A5100354619- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Genetics and Neurodevelopmental Disorders
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Migraine and Headache Studies
- Face Recognition and Perception
- Language Development and Disorders
- Transcranial Magnetic Stimulation Studies
- Ophthalmology and Eye Disorders
- Memory and Neural Mechanisms
- Trigeminal Neuralgia and Treatments
- Regulation of Appetite and Obesity
- Bioinformatics and Genomic Networks
- Dementia and Cognitive Impairment Research
- EEG and Brain-Computer Interfaces
- Neural Networks and Applications
- Computational Drug Discovery Methods
- Sleep and Wakefulness Research
- Reading and Literacy Development
- Williams Syndrome Research
- Neurological disorders and treatments
- Electrochemical Analysis and Applications
Nanjing Drum Tower Hospital
2017-2025
Tianjin Medical University General Hospital
2015-2023
Fudan University
2022
State Key Laboratory of Medical Neurobiology
2022
Taiyuan University of Technology
2022
Capital Medical University
2021
Sichuan University
2018
West China Hospital of Sichuan University
2018
University of Minnesota
2011
Long term video game players (VGPs) exhibit superior visual and motor skills compared with non-video control subjects (NVGCs). However, the neural basis underlying enhanced behavioral performance remains largely unknown. To clarify this issue, present study whiter matter integrity within corticospinal tracts (CST), longitudinal fasciculus (SLF), inferior (ILF), fronto-occipital (IFOF) between VGPs NVGCs using diffusion tensor imaging. Compared NVGCs, voxel-wise comparisons revealed...
Major depressive disorder is a common comorbidity in migraineurs. Depression may affect the progression and prognosis of migraine. Few studies have examined brain function migraineurs that cause this comorbidity. Here, we aimed to explore depression-related abnormalities intrinsic activity interictal with comorbid depression using resting-state functional magnetic resonance imaging.Significant main effects migraine provided evidence jointly affected left medial prefrontal cortex, which was...
Abstract Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI) and independent component analysis to evaluate for alterations brain activation connectivity (FC) networks determine their associations with clinical variables. Twenty...
Disruptions in brain connectivity have been widely reported Alzheimer's disease (AD). Morphometric similarity (MS) mapping provides a new way of estimating structural by interregional correlation T1WI- and DTI-derived parameters within individual brains. Here, we aimed to identify AD-related MS changing patterns genes related the changes further explored molecular cellular mechanism underlying AD. Both 3D-T1WI DTI data 106 AD patients well-matched healthy elderly individuals from ADNI...
The Brodmann area (BA)-based map is one of the most widely used cortical maps for studies human brain functions and in clinical practice; however, molecular architecture BAs remains unknown. present study provided a global multiregional proteomic cerebral cortex by analyzing 29 BAs. These were grouped into 6 clusters based on similarities patterns: motor sensory cluster, vision auditory Broca's Wernicke's cingulate heterogeneous function cluster. We identified 474 cluster-specific 134...
The analysis of resting-state fMRI signals usually focuses on the low-frequency range/band (0.01−0.1 Hz), which does not cover all aspects brain activity. Studies have shown that distinct frequency bands can capture unique fluctuations in activity, with high-frequency (>0.1 Hz) providing valuable information for diagnosis schizophrenia. We hypothesized it is meaningful to study dynamic reconfiguration schizophrenia through different frequencies. Therefore, this used functional magnetic...
Abstract Disruptions of brain connectivity have been widely reported in Alzheimer's disease (AD). Morphometric similarity (MS) mapping provides a new way estimating structural by inter-regional correlation T1WI and DTI derived parameters within individual brains. Here, we aimed to identify AD-related MS changing patterns genes related the changes further explore molecular cellular mechanism underlying AD. Both 3D-T1WI data 106 AD patients well-matched healthy elders from ADNI database were...
Type 2 diabetes (T2DM) is a polygenic metabolic disorder that accelerates brain aging and harms cognitive function. The underlying mechanism of T2DM-related functional changes has not been clarified.Resting-fMRI data were obtained from 99 T2DM 109 healthy controls (HCs). Resting-state connectivity networks (RSNs) separated using the Independent Component Analysis (ICA) method, (FC) differences between patients HCs within RSNs detected. A partial least squares (PLS) regression was used to...
Speech perception research has been greatly enriched by technical advancement in neuroimaging. Here electroencephalography (EEG) and magnetoencephalography (MEG) data from infant adult subjects are reported to demonstrate the feasibility importance of distributed source estimation time-frequency analysis understanding time-dependent nature cortical specialization integration speech processing. Advantages limitations current approaches for EEG MEG discussed relation functional magnetic...
Increasing evidence has revealed that the rostromedial tegmental area (RMTg) mediates many behaviors, including sleep and addiction. However, presynaptic patterns governing activity of γ-aminobutyric acid-releasing (GABAergic) neurons, main neuronal type in RMTg, have not been defined. Here, we used cell-type-specific retrograde trans-synaptic rabies viruses to map quantify monosynaptic afferents RMTg GABAergic neurons mouse whole brains. We identified 71 ascending projection brain regions....
Naturalistic fMRI has been suggested to be a powerful alternative for investigations of human brain function. Stimulus-induced activation playing an essential role in fMRI-based function analyses. Due the complexity stimuli, however, detection activations induced by naturalistic stimuli (AINSs) tricky problem, as AINS cannot detected simply model-driven way. In this study, we proposed method detect pseudo Inspired strategy utilizing commonalities among brains exposed same inter-subject...
Patients with Parkinson's disease (PD) mainly manifested dyskinesia and lack of information processing ability. Resting-state fMRI (rs-fMRI) brain signal has been used to study activity. However, few studies apply complexity analysis functional imaging. It is still not clear whether Prodromal (PPD) patients PD have abnormal complexity, related the frequency band. So we explored 21 normal controls (NCs), 26 PPD patients, 47 in four bands based on fuzzy entropy (FE). In slow 3 2 bands, higher...
Abstract The Brodmann area (BA)-based map is one of the most widely used cortical maps for studies human brain functions and in clinical practice; however, molecular architecture BAs remain unknown. present study provided a global multiregional proteomic cerebral cortex by analyzing 29 BAs. These were grouped into 6 clusters based on similarities patterns: motor sensory cluster, vision auditory cluster Broca’s area, Wernicke’s cingulate heterogeneous function cluster. We identified 474...