A5014253259- Ethics in Clinical Research
- Electronic Health Records Systems
- Data Quality and Management
- Clinical practice guidelines implementation
- Biomedical Ethics and Regulation
- Medical and Health Sciences Research
- Retinal Imaging and Analysis
- Palliative Care and End-of-Life Issues
- Bioinformatics and Genomic Networks
- Privacy-Preserving Technologies in Data
- Digital Imaging in Medicine
- Healthcare cost, quality, practices
- Retinal Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Digitalization, Law, and Regulation
- Healthcare Decision-Making and Restraints
- Gaze Tracking and Assistive Technology
- Biomedical Text Mining and Ontologies
- Health and Medical Studies
- Machine Learning in Healthcare
- Patient-Provider Communication in Healthcare
- Patient Dignity and Privacy
- Glaucoma and retinal disorders
Universitätsmedizin Greifswald
2020-2024
Universität Greifswald
2023
Humboldt-Universität zu Berlin
2020
Charité - Universitätsmedizin Berlin
2020
Freie Universität Berlin
2020
COVID-19 has challenged the healthcare systems worldwide. To quickly identify successful diagnostic and therapeutic approaches large data sharing are inevitable. Though organizational clinical abundant, many of them available only in isolated silos largely inaccessible to external researchers. overcome tackle this challenge university medicine network (comprising all 36 German hospitals) been founded April 2020 coordinate action plans, strategies collaborative research activities. 13...
Clinical trials are the gold standard for advancing medical knowledge and improving patient outcomes. For their success, an appropriately sized cohort is required. However, recruitment remains one of most challenging aspects clinical trials. Information technology (IT) support systems-for instance, systems-may help overcome existing challenges improve rates, when customized to user needs environment.The goal our study describe status quo processes identify requirements development a...
The Federal Ministry of Education and Research Germany (BMBF) funds a network university medicines (NUM) to support COVID-19 pandemic research at national level. "COVID-19 Data Exchange Platform" (CODEX) as part NUM establishes harmonised infrastructure that supports use datasets. broad consent (BC) the Medical Informatics Initiative (MII) is agreed by all German federal states forms legal base for data processing. All 34 participating hospitals (NUM sites) work upon infrastructural well...
Abstract Background The consent management is an essential component for supporting the implementation of consents and withdrawals thus, realisation patient’s rights. In MIRACUM, one four consortia Medical Informatics Initiative (MII), ten university hospitals intend to integrate generic Informed Consent Service® (gICS) in their Data Integration Center (DIC). To provide a tool that supports local workflows MIRACUM sites, gICS should be improved. Methods We used three standardised...
Abstract Background The identity management is a central component in medical research. Patients are recruited from various sites, which requires an error tolerant record linkage method, to ensure that patients registered only once. In large research projects or institutions, the has deal with several thousands millions of patients. environments numbers register process could lead high runtimes caused by linkage. Central Biomaterial Bank Charité (ZeBanC) searched for solution, can handle...
Availability and accessibility are important preconditions for using real-world patient data across organizations. To facilitate enable the analysis of collected at a large number independent healthcare providers, syntactic- semantic uniformity need to be achieved verified. With this paper, we present transfer process implemented Data Sharing Framework ensure only valid pseudonymized is transferred central research repository feedback on success or failure provided. Our implementation used...
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI
In German and international research networks different approaches concerning patient consent are applied. So far it is time-consuming to find out what extent data from these can be used for a specific project. To make the contents of consents queryable, we aimed permission-based approach (Opt-In) that map both permission withdrawal as well queryable beyond project boundaries.
Abstract The EyeMatics project, embedded as a clinical use case in Germany’s Medical Informatics Initiative, is large digital health initiative ophthalmology. objective to improve the understanding of treatment effects intravitreal injections, most frequent procedure treat eye diseases. To achieve this, valuable patient data will be meaningfully integrated and visualized from different IT systems hospital sites. emphasizes governance framework that actively involves representatives, strictly...
Abstract BackgroundThe Federal Ministry of Research and Education funded the Network University Medicine for establishing an infrastructure pandemic research. This includes development a COVID-19 Data Exchange Platform (CODEX) that provides standardised harmonised data sets Nearly all university hospitals in Germany are part project transmit medical from local integration centres to CODEX platform. The on person has been collected at several sites is be made available platform merged form....
ObjectiveIn numerous German and international research networks projects that collect personal health data, different approaches to how a participant consent looks like exist. In Germany, data usage for medical is thus far consented in the Opt-In system. order make contents of consents queryable, we have searched purely permission-based approach, which can map both permission withdrawal as well them queryable without overlaps.MethodsQuery solutions from two were compared such way overlapping...
Record linkage means linking data from multiple sources. This approach enables the answering of scientific questions that cannot be addressed using single sources due to limited variables. The potential linked for health research is enormous, as it can enhance prevention, treatment, and population policies. Due sensitivity data, there are strict legal requirements prevent misuse. However, these also limit use research, thereby hindering innovations in prevention care. Also, comprehensive...
Abstract Background The Federal Ministry of Education and Research (BMBF) funds a network university medicines (NUM) to support COVID-19 pandemic research at national level. “COVID-19 Data Exchange Platform” (CODEX) as part NUM establishes harmonised infrastructure that supports decentral but standardised provision well federated combination use datasets. broad consent (BC) the Medical Informatics Initiative (MII) is agreed by all German federal states forms legal base for such data...
Abstract Background The Federal Ministry of Education and Research Germany (BMBF) funds a network university medicines (NUM) to support COVID-19 pandemic research at national level. “COVID-19 Data Exchange Platform” (CODEX) [1] as part NUM establishes harmonised infrastructure that supports use datasets. broad consent (BC) the Medical Informatics Initiative (MII) is agreed by all German federal states forms legal base for data processing. All 34 participating hospitals (NUM sites) work upon...
<sec> <title>BACKGROUND</title> Clinical trials are the gold standard for advancing medical knowledge and improving patient outcomes. For their success, an appropriately sized cohort is required. However, recruitment remains one of most challenging aspects clinical trials. Information technology (IT) support systems—for instance, systems—may help overcome existing challenges improve rates, when customized to user needs environment. </sec> <title>OBJECTIVE</title> The goal our study describe...