Yitan Chen

ORCID: 0000-0001-9868-3097
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About
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Research Areas
  • MicroRNA in disease regulation
  • Mental Health Research Topics
  • Psychometric Methodologies and Testing
  • Behavioral Health and Interventions
  • Microbial infections and disease research
  • Immune cells in cancer
  • Dermatologic Treatments and Research
  • Pneumonia and Respiratory Infections
  • Mechanisms of cancer metastasis
  • Intracranial Aneurysms: Treatment and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Meningioma and schwannoma management
  • Facial Nerve Paralysis Treatment and Research
  • Chemokine receptors and signaling
  • Trigeminal Neuralgia and Treatments
  • Epigenetics and DNA Methylation
  • Cancer-related molecular mechanisms research
  • Cerebrovascular and Carotid Artery Diseases
  • Protein Kinase Regulation and GTPase Signaling
  • Optical Coherence Tomography Applications
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • RNA modifications and cancer
  • Circular RNAs in diseases
  • Blood groups and transfusion

Washington University in St. Louis
2022-2024

Boston College
2022

University of Macau
2021

Chinese People 's Liberation Army No. 85 Hospital
2016

Air Force Medical University
2012

Xijing Hospital
2012

82th Hospital of Pla
2012

Abstract Hindlimb ischemia is a major complication of diabetic patients due to poor neovascularization. Therapy with pulsed electromagnetic fields (PEMF) can promote angiogenesis in ischemic lesions. However, the efficacy and therapeutic mechanisms PEMF diabetes‐related hindlimb are unclear. Sprague–Dawley rats were injected streptozocin induce diabetes, 10 weeks later subjected surgical induction acute ischemia. The randomized treated PEMF, blood perfusion individual was determined...

10.1002/bem.21755 article EN Bioelectromagnetics 2012-09-05

As one of the leading cause cancer-related deaths in worldwide, lung cancer needs to be understood better. Nowadays, increasing point mutations specific oncogenes are biomarkers used predict therapeutic effect targeted therapy and has entered age individual treatment. At present, many relevant researchers have suggested that EGFR is a biomarker therapy. A large number evidence indicates EGFR/Akt pathway plays important role growth metastasis.In this paper, we found was target...

10.1080/01902148.2016.1207726 article EN Experimental Lung Research 2016-07-02

The incidence of lung cancer in China increases annually, and effective targets for the diagnosis treatment are urgently needed. miRNAs currently considered to be involved regulation tumor development growth. miR‑24 has been found contribute several tumors. Menin is a key suppressor gene, its expression generally low cancer. effects on biological behavior cells were detected by MTT Transwell assays. In present study, was associated with menin, affecting activity SMAD3 pathway inhibiting...

10.3892/or.2018.6327 article EN cc-by Oncology Reports 2018-03-20

Glucocorticoids are the most common cause of secondary osteoporosis, which affects both women (pre- and postmenopausal) men. In cases prolonged treatment, glucocorticoids promote loss inactivation differentiational function bone marrow mesenchymal stromal cells (BMSCs), risking development skeletal system diseases such as osteoporosis. This study reports for first time protective effect antimalarial artemisinin against glucocorticoid-induced insults on primary cultured rat BMSCs. At...

10.1155/2021/5574932 article EN cc-by Oxidative Medicine and Cellular Longevity 2021-01-01

The presence-severity response format uses a filter question to ask about the presence of symptom, followed by severity that symptom. Only an affirmative triggers follow-up question. Despite its widespread use, little research has compared psychometric properties those traditional single-item format. purpose this was understand how questions influence item responses and characteristics on several short health-related questionnaires. Using two different experimental designs, we find depending...

10.31234/osf.io/bxj7f preprint EN 2022-06-30

The presence-severity response format uses a filter question to ask about the presence of symptom, followed by severity that symptom. Only an affirmative triggers follow-up question. Despite its widespread use, little research has compared psychometric properties those traditional single-item format. purpose this was understand how questions influence item responses and characteristics on several short health-related questionnaires. Using two different experimental designs, we find depending...

10.1177/10731911221133310 article EN Assessment 2022-11-05

Objective To investigate the effect of modified method skull closing in microvascular decompression (MVD) on incidence postoperative cerebrospinal fluid (CSF) leakage. Methods We retrospectively analyzed clinical data 257 patients who underwent MVD from August 2013 to October 2016 at Department Neurosurgery, Affiliated Hospital Southwest Medical University. Among them, traditional was used 151 cases before July 2015 and 106 received after 2015. The modifications involved aspects...

10.3760/cma.j.issn.1001-2346.2017.09.011 article EN Zhonghua shenjing waike zazhi 2017-09-28

Objective To explore the effect of microvascular decompression (MVD) on blood pressure in treatment hypertensive patients with cerebral nerve disorders and value preoperative MRI examination for operation. Methods From January 2015 to October 2016, 72 were admitted Department Neurosurgery, Affiliated Hospital Southwest Medical University enrolled into this retrospective study. We evaluated relationship between vessels rostral ventrolateral medulla (RVLM) surgical side before operation...

10.3760/cma.j.issn.1001-2346.2018.09.014 article EN Zhonghua shenjing waike zazhi 2018-09-28
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