- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Meningioma and schwannoma management
- Advanced MRI Techniques and Applications
- CNS Lymphoma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Salivary Gland Tumors Diagnosis and Treatment
- Bone and Joint Diseases
- Neurofibromatosis and Schwannoma Cases
- Spinal Cord Injury Research
- Pancreatic and Hepatic Oncology Research
- Medical Imaging Techniques and Applications
- Oral and Maxillofacial Pathology
- Hereditary Neurological Disorders
- Spondyloarthritis Studies and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Cancer, Hypoxia, and Metabolism
- Neurological diseases and metabolism
- Temporomandibular Joint Disorders
- Liver Disease Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
First Affiliated Hospital of Fujian Medical University
2015-2024
Fujian Medical University
2015-2024
Singapore General Hospital
2024
Regional Medical Center
2024
Huashan Hospital
2019
Fudan University
2019
Creative Commons
2017
<h3>BACKGROUND AND PURPOSE:</h3> <i>Isocitrate dehydrogenase</i> (<i>IDH</i>) has been shown to have both diagnostic and prognostic implications in gliomas. The purpose of this study was examine whether DWI DSC-PWI combined with conventional MR imaging could noninvasively predict <i>IDH</i> mutational status World Health Organization grade II III astrocytomas. <h3>MATERIALS METHODS:</h3> We retrospectively reviewed DWI, DSC-PWI, 42 patients Minimum ADC, relative maximum CBV values were...
The accurate grading of IDH-mutant astrocytoma is essential to make therapeutic strategies and assess the prognosis patients. purpose this study was investigate usefulness DWI, SWI DSC-PWI in astrocytoma.One hundred seven patients with who underwent were retrospectively reviewed. Minimum apparent diffusion coefficient (ADCmin), intratumoral susceptibility signal intensity(ITSS) maximum relative cerebral blood volume (rCBVmax) values assessed. ADCmin, ITSS rCBVmax compared between grade 2 vs....
Abstract Background and Purpose Conventional MRI is often difficult to distinguish between primary central nervous system lymphomas ( PCNSL s), high‐grade gliomas brain metastases due the similarity of their appearance. The aim this study was investigate whether susceptibility‐weighted imaging SWI ) has higher sensitivity than conventional in detecting hemorrhage s, metastases, can be used differentiate diagnosis these tumors. Methods number lesions with quantified by both MR ....
Currently, isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion are proven diagnostic biomarkers for both grade II III oligodendrogliomas (ODs). Non-invasive diffusion-weighted imaging (DWI), susceptibility-weighted (SWI), dynamic susceptibility contrast perfusion-weighted (DSC-PWI) widely used to provide physiological information (cellularity, hemorrhage, calcifications, angiogenesis) of neoplastic histology tumor grade. However, it is unclear whether DWI, SWI, DSC-PWI able...
<h3>BACKGROUND AND PURPOSE:</h3> Anaplastic pleomorphic xanthoastrocytoma, which has been recently defined as a distinct entity in the 2016 World Health Organization classification, may exhibit aggressive clinical behavior and relatively worse prognosis than xanthoastrocytoma. This study aimed to investigate whether there were any differences MR imaging characteristics between these 2 tumors. <h3>MATERIALS METHODS:</h3> retrospective included 9 patients with anaplastic xanthoastrocytoma 10...
To assess the usefulness of combined diffusion kurtosis imaging (DKI) and dynamic contrast-enhanced MRI (DCE-MRI) in differentiation parotid gland tumors.Seventy patients with 80 tumors who underwent DKI DCE-MRI were retrospectively enrolled divided into four groups: pleomorphic adenomas (PAs), Warthin (WTs), other benign (OBTs), malignant (MTs). quantitative parameters measured. The Kruskal-Wallis H test post hoc Bonferroni correction ROC curve used for statistical analysis.WTs demonstrated...
BackgroundTo assess the feasibility of multiparametric magnetic resonance imaging in predicting tumor recurrence nonenhancing peritumoral regions patients with glioblastoma at baseline.MethodsFifty-eight recurrent underwent imaging, including T2-weighted fluid-attenuated inversion recovery, diffusion-weighted and dynamic susceptibility contrast perfusion-weighted imaging. Nonenhancing were identified by coregistering preoperative post-recurrent images. Regions interest placed without to...
The performance of multiparametric MRI-based radiomics models for predicting H3 K27M mutant status in diffuse midline glioma (DMG) has not been thoroughly evaluated. optimal combination MRI and machine learning techniques remains undetermined. We compared the various across different sequences techniques.A total 102 patients with pathologically confirmed DMG were retrospectively enrolled (27 K27M-mutant 75 wild-type). Radiomics features extracted from eight sequences, 18 feature sets...
<h3>BACKGROUND AND PURPOSE:</h3> On DWI and DSC-PWI, hemangioblastomas brain metastases may exhibit different signal intensities depending on their cellularity angiogenesis. The purpose of this study was to evaluate whether a hemangioblastoma can be differentiated from single metastasis with DSC-PWI. <h3>MATERIALS METHODS:</h3> We retrospectively reviewed DWI, conventional MR imaging 21 patients 30 metastasis. Variables minimum ADC relative were acquired by the parameter maximum CBV, Minimum...
To evaluate the discriminative value of conventional magnetic resonance imaging between benign and malignant palatal tumors.Conventional features 130 patients with tumors confirmed by histopathologic examination were retrospectively reviewed. Clinical data findings assessed low-grade salivary gland tumors. The variables that significant in differentiating from lesions further identified using logistic regression analysis. Moreover, each common histologic entity statistically analyzed rest to...
Background Isocitrate dehydrogenase (IDH) mutation has diagnostic and prognostic values in glioblastomas. Peritumoral invasion of glioma cells is a cardinal feature Purpose To evaluate the contribution DWI DSC-PWI enhancing peri-enhancing region for discriminating glioblastomas IDH genotypes, combining two techniques compared with those region. Material Methods We retrospectively reviewed conventional MRI (cMRI), obtained from 10 patients IDH-mutated (IDH-m) 65 wild-type (IDH-w) Features...
Isocitrate dehydrogenase (IDH)-mutant lower-grade gliomas (LGGs) are further classified into two classes: with and without 1p/19q codeletion. IDH-mutant codeleted LGGs have better prognosis compared non-codeleted LGGs.To evaluate conventional magnetic resonance imaging (cMRI), diffusion-weighted (DWI), susceptibility-weighted (SWI), dynamic susceptibility contrast perfusion-weighted (DSC-PWI) for predicting codeletion status of LGGs.We retrospectively reviewed cMRI, DWI, SWI, DSC-PWI in 142...
Abstract Introduction The purpose of our study was to differentiate uterine carcinosarcoma (UCS) from endometrioid adenocarcinoma (EAC) by the multiparametric magnetic resonance imaging (MRI) features. Methods We retrospectively evaluated clinical and MRI findings in 17 patients with UCS 34 EAC proven histologically. following pathological features were evaluated: post- or pre-menopausal, presentation, invasion depth, FIGO stage, lymphaticmetastasis. tumor dimension, cystic degeneration...
Background Determining the absence or presence of peripancreatic lymph nodal metastasis (PLNM) is important to pathologic staging, prognostication, and guidance treatment in pancreatic ductal adenocarcinoma (PDAC) patients. Computed tomography MRI had a poor sensitivity diagnostic accuracy assessment PLNM. Purposes To develop validate 3 T primary tumor radiomics‐based nomogram from multicenter datasets for pretreatment prediction PLNM PDAC Study Type Retrospective. Subjects A total 251...