A5101850722- Medicinal Plants and Neuroprotection
- Pain Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Neurological Disease Mechanisms and Treatments
- Autoimmune Bullous Skin Diseases
- Tea Polyphenols and Effects
- Parkinson's Disease Mechanisms and Treatments
- Tryptophan and brain disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Medicinal Plant Pharmacodynamics Research
- Cancer-related Molecular Pathways
- Dermatologic Treatments and Research
- RNA modifications and cancer
- Inflammatory Biomarkers in Disease Prognosis
- Ubiquitin and proteasome pathways
- Olfactory and Sensory Function Studies
- Sirtuins and Resveratrol in Medicine
- Ginkgo biloba and Cashew Applications
- Alzheimer's disease research and treatments
- Skin Diseases and Diabetes
- Humic Substances and Bio-Organic Studies
- Adenosine and Purinergic Signaling
- Neurological Disorders and Treatments
- Autophagy in Disease and Therapy
Xian Yang Central Hospital
2013-2019
The First People’s Hospital of Lianyungang
2013-2019
First Affiliated Hospital of Jinan University
2014
Guangdong Pharmaceutical University
2013
Second Affiliated Hospital of Harbin Medical University
2008
Harbin Medical University
2008
Resveratrol, a natural polyphenol found in red wine, has wide spectrum of pharmacological properties including antioxidative and antiaging activities. Beta amyloid peptides (Aβ) are known to involve cognitive impairment, neuroinflammatory apoptotic processes Alzheimer's disease (AD). Activation cAMP and/or cGMP activities can improve memory performance decrease the neuroinflammation apoptosis. However, it remains unknown whether enhancing effect resveratrol on AD associated disorders is...
Green tea is one of the most beverages with antioxidants and nutrients. As major components green tea, (-)-epicatechin gallate (ECG) was evaluated for its antioxidative properties in present study. Cell proliferation assay, tube formation, cell migration, apoptosis, autophagy were performed human brain microvascular endothelial cells (HBMVECs) after oxygen-glucose deprivation/reoxygenation (OGD/R) to investigate potential anti-ischemia/reperfusion injury ECG vitro. Markers oxidative stress...
// Xiaoyu Pan 1, * , Jiechun Chen 2, Weijie Wang 3, Ling 4 Lin Quan Ma 5 Jianbo Zhang 6 Lichao 7 Gang Meixi 7, # Hao Wu 8, Ruochuan Cheng 1 Department of Thyroid Surgery, The First Affiliated Hospital Kunming Medical University, Kunming, Yunnan Province, China 2 Neurology, Lianyungang second people’s Hospital, Lianyungang, Jiangsu 3 Neurosurgery, Huai’an People’s Nanjing Huai’an, Clinical Pharmacy, Hangzhou Hangzhou, Zhejiang Pharmaceutical Sciences, School Pharmacy...
Objective: To investigate the effect of fasting plasma glucose (FPG) and glycosylated hemoglobin (HbAlc.) levels on thrombolytic therapy in patients with acute cerebral infarction type 2 diabetes mellitus.
 Methods: A total 135 were selected for this study. They divided into study group (n=70, & mellitus) control (n=65, but no mellitus). All underwent thrombolysis treatment Alteplase injection. The evaluated by national institutes health stroke scale (NIHSS) score, modified Rankin...
iASPP is an inhibitory member of the apoptosis-stimulating proteins P53 (ASPP) family. over expressed in several malignant tumors and potentially affects cancer progression. However, expression potential role oral tongue squamous cell carcinoma (OTSCC) have not been addressed. In our study, we detected OTSCC by immunohistochemistry. up-regulated tissues. Moreover, clinical pathology specimens, found that increased correlates with poor differentiation lymph node metastasis. Using...
Experimental allergic encephalomyelitis is a mouse model of human multiple sclerosis with similar pathology and pathogenesis. Th1 cells play an important role in the pathogenesis experimental encephalomyelitis. This study determined potential effect programmed cell death 1 ligand induced by injecting myelin oligodendrocyte glycoprotein, complete Freund's adjuvant Bordetella pertussis toxin into C57BL/6J mice. mice developed disease showed inflammatory changes central nervous system...
Background: Levodopa treatment is the gold standard in Parkinson’s disease but has risk of dyskinesias. Selegiline delays introduction levodopa and pramipexole used as a symptomatic disease. Objectives: This study aimed to compare effectiveness with selegiline Parkinson's patients. Methods: Data regarding motor cognitive impairments plasma phospholipids 500 Chinese patients confirmed from medical records 1 January 2015 June 2016 were retrospectively evaluated. Patients received either (PP...
Objective To evaluate the efficacy and safety of centella triterpenes cream(R) for treating crow's feet.Methods A double-blind,randomized,vehicle-controlled 12-week study was conducted.Centella applied to lateral canthus on one side (treatment side) vehicle-(c)ontrol cream other (control 3 times daily.Efficacy evaluated based an investigator-blinded assessment,subject self-blinded assessment a quantitative analysis by Visioscan(R)VC98 at baseline,4,8,12 weeks after beginning...
Objective To investigate the predictive value of neutrophil to lymphocyte ratio (NLR) on admission for early neurological deterioration (END) in patients with lacunar stroke. Methods Patients acute stroke admitted Department Neurology, Second People's Hospital Lianyungang from June 2015 October 2017 were enrolled retrospectively. END was defined as an increase ≥2 National Institutes Health Stroke Scale (NIHSS) score within 72 h admission. Multivariate logistic regression analysis used...