- Meat and Animal Product Quality
- Animal Nutrition and Physiology
- Gut microbiota and health
- Muscle Physiology and Disorders
- Adipose Tissue and Metabolism
- Proteins in Food Systems
- Edible Oils Quality and Analysis
- Probiotics and Fermented Foods
- Metabolomics and Mass Spectrometry Studies
- Cholesterol and Lipid Metabolism
- Functional Brain Connectivity Studies
- Food Chemistry and Fat Analysis
- Autism Spectrum Disorder Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Antibiotics Pharmacokinetics and Efficacy
- Biochemical effects in animals
- Trace Elements in Health
- Ginseng Biological Effects and Applications
- Venous Thromboembolism Diagnosis and Management
- Analytical Chemistry and Chromatography
- Health and Wellbeing Research
- Rabbits: Nutrition, Reproduction, Health
- Microencapsulation and Drying Processes
- Axon Guidance and Neuronal Signaling
Second Hospital of Anhui Medical University
2025
Anhui Medical University
2025
China Agricultural University
2018-2024
Harbin University of Commerce
2022-2024
Guizhou University
2023-2024
China National Center for Biotechnology Development
2023
Peking University
2018-2022
Peking University Sixth Hospital
2018-2022
Hangzhou Normal University
2021
Jinan Central Hospital
2010-2018
Chinese indigenous chicken breeds are widely used as food in China but their slow growth rate and long farming cycle has limited industrial production. In the current study we examined whether market weights of native were related to specific cecal bacteria, serum metabolites inflammatory cytokines. We bacterial taxa using 16S rDNA analysis along with untargeted found that microbiota could explain 10.1% individual differences identified key genera influenced this phenotype. The presence...
Previous studies have shown a positive association between sedentary behavior (SB) and metabolic syndrome (MetS), but no assessed the mediating effect of depressive symptoms in this process. Participants from 2007-2018 National Health Nutrition Examination Survey (NHANES) were included. Multiple logistic regression analyses restricted cubic splines (RCSs) adopted to assess correlations among SB duration, depressed mood MetS. A mediation model was constructed analyze whether there on...
This study is aimed at exploring the mechanism underlying homeostasis between myogenesis and adipogenesis in skeletal muscle using a special porcine model with distinct phenotype on growth rate intramuscular fat deposition. Differentiation potential of muscle-derived Myo-lineage cells lean-type pigs was significantly enhanced relative to obese-type pigs, while that their Adi-lineage similar. Single-cell RNA sequencing revealed reserved higher proportion pigs. Besides, pig settled closer...
Bisphenol A (BPA) is toxic to the reproductive and nervous system, even carcinogenetic in humans animals. However, few studies focused on effects of BPA intestinal tract. Here, we detected BPA-induced injuries mucosa explored a reliable approach counteract effects. C57BL/6J mice were gavage or accompanied with ingestion 4% (w/w) glutamine for 4-wks. In vitro, IEC-6 cells treated 0.4 mmol/L 6 hours mimicking acute injury 0.2 12 followed without inclusion 4 determine cell renewal,...
The balance of adipogenic and myogenic differentiation skeletal muscle-derived mesenchymal stem cells is particularly important in muscle development intramuscular fat deposition. This study aimed to explore the differential regulation between precursors by comparative analysis their global proteome expression profile. Adipogenic isolated from neonatal porcine longissimus dorsi preplate method were verified for unique distinct potential under or induction. A total 433 differentially...
The balance of myogenic and adipogenic differentiation is crucial for skeletal muscle homeostasis. Given the vital role membrane proteins (MBPs) in cell signal perception, proteomics was conducted to delineate mechanisms regulating precursors muscle. Adipogenic with divergent potential were isolated from longissimus dorsi neonatal pigs by preplate method. A total 85 differentially expressed MBPs (P < 0.05 fold change ≥ 1.2 or ≤0.83) between 2 detected via isobaric tags relative absolute...
Abstract Angiotensin II (Ang II) plays a critical role in hypertrophy of cardiomyocytes; however, the molecular mechanism, especially signaling cascades, cardiomyocytes remains unclear. In present study, we examined mechanism Ang cardiomyocytes. rapidly stimulated phosphorylation protein kinase C epsilon (PKCε) time‐ and dose‐dependent manner via receptor‐1 (AT 1 ). Furthermore, II‐induced extracellular signal‐regulated 5 (ERK5) translocation was mediated through signal pathway that involves...
Abstract Background Skeletal muscle is a complex and heterogeneous tissue accounting for approximately 40% of body weight. Excessive ectopic lipid accumulation in the fascicle would undermine integrity skeletal humans but endow with marbling-related characteristics farm animals. Therefore, balance myogenesis adipogenesis great significance homeostasis. Significant DNA methylation occurs during adipogenesis; however, pattern myogenic adipogenic precursors derived from remains unknown yet....
The influence of the fatty acid composition fried oil on oil-absorbing capacity tofu puffs was examined. Two edible vegetable oils and three blends different oleic linoleic ratios were analyzed before after frying, along with rheological properties, composition, value, peroxide p-anisidine value. As well as moisture content, microstructure changes puffs, evaluated. results revealed that viscosity all increased short-time thermal exposure, while value also increased. blend oil, an ratio 1:1,...
The study was conducted to evaluate effects of short-term or long-term administration 25- hydroxyvitamin D3 [25(OH)VD3] on growth performance, bone characteristics, meat quality in growing pigs. A total 144 pigs were allocated into three groups and fed diet contained 2000 IU vitamin (VD3) 25(OH)VD3 for a administration. results showed that increased BW d 56 average daily gain 28–56. Furthermore, feeding calcium content mRNA expressions ion channel protein anti-oxidases genes the liver. In...
This study was conducted to evaluate the effects of activated charcoal-herb extractum complex (CHC) on growth performance, immunological indices, intestinal morphology and microflora in weaning piglets determine optimal supplemental dose. A total 216 weaned (Duroc × Landrace Large White) with an initial body weight 8.55 ± 1.18 kg were randomly assigned six treatment groups; each group had pens, pigs per pen. The period 28 d. Pigs fed a corn-soybean meal-based diet supplemented 500, 1000,...
Autism spectrum disorder is characterized by atypical developmental changes during brain maturation, but regional functional that occur with age and across different frequency bands are unknown. Therefore, the current study aimed to explore potential band-related in activities autism.
Protein restriction (PR) is beneficial for relieving metabolic disorders and aging-related diseases. However, extreme PR could result in malnutrition due to severe deficiency of essential amino acids. Therefore, the effect moderate on insulin sensitivity investigated.
This study was aimed at evaluating the effects of activated charcoal-herb extractum complex (CHC) on antioxidant status, serum lipid metabolites and its safety supplement in weaning piglets. In experiment 1, a total 216 piglets (Duroc × Landrace Large White) weaned 28 days age with initial body weight 8.55 ± 1.18 kg were assigned randomly to six treatment groups. each group had pens, pigs per pen. Pigs fed corn-soybean meal-based diet supplemented 500, 1000, 1500 or 2000 mg kg−1 CHC over two...
Late-life depression (LLD), characterized by cognitive deficits, is considered heterogeneous across individuals. Previous studies have identified subtypes with diverse symptom profiles, but their patterns are unknown. This study aimed to investigate the of LLD and profile each group. In total, 109 depressed older adults were enrolled. We performed latent class analysis using Geriatric Depression Scale items as indicators generate classes. compared sociodemographic clinical characteristics...
The gut microbiome plays a key role in the formation of livestock and poultry traits via serum metabolites, empirical evidence has indicated these are sex-linked.