A5038519122- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal Development and Disorders
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Nasolacrimal Duct Obstruction Treatments
- Ocular Surface and Contact Lens
- Cancer and Skin Lesions
- Systemic Lupus Erythematosus Research
- Dental materials and restorations
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Neuroscience and Neural Engineering
- Optical Coherence Tomography Applications
- Dental Trauma and Treatments
- Drug-Induced Ocular Toxicity
- Gaze Tracking and Assistive Technology
- Hydrology and Watershed Management Studies
- Adenosine and Purinergic Signaling
- Head and Neck Surgical Oncology
- Traumatic Ocular and Foreign Body Injuries
- Urban Stormwater Management Solutions
- Dental Radiography and Imaging
- Neuroscience and Neuropharmacology Research
Klinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg
2022-2025
Ophthalmology Clinic
2022-2025
University Hospital Münster
2022-2025
University of Münster
2004-2024
Bielefeld University
2022
University of Pennsylvania
2005
Ivoclar Vivadent (Liechtenstein)
2005
Ivoclar Vivadent (Germany)
2004
University of Cologne
2000
The Preserflo MicroShunt represents a novel glaucoma treatment device, necessitating long-term follow-up data to accurately assess its efficacy. aim of this study is report real-world heterogenous cohort who received implantation at specialized clinic. A total 160 eyes patients underwent were retrospectively enrolled in study. Patient characteristics, as well success and failure rates, assessed. numbers adverse events revision procedures recorded, along with any reduction supplementary...
The retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age-related macular degeneration (AMD) and other degenerative diseases. introduction healthy RPE cell cultures into subretinal space offers a potential treatment strategy. aim this study was long-term culture characterisation cells on nanofiber scaffolds. Nanofiber scaffolds consisting polycaprolactone (PCL) collagen were prepared by electrospinning. Porcine maintained PCL scaffolds, PCL-collagen controls at...
Zusammenfassung Einleitung Oregis, das digitale Register der Deutschen Ophthalmologischen Gesellschaft (DOG), dient als zentrale Plattform zur Erfassung und Analyse von Versorgungsdaten in Augenheilkunde Deutschland. Ziel oregis ist es, ein umfassendes Bild aktuellen Versorgungslage zu schaffen die Versorgungsforschung durch Real-World-Daten aus ambulanten stationären Einrichtungen fördern. Seit seiner Einführung im Jahr 2020 verzeichnet eine kontinuierliche Ausweitung Datenbasis,...
Background/Objectives: To compare the efficacy and safety of Hydrus® Microstent iStent inject® W implants, in combination with phacoemulsification, for lowering intraocular pressure (IOP) patients glaucoma a real-world clinical setting. Methods: This retrospective, single-center study analyzed medical records who underwent either or implantation combined cataract surgery at University Hospital Muenster, Germany. Key outcome measures included absolute relative IOP reduction, reduction topical...
Background/Objectives: Leber hereditary optic neuropathy (LHON) is often misdiagnosed in its early stages as idiopathic single isolated neuritis (SION) or multiple-sclerosis-associated (MS-ON) due to the young age of patients, subacute vision loss, and central visual field defect. The aim this retrospective study was evaluate changes peripapillary RNFL GCLT over time patients with LHON, MS-ON, SION order differentiate from (ON) disease. Methods: Patients LHON ON (either first symptom...
To investigate whether vaccination against SARS-CoV-2 is associated with the onset of retinal vascular occlusive disease (RVOD).In this multicentre study, data from patients central and branch vein occlusion (CRVO BRVO), artery (CRAO BRAO), anterior ischaemic optic neuropathy (AION) were retrospectively collected during a 2-month index period (1 June-31 July 2021) according to defined protocol. The relation any previous was documented for consecutive case series. Numbers RVOD COVID-19...
Digitalization in medicine, especially the electronic documentation of patient data, is revolutionizing healthcare systems worldwide. The evaluation real-world data collected under everyday conditions presents opportunities but also challenges. Electronic medical registries provide a means to compile extensive for scientific inquiries. Oregis first nationwide digital registry health services research established by German Ophthalmological Society (DOG). Intravitreal operative medicinal...
Recent studies have questioned the traditional view, which regards Coats disease as a strictly unilateral entity. Applying optical coherence tomography angiography, this prospective, monocentric study investigates quantitative capillary changes of macula associated with disease.Twenty-four eyes (4 untreated, 8 pre-treated) 12 patients stage 2 (age range: 9-61 years) and 15 healthy, age-matched controls from University Muenster Medical Center, Germany received macular angiography measurements...
This case report describes a 78-year-old patient who developed tear of the retinal pigment epithelium (RPE) during faricimab (Vabysmo®) therapy. After three consecutive intravitreal aflibercept (Eylea®) injections with persistent disease activity, therapy was switched to faricimab. The experienced in RPE 4 weeks postinjection. We first published development after injection neovascular age-related macular degeneration. Faricimab has new target structure angiopoietin-2 receptor addition VEGF....
Background/Objectives: This study aims to investigate the long-term effect of inactive systemic lupus erythematosus (SLE) on retinal microcirculation measured via optical coherence tomography angiography (OCT-A). Methods: Twenty-four eyes 24 patients with SLE under hydroxychloroquine (HCQ) therapy were included. The OCT-A data (mainly vessel density (VD) and foveal avascular zone (FAZ) superficial deep capillary plexus (SCP, DCP) choriocapillaris (CC)) analyzed compared between baseline...
Rheumatoid arthritis (RA) is the most common inflammatory joint disease, and hydroxychloroquine (HCQ) an established treatment. The extent to which HCQ impacts ocular microvascular vessel density (VD) in patients with RA without evidence of retinopathy has not yet been conclusively clarified. main aim this study was evaluate VD measured by optical coherence tomography angiography (OCTA) treated HCQ.The data 3 × mm OCT angiogram (RTVue XR Avanti, Optovue Inc., Fremont, California, USA) as...
It has long been speculated whether the presence of a cilioretinal artery (CRA) can influence development glaucomatous damage in patients with open-angle glaucoma. Studies involving healthy have shown change flow density (FD) depending on CRA. Similarly, studies that compared optical coherence tomography angiography (OCTA) results controls and glaucoma cohorts identified reduction FD certain retinal layers for patients. These observations raise question is altered CRA, possible implications...
Glaucoma is one of the leading causes irreversible blindness globally and characterized by gradual loss retinal ganglion cells. The primary risk factor for development progression glaucoma increased intraocular pressure (IOP). Numerous surgical interventions exist to lower IOP should conservative therapy fail. One trend in recent years has been minimally invasive surgery (MIGS) as an alternative traditional methods. ISTENT inject® ab interno trabecular micro-bypass implant designed be...
Zusammenfassung Hintergrund Das Susac-Syndrom (SS) stellt eine Endotheliopathie der Gefäße im Bereich des zentralen Nervensystems dar. Die Beteiligung Netzhaut spielt in Krankheitsmanifestation zentrale Rolle. Ziel Arbeit dieser Fall-Kontroll-Studie ist die Untersuchung makulären Gefäßstruktur bei Patienten mit chronischem SS Vergleich zu Kontrollpersonen mittels optischer Kohärenztomographie Angiographie (OCTA). Material und Methoden Es wurden 12 Augen von Susac-Patienten altersgleichen...
Abstract Congenital nasolacrimal duct obstruction (CNLDO) is the most common cause of epiphora in first year life. In addition to conservative therapy, there are several invasive methods available. The aim this retrospective study was conduct a long-term follow-up bicanalicular lacrimal intubation as primary intervention large cohort patients with CNLDO. electronic medical records 487 CNLDO who underwent tube were reviewed. To determine outcomes, telephone interview conducted. A total 328...
Abstract Background In times of omnipresent digitization and big data, telemedicine electronic case files (ECFs) are gaining ground for networking between players in the health care sector. context SALUS study, this approach is applied practice form platforms to display process disease-relevant data glaucoma patients. Objectives The ECF designed implemented support acquisition presentation, monitoring, outcome control patients suffering from a clinical setting. Its main aim provide means...
Abstract The EyeMatics project, embedded as a clinical use case in Germany’s Medical Informatics Initiative, is large digital health initiative ophthalmology. objective to improve the understanding of treatment effects intravitreal injections, most frequent procedure treat eye diseases. To achieve this, valuable patient data will be meaningfully integrated and visualized from different IT systems hospital sites. emphasizes governance framework that actively involves representatives, strictly...
Introduction: Glaucoma, one leading cause of irreversible vision loss worldwide, is primarily caused by elevated intraocular pressure (IOP). Recently, minimally invasive glaucoma surgeries (MIGSs) have become popular due to their shorter surgical times, tissue-sparing nature, and faster recovery. One such MIGS, the Hydrus® nickel–titanium alloy Microstent, helps lower IOP improving aqueous humor outflow. The NIDEK GS-1 automated 360° gonioscope provides advanced imaging chamber angle for...