A5103072415- Gallbladder and Bile Duct Disorders
- Ultrasound in Clinical Applications
- Pancreatitis Pathology and Treatment
- SARS-CoV-2 and COVID-19 Research
- Liver Disease Diagnosis and Treatment
- Birth, Development, and Health
- Cerebrovascular and Carotid Artery Diseases
- Radiology practices and education
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Cardiovascular and Diving-Related Complications
- Cardiovascular Health and Disease Prevention
- Cardiac Valve Diseases and Treatments
- Electrolyte and hormonal disorders
- Intensive Care Unit Cognitive Disorders
- Tryptophan and brain disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Connective tissue disorders research
- Sarcoma Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Tumors and Oncological Cases
- Frailty in Older Adults
- Musculoskeletal synovial abnormalities and treatments
Institute of Laboratory Animal Science
2015-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Mianyang Central Hospital
2024-2025
University of Electronic Science and Technology of China
2024-2025
Sir Run Run Shaw Hospital
2024
Zhejiang University
2024
Karamay Central Hospital
2017-2024
Jinshan Hospital of Fudan University
2023-2024
Academy of Medical Sciences
2020
Union Hospital
2017
Abstract Background Human infections with zoonotic coronaviruses (CoVs), including severe acute respiratory syndrome (SARS)-CoV and Middle East (MERS)-CoV, have raised great public health concern globally. Here, we report a novel bat-origin CoV causing fatal pneumonia in humans. Methods We collected clinical data bronchoalveolar lavage (BAL) specimens from five patients Wuhan Jinyintan Hospital, Hubei province, China. Nucleic acids of the BAL were extracted subjected to next-generation...
The triglyceride-glucose (TyG) index is a novel marker of insulin resistance that has been strongly associated with many diseases related to metabolic disorders, such as diabetes, coronary heart disease, myocardial infarction, obesity, nonalcoholic fatty liver and stroke. However, whether the TyG prevalence gallstones not determined. Therefore, purpose this study was evaluate relationship between in American adults, well age at which adults America undergo their first gallstone surgery. We...
Abstract The global spread of Severe Acute Respiratory Syndrome Coronavirus 2. (SARS-CoV-2) and its variant strains, including Alpha, Beta, Gamma, Delta, now Omicron, pose a significant challenge. With the constant evolution virus, Omicron subtypes BA.1, BA.2, BA.3, BA.4, BA.5 have developed capacity to evade neutralization induced by previous vaccination or infection. This evasion highlights urgency in discovering new monoclonal antibodies (mAbs) with neutralizing activity, especially...
We investigated the association between serum uric acid (SUA) levels and gallstone (GS) prevalence in adult women. Participants' information were taken from United States National Health Nutrition Examination Survey (2017-2020). Logistic regression analysis dose-response curve used to assess SUA of GS Subgroup analyses performed investigate associations age, ethnicity, body mass index, hypertension, diabetes. A total 600 participants self-reported a history GS. After adjusting for...
Gallstones (GS) are closely associated with obesity. The body mass index (BMI) is the most commonly used for evaluating However, BMI does not consider distribution of adipose tissue and differentiate between differences in fat by sex; therefore, only provides a rough indication overweight status. Relative (RFM) an emerging, simple, low-cost anthropometric that reflects obesity (particularly abdominal obesity), various obesity-related diseases. relationship RFM GS has yet been explored....
Lack or downregulation of the dopamine D2 receptor (D2R) results in increased renal expression injury markers and proinflammatory factors that is independent a blood pressure increase. This study aimed to determine mechanisms involved regulation inflammation by D2Rs. Silencing D2Rs mouse proximal tubule cells TNF-α, monocyte chemoattractant protein-1 (MCP-1), IL-6. D2R also Akt phosphorylation activity, glycogen synthase kinase-3β (GSK3β) cyclin D1 expression, downstream targets Akt;...
Background The aim of this study is to evaluate the association between triglyceride glucose-waist height ratio (TyG-WHtR) index and prevalence gallstone disease (GSD), alongside age at first surgery among adult populations within United States. Methods We screened participants using National Health Nutrition Examination Survey (NHANES). Logistic regression analysis, generalized additive modeling, smoothed curve fitting, subgroup analysis were employed assess TyG-WHtR index, GSD, initial...
Rural general practitioners (GPs) have insufficient diagnostic information to deal with complex clinical scenarios due the inequality in medical imaging resources rural and remote communities. The objective of this study is explore value a tele-mentored handheld ultrasound (tele-HHUS) system, allowing GPs provide (US) services communities.Overall, 708 patients underwent tele-HHUS examination between March October 2021 April 2022 across thirteen primary hospitals two tertiary-care hospitals....
The neutrophil percentage to albumin ratio (NPAR) is an emerging, costimulatory indicator of inflammation that associated with a variety diseases, such as non-alcoholic fatty liver disease, fibrosis, stroke, and cardiovascular disease. However, the relationship between NPAR gallstones (GS) has not yet been explored. Therefore, this study aimed evaluate association odds GS age patients at time their first surgery. Participants were selected from National Health Nutrition Examination Survey...
Objectives To examine the repeatability of quantitative time‐intensity curve analysis neovascularization within carotid plaques with contrast‐enhanced ultrasonography (US) and to investigate plaque in patients coronary heart disease using US correlation between risk factors acute syndrome (ACS). Methods Sixty ACS 60 stable artery (CAD) underwent conventional US, enhancement was observed analyzed quantitatively. Carotid performed 1 month occurrence. Interobserver intraobserver variability...
This prospective study explored the value of synchronous tele-ultrasound (US) to aid doctors inexperienced in US with breast examinations. In total, 99 patients were enrolled. Two trainee who (trainee A [TA] and B [TB]) one doctor was an expert completed examinations sequentially. TA independently, while TB instructed by using tele-US. Subsequently, performed on-site person. Separately, they selected most clinically significant nodule as target nodule. Consistency image quality compared...
ABSTRACT Aims and Objectives To explore the relationship between Geriatric Nutritional Risk Index (GNRI) occurrence of Pressure injury (PI) in elderly Intensive Care Unit (ICU) patients. Background PI represent a significant health concern within ICU, where such injuries is notably high among critically ill However, few studies have explored GNRI PI. Design A longitudinal, single‐centre, retrospective study. Methods The study utilised calculation to identify occurrences. comprehensive set...
Purpose Acute fatty liver of pregnancy (AFLP) is a severe complication that can occur in the third trimester or immediately postpartum, characterized by rapid hepatic failure. This study aims to explore changes portal vein blood flow velocity and function during pregnancy, which may assist early diagnosis management AFLP. Methods longitudinal was conducted at tertiary healthcare center with participants recruited from routine antenatal check-ups. The included healthy women aged 20–40 years...
Abstract Aortic dissection ( AD ) is a disease characterized by tear in the aortic intimal layer and separation of arterial wall. Some risk factors, such as hypertension Marfan syndrome, are well known , but role genetic factor largely unknown. In this study, we investigated relation between two single nucleotide polymorphisms SNPs identified genome‐wide association study . Approximately 177 patients diagnosed with through clinical evaluation imaging techniques 183 age‐ sex‐matched control...
The SARS-CoV-2 pandemic poses an unprecedented public health crisis. Accumulating evidences suggest that infection causes dysregulation of immune system. However, the unique signature early responses remains elusive. We characterized transcriptome rhesus macaques and mice infected with SARS-CoV-2. Alarmin S100A8 was robustly induced by in animal models as well COVID-19 patients. Paquinimod, a specific inhibitor S100A8/A9, could reduce inflammatory response rescue pneumonia substantial...
急性心脑血管意外多由于动脉粥样硬化易损斑块破裂继发血栓所致,新生血管是造成动脉粥样硬化斑块易损性的重要因素之一[1].超声造影(contrast-enhanced ultrasonography,CEUS)为微血管显影的新方法,能够检测颈动脉斑块内新生血管,在无创、实时、定性、定量评估斑块易损性、分析与临床疾病相关性及评价疗效方面发挥独到优势[2]。
Background: Dermatofibroma has various pathological classifications, some of which pose a risk recurrence and metastasis. Distinguishing these high-risk dermatofibromas based on appearance alone can be challenging. Therefore, high-frequency ultrasound may provide additional internal information lesions, helping to identify low-risk dermatofibroma early. Methods: In this retrospective study, 50 lesions were analyzed explore the correlation between clinical features level. Based their...
Background: Partial atrioventricular septal defect (P-AVSD) is a common congenital heart disease. Because of the presence left and right valve deformities shift in node cardiac conduction bundle, surgical repair P-AVSD difficult. This study was performed to compare effects on coronary sinus septum versus atrium during treatment for report our experiences regarding application on-pump beating surgery under mild hypothermia patients with P-AVSD.Materials Methods: The were analyzed...