Nikolaos Makris

ORCID: 0000-0001-9858-6940
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About
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Research Areas
  • Gynecological conditions and treatments
  • Multiple Myeloma Research and Treatments
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Cardiac Imaging and Diagnostics
  • Peptidase Inhibition and Analysis
  • Cardiovascular Disease and Adiposity
  • Protease and Inhibitor Mechanisms
  • Neuroendocrine regulation and behavior
  • Acute Myocardial Infarction Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Reproductive System and Pregnancy
  • Protein Degradation and Inhibitors
  • Cardiovascular Health and Disease Prevention
  • Cancer Treatment and Pharmacology
  • Ovarian cancer diagnosis and treatment
  • Apelin-related biomedical research
  • Clinical practice guidelines implementation
  • Prenatal Screening and Diagnostics
  • Menstrual Health and Disorders
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Maternal and fetal healthcare
  • Neuroscience of respiration and sleep

National and Kapodistrian University of Athens
2007-2023

Klinikum Stuttgart
2023

Rudolfinerhaus Hospital
2022

Alexandra Hospital
1999-2021

Harvard University
2017

Essen University Hospital
2013

Athens State University
2012

Novem (Netherlands)
2011

Athens Eye Hospital
2011

Sotiria General Hospital
2011

10.1016/j.mpaic.2023.11.014 article EN Anaesthesia & intensive care medicine 2024-02-17

Abstract Aim: To evaluate the role of Gynecare (Ethicon, Somerville, NJ, USA) bipolar resectoscope in resecting fibroids, and effect hysteroscopic myomectomy on infertility pregnancy outcomes. Methods: From January 2000 to December 2005, we studied 59 women reproductive age with menorrhagia, submucous myomas one or more factors. All who participated had been subfertile for over 2 years. Fifteen displayed myoma type O (intracavitary), 34 I (less than 50% within myometrium) remaining 10 II...

10.1111/j.1447-0756.2007.00667.x article EN Journal of Obstetrics and Gynaecology Research 2007-11-12

Men with Down syndrome are considered as infertile although the causes of infertility not known in detail yet. Although this constitutes a general rule there three confirmed cases parenting by fathers syndrome. Many investigators have addressed and their studies indicate that may be hormonal deficits, morphological alterations gonads, abnormal spermatogenesis, psychological social factors related to mental retardation. It is obvious extra chromosome 21 has detrimental direct indirect effect...

10.1111/j.1439-0272.2010.01043.x article EN Andrologia 2011-08-02

Abstract Objective: Associations of endogenous androgens in menopause with blood pressure (BP) and indices arterial stiffness are reported, but directional relationships not clear. Structural equation modeling is a contemporary statistical method, which allows assessment such improves pathway understanding. Methods: We recruited 411 consecutive apparently healthy postmenopausal women who underwent noninvasive vascular evaluation. This included pulse wave analysis (aortic pressures...

10.1097/gme.0000000000000822 article EN Menopause The Journal of The North American Menopause Society 2017-02-14

Ubiquitin-Proteasome System (UPS) is of paramount importance regarding the function myocardial cell. Consistently, inhibition this system has been found to affect myocardium in experimental models; yet, clinical impact UPS on cardiac not comprehensively examined. Our aim was gain insight into effect proteasome mechanics humans.We prospectively evaluated 48 patients with multiple myeloma and an indication receive carfilzomib, irreversible inhibitor. All were initially underwent...

10.1093/ehjci/jeac168 article EN European Heart Journal - Cardiovascular Imaging 2022-08-18

Abstract Aims Complete haematologic response to treatment for light chain cardiac amyloidosis (AL-CA) may lead improvement of myocardial function and better outcomes. We sought evaluate the effect AL-CA on echocardiographic indices deformation work their prognostic significance. Methods results Sixty-one patients treated AL were enrolled underwent assessment at baseline 1 year. Patients stratified according as complete or not responders. A significant reduction in median N-terminal pro-brain...

10.1093/ehjci/jead351 article EN European Heart Journal - Cardiovascular Imaging 2023-12-24

Merkel cell carcinoma (MCC) is a rare potentially fatal skin tumor affecting older and immunosuppressed individuals. It highly malignant with high rates of metastasis poor survival. We present case 67-year-old woman palpable mass in the upper abdomen. An abdominal CT revealed tail pancreas. Two weeks before, lumpectomy 3.5 cm left breast had been performed. Histology showed primary neuroendocrine mammary gland. The patient's medical history was significant for 0.7 × 0.9 MCC removed from her...

10.1186/1477-7819-11-261 article EN cc-by World Journal of Surgical Oncology 2013-01-01

Abstract: The oxytocin (OT)‐oxytocin receptor (OTR) system of the mammalian uterus has mainly been studied in relation to its involvement onset labor. aim this study was elucidate vivo expression and localization pattern OTR mouse endometrium embryo during implantation, as well mRNA vitro developing embryo. or OT detected immunohistochemically uterine tissue sections 5‐ 8‐week‐old female mice between days 4 10 an established pregnancy. In addition, by means reverse transcription polymerase...

10.1196/annals.1365.046 article EN Annals of the New York Academy of Sciences 2006-12-01

We describe the case of a 54-year-old white man who experienced bilateral central serous chorioretinopathy following laser in situ keratomileusis for myopia. Postoperatively, uncorrected visual acuity was 20/20 both eyes. One month later, patient reported decrease vision Dilated fundus examination, fluorescein and indocyanine green angiography, optical coherence tomography showed chorioretinopathy. Photodynamic therapy performed twice, improved. Financial Disclosure: No author has financial...

10.1016/j.jcrs.2011.01.017 article EN Journal of Cataract & Refractive Surgery 2011-04-01

Carfilzomib has improved survival in patients with relapsed/refractory multiple myeloma (RRMM), but it may exert cardiovascular adverse events (CVAEs). The aim of this study was to assess whether treatment daratumumab ameliorate carfilzomib-related toxicity. We prospectively evaluated 25 RRMM who received either combination carfilzomib and dexamethasone (DaraKd) (n = 14) or Kd 11). Cardiac ultrasound performed before initiation C6D16 at the time interruption. Patients were followed for a...

10.3390/cancers13205057 article EN Cancers 2021-10-09

The purpose of this study was to evaluate the efficacy and safety local cervical application mepivacaine hydrochloride for reducing pain associated with hysteroscopy. Among patients who underwent hysteroscopic evaluation over a 6-year period (1994-1999) at hysteroscopy unit First Department Obstetrics Gynecology University Athens, in 245 anesthesia necessary. In 45 patients, general decided on, various reasons. remaining 200 were randomized into two groups 100. Patients group given by...

10.1089/104240601750200332 article EN Journal of Gynecologic Surgery 2001-03-01

The purpose of this study was to assess the relationship mammographic breast density (BD) and cell proliferation/focal adhesion kinase activation-seeking radiotracer technetium 99m pentavalent dimercaptosuccinic acid (99mTc(V)-DMSA) uptake in women with different histologies, that is, mild epithelial hyperplasia (MEH), florid (FEH), mixed ductal carcinoma situ invasive (DCIS + IDC), pure IDC. Fifty-five histologically confirmed mammary pathologies were submitted preoperatively mammography...

10.2310/7290.2010.00056 article EN cc-by-nc Molecular Imaging 2011-09-01

Key Clinical Message Electrocardiographic (ECG) changes occurring several hours after the onset of acute cardiogenic pulmonary edema have been seldom described. The proposed explanatory mechanisms are various and not fairly established. In absence significant coronary artery disease, these ECG abnormalities could be attributed to implicated in microcirculatory dysfunction.

10.1002/ccr3.1899 article EN cc-by Clinical Case Reports 2018-11-12

AbstractThe aim of this study was to investigate the effect human hydrosalpinx fluid (HF) on development and blastulation mouse embryos role concentration growth factors in culture medium with without HF. In total, 2100 were cultured. Female mice induced superovulate then mated males. Two-cell-stage recovered from oviduct cultured Ham's F-10 bovine serum albumin Epidermal factor (EGF) insulin-like factor-I (IGF-I) analyzed by quantitative enzyme immunoassay. Mean index 1.11, 0.97 0.98 found...

10.1080/09513590400020872 article EN Gynecological Endocrinology 2005-01-01

Zusammenfassung Das primär kutane periphere T-Zell-Lymphom, nicht weiter spezifiziert (pcPTCL-NOS), ist eine seltene, zügig fortschreitende, maligne Erkrankung, die sich in schnell wachsenden Plaques oder Knoten manifestiert. Hier berichten wir über den Fall einer 42-jährigen Patientin, bei der nach histologischem Nachweis des pcPTCL-NOS trotz relativ niedriger prozentualer Expression von CD30-Antigen ein erfolgreicher therapeutischer Einsatz Brentuximab Vedotin erfolgte. Nach 6 Wochen gab...

10.1055/a-2013-5798 article DE Aktuelle Dermatologie 2023-06-01
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