A5103004699- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Viral Infections and Immunology Research
- Medical Imaging Techniques and Applications
- AI in cancer detection
- Air Quality and Health Impacts
- RNA regulation and disease
- Psychosomatic Disorders and Their Treatments
- Bone Metabolism and Diseases
- Digital Imaging for Blood Diseases
- Radiation Dose and Imaging
- T-cell and Retrovirus Studies
- Medical Image Segmentation Techniques
- Virology and Viral Diseases
- Global Cancer Incidence and Screening
- Radiomics and Machine Learning in Medical Imaging
- Bone health and osteoporosis research
- Microbial Fuel Cells and Bioremediation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Time Series Analysis and Forecasting
- RNA modifications and cancer
- Immune responses and vaccinations
- Psychosocial Factors Impacting Youth
- Occupational and environmental lung diseases
- Multiple and Secondary Primary Cancers
Tianjin Medical University General Hospital
2021-2024
Northwest A&F University
2024
Tongji Hospital
2020-2023
Tongji University
2020-2023
China Tobacco
2022
West Virginia State University
2021
Tumor Hospital of Xinjiang Medical University
2014-2020
Xinjiang Medical University
2014-2020
Peking Union Medical College Hospital
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic HFMD has been a public health problem Asia-Pacific region for decades, no vaccine effective antiviral medicine are available. Curcumin used as traditional centuries to treat diversity disorders including viral infections. In this study, we demonstrated that curcumin showed potent effect again EV71. Vero cells infected with EV71, addition significantly suppressed...
Background Understanding the effects of demographic drivers on lung cancer mortality trends is critical for control. We have examined at global, regional, and national levels. Methods Data death were extracted from Global Burden Disease (GBD) 2019. Estimated annual percentage change (EAPC) in age-standardized rate (ASMR) all-cause calculated to measure temporal 1990 Decomposition analysis was used analyze contributions epidemiological mortality. Results Despite a non-significant decrease...
Abstract Background Volatile organic compounds (VOCs) encompass hundreds of high production volume chemicals and have been reported to be associated with adverse respiratory outcomes such as chronic obstructive pulmonary disease (COPD). However, research on the combined toxic effects exposure various VOCs COPD is lacking. We aimed assess effect VOC metabolite mixture risk in a large population sample. Methods assessed 5997 adults from National Health Nutrition Examination Survey (NHANES)...
Little is known about trends in the lung cancer burden from disease that can be attributed to occupational carcinogens China.Data regarding China were extracted Global Burden of Disease (GBD) study 2019. Joinpoint regression analysis and an age-period-cohort (APC) conducted estimate trend as a result 1990 A Bayesian APC model was used predict until 2044.The average annual percentage changes age-standardized summary exposure values (SEVs) carcinogens, well population attributable fraction...
ABSTRACT Objective This study aimed to validate the Chinese version of Somatic Symptom Disorder–B Criteria Scale (SSD-12) in an outpatient sample from general hospitals and determine diagnostic performance SSD-12 as a screening tool for somatic symptom disorder (SSD). Methods The was completed by 699 outpatients nine during 16-month period (2016–2018). SSD section Structured Clinical Interview DSM Disorders, Fifth Edition, Research Version, used accuracy (criterion validity). construct...
Somatic symptom disorder (SSD) is a new diagnosis introduced into the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), which expected to solve diagnostic difficulties patients with medically unexplained symptoms. Based on previous work, this review aims comprehensively synthesise updated evidence related SSD from recent years in English publications and, more extensively, data published Chinese language journals. The scoping update was based an earlier included...
Co-administration of vaccines could be an efficient strategy to increase vaccination uptake and reduce the number clinic visits. This randomized controlled study aimed evaluate immunogenicity safety enterovirus 71 (EV71) vaccine co-administered with measles-mumps-rubella (MMR) live-attenuated Japanese encephalitis (LA-JEV). A total 372 healthy infants were randomly assigned in a 1:1:1 ratio receive simultaneous administration EV71 (dose 1) MMR on d 0 2) LA-JEV 30 (Group 1); 30, respectively...
Abstract Disruptions of brain connectivity have been widely reported in Alzheimer's disease (AD). Morphometric similarity (MS) mapping provides a new way estimating structural by inter-regional correlation T1WI and DTI derived parameters within individual brains. Here, we aimed to identify AD-related MS changing patterns genes related the changes further explore molecular cellular mechanism underlying AD. Both 3D-T1WI data 106 AD patients well-matched healthy elders from ADNI database were...
Diabetic kidney disease (DKD), a prevalent complication of diabetes mellitus, is often associated with acute injury (AKI). Thus, the development preventive and therapeutic strategies crucial for delaying progression AKI DKD.
Abstract Background C hest radiograph (CXR) is still one of the most commonly used diagnostic tools for chest diseases. In this cohort study, we attempted to investigate magnitude and temporal pattern lung cancer risk following abnormal CXR findings. Methods We conducted an extended follow‐up occupational screening in Yunnan, China. The associations between results from baseline screening, first four consecutive rounds all previous were analyzed using time‐varying coefficient Cox regression...
Premenstrual dysphoric disorder (PMDD) represents a significant psychiatric condition affecting women of reproductive age. It is characterized by cyclical emotional and physical symptoms that considerably impair psychosocial functioning. This study aims to investigate the prevalence PMDD among adult working identify associated etiological factors.
BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation, stress response and cell cycle so on. The expression status of are related certain tumor incidence prognosis. aim this study is explore the association with susceptibility lung adenocarcinoma.The data from 29 cases adenocarcinoma tissues matched pericancerous were...
It is an effective means for the early diagnosis of leukemia to study immature precursor cells in marrow pathological images by computer image processing technology. This paper proposed a new method about localization Pathological bone marrow. Firstly, we use modified OSTU binarize image; then process with morphological operations, combined their own characteristics and sizes cells; finally obtain right results cellular localization. Experimental show that this has better performance on...
Nowadays manual observation by microscopes is the major method to detect leukemia cells. However this takes much effort of doctors and depends on doctors' experience. This paper proposes a new locate immature precursor cells based distance transform internal structures At first, Otsu used binarize image; secondly, image processed through morphological operations; then an initial location in bone marrow pathological images done operation; fourthly, structure size are taken into consideration...
Abstract Background Lung cancer screening may provide a “teachable moment” for the smoking cessation and relapse prevention. However, impact of lung on initiation in non‐smokers has not been reported. Methods A baseline behavior survey was conducted 2000 participants who were screened by low‐dose computed tomography (LDCT) from 2014 to 2018. All re‐surveyed their 2019. Of these, 312 excluded, leaving 1688 final analysis. The rate non‐smokers, former smokers, abstinence current smokers...
This study explores the effect of different registration methods on placement accuracy and dosimetric analysis adaptive radiation therapy (ART) after breast conserving surgery for cancer, based cone-beam computed tomography (CBCT).Thirty cancer patients, who underwent surgery, were divided into three groups, with 10 patients in each group: automatic grayscale (group A), bony marker B), combined manual C). Three conducted before first radiotherapy, once a week under guidance CBCT. The...