However, its role in biotic tolerance and the underlying mechanisms have remained mystery. Our research reveals that maize ZmDREB1A gene is up‐regulated seedlings when plants are infected by Rhizoctonia solani ( R. ). The knock‐out mutant exhibits increased disease resistance against pathogen . Further investigation showed regulates salicylic acid (SA) metabolism inhibiting ZmSARD1...
The authors examined the development of diabetic retinopathy in a population-based cohort persons with incident type 1 diabetes to investigate possibility lowered prevalence and severity compared previous US studies. A total 474 from Wisconsin were followed diagnosis through 4–14 years' duration during 1990–2002. Retinopathy was determined by fundus photography at 4, 7, 9, 14 duration. Risk developing modeled on demographic diabetes-care characteristics means generalized linear model using...
Prenatal exposure to chromium may be associated with reduced birth weight; however, critical windows of such for fetal growth are unclear. Our study was aimed assess trimester-specific associations parameters measured repeatedly by ultrasound and size, see whether these were modified sex. We conducted a prospective cohort 3041 women in Wuhan, China, from 2013 2016. Chromium concentrations maternal urine samples collected the 1st, 2nd, 3rd trimesters using an inductively coupled plasma mass...
Porcine parvovirus (PPV) infection primarily causes reproductive failure of pregnant swine and results in host cell death. Boars, as an important disseminator, shed PPV to sows via semen. infects numerously replicates boar testicle, which damage testicle vivo. Reactive oxygen species (ROS), a mediator apoptosis, play crucial role the mitochondria apoptotic pathway. However, whether induces ST cells apoptosis ROS accumulation is still unclear. To determine effects on we detected morphological...