Chao Xu

ORCID: 0000-0001-9943-8659
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About
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Research Areas
  • Aquaculture Nutrition and Growth
  • Aquaculture disease management and microbiota
  • Reproductive biology and impacts on aquatic species
  • Adipose Tissue and Metabolism
  • Aquatic life and conservation
  • Physiological and biochemical adaptations
  • Synthesis and Biological Activity
  • Microbial Natural Products and Biosynthesis
  • Metabolism, Diabetes, and Cancer
  • Pancreatic function and diabetes
  • Protein Hydrolysis and Bioactive Peptides
  • Animal Nutrition and Physiology
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Peroxisome Proliferator-Activated Receptors
  • Fish biology, ecology, and behavior
  • Ubiquitin and proteasome pathways
  • Mitochondrial Function and Pathology
  • Cancer-related molecular mechanisms research
  • Liver Disease Diagnosis and Treatment
  • Synthetic Organic Chemistry Methods
  • Acute Myeloid Leukemia Research
  • Endoplasmic Reticulum Stress and Disease
  • Hematopoietic Stem Cell Transplantation
  • Sirtuins and Resveratrol in Medicine

South China Agricultural University
2014-2025

Minhang District Central Hospital
2024

Fudan University
2024

Jiangsu Academy of Agricultural Sciences
2021-2024

Soochow University
2011-2023

Shandong First Medical University
2015-2023

Shandong Provincial Hospital
2023

Shandong University
2023

First Affiliated Hospital of Soochow University
2011-2023

Changchun University of Chinese Medicine
2023

Tanshinone is a group of active diterpenes, which are widely used in the treatment cardiovascular disease. In this study, methyl jasmonate (MJ) and salicylic acid (SA) were to investigate their effects on tanshinone accumulation biosynthetic gene expression hairy roots geranylgeranyl diphosphate synthase (SmGGPPS) overexpression line (G50) Salvia miltiorrhiza. High-performance liquid chromatography analysis showed that total content G50 was obviously increased by 3.10-fold (11.33 mg/g) with...

10.1002/bab.1236 article EN Biotechnology and Applied Biochemistry 2014-04-29

This study investigated the effects of resveratrol on growth performance, energy sensing, glycolipid metabolism and glucose insulin tolerance blunt snout bream Megalobrama amblycephala fed high-carbohydrate diets. Fish (39.44 ± 0.06 g) were randomly three diets: a control diet (30% carbohydrate), (HC, 41% HC supplemented with 0.04% (HCR) for 12 weeks. had significantly high values nitrogen retention efficiency, hepatosomatic index, intraperitoneal fat ratio, whole-body lipid content glycogen...

10.3389/fphys.2018.01258 article EN cc-by Frontiers in Physiology 2018-09-11

There is evidence that osteoarthritis (OA) associated with ferroptosis which a kind of lipid peroxidation-related cell death. Theaflavin-3,3 <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M2"> <a:mo>′</a:mo> </a:math> -digallate(TF3), polyphenol compound extracted from black tea, possesses antioxidative and anti-inflammatory properties, but its effects on chondrocyte in remain unclear. Our present study aims at exploring the protective role underlying mechanisms TF3 against...

10.1155/2022/3531995 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-11-17

Non-alcoholic fatty liver disease (NAFLD) is characterized by excess accumulation of triglycerides within the liver. However, whether circulating levels and cholesterol transported in triglyceride-rich lipoproteins (remnant cholesterol, remnant-C) are related to occurrence NAFLD has not yet been studied. This study aims assess association remnant-C with a Chinese cohort middle aged elderly individuals.All subjects current from 13,876 individuals who recruited Shandong REACTION study. We...

10.3389/fendo.2023.1098078 article EN cc-by Frontiers in Endocrinology 2023-05-05

To develop a more sensitive immunoassay for malachite green (MG) and leucomalachite (LMG), we identified the immunocomplex binding phage-borne peptides use in noncompetitive phage anti-immunocomplex assay (PHAIA). An anti-LMG monoclonal antibody (mAb) was used to select from circular random eight-amino-acid phage-displayed library. After three rounds of panning-elution, five that bound LMG–mAb were obtained. One peptide clones resulted an with highest sensitivity chosen further research. The...

10.1021/jf5019824 article EN publisher-specific-oa Journal of Agricultural and Food Chemistry 2014-07-31

Acrylamide (ACR) is generated during thermal processing of carbohydrate-rich foods at high temperature and can directly enter the body through ingestion, inhalation skin contact. The toxicity ACR has been widely studied. main results these studies show that exposure to cause neurotoxicity in both animals humans, reproductive carcinogenicity rodent animal models. However, mechanism not studied by metabolomics approaches, effect on autophagy remains unknown. Here, U2OS cell were treated with 6...

10.1016/j.ecoenv.2020.111543 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2020-11-09

This study evaluated the effects of different lipid sources-fish oil (FO), soybean oil, rapeseed and palm oil-on growth muscle quality golden pompano (Trachinotus ovatus) cultured in offshore cages for 10 weeks. Three diets (D1-D3) were formulated: D1 used only fish D2 blended fish, D3 combined oils. Fish group showed highest weight gain, specific rate, protein content, significantly outperforming D3. No significant differences content or edible found between groups. had levels long-chain...

10.3390/foods14050788 article EN cc-by Foods 2025-02-25

Deoxynivalenol (DON) is a class of mycotoxin produced in cereal crops infected with Fusarium graminearum species complex (FGSC). In China, FGSC mainly includes asiaticum and F. graminearum. DON belongs to the trichothecenes poses serious threat safety health humans animals. Succinate dehydrogenase inhibitors (SDHIs) are fungicides that act on succinate inhibit respiration pathogenic fungi. this study, fungicidal activities five SDHIs, including fluopyram, flutolanil, boscalid,...

10.3390/toxins11050272 article EN cc-by Toxins 2019-05-15

We aimed to investigate the effect of xylooligosaccharides (XOS) on growth performances and lipid metabolism common carp fed high-fat diets. 192 fish were randomly distributed into 24 tanks six groups (four replicates) with control diet, diet (HFD) HFD supplemented 5, 10, 20 30 g/kgXOS respectively for 8 weeks. Fish 10 g/kg XOS obtained higher final body weight, weight gain, specific rate protein efficiency ratio compared those HFD, while feed conversion showed opposite trend. hepatosomatic...

10.1111/anu.12678 article EN Aquaculture Nutrition 2018-04-10

A 12-wk trial was conducted to compare the tolerance of tilapia high carbohydrate and lipid diets. Three isonitrogenous isoenergetic diets, whose levels were following: 35.0% 8% (control), 44.2% 4% (D1, carbohydrate), 25.8% 12% (D2, lipid), respectively. hundred tilapias (27 ± 0.11 g) fed diets for 10 wk (4 replicates per group); 72 fish from D1 group continually (D1D1) D2 (D2D2) diet 2 (3 each group) evaluate tilapia's capacity tolerate Another 36 (D1D2) comparison with D1D1 D2D2 groups. In...

10.1016/j.aninu.2023.01.007 article EN cc-by-nc-nd Animal nutrition 2023-01-23
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