A5082973092- Genomics and Phylogenetic Studies
- Plant Pathogenic Bacteria Studies
- Plant-Microbe Interactions and Immunity
- Fungal and yeast genetics research
- Fermentation and Sensory Analysis
- Plant Pathogens and Fungal Diseases
- Neurobiology and Insect Physiology Research
- Legume Nitrogen Fixing Symbiosis
- Yeasts and Rust Fungi Studies
- Insect and Arachnid Ecology and Behavior
- Genetic diversity and population structure
- RNA and protein synthesis mechanisms
- Plant Disease Resistance and Genetics
- Plant and animal studies
- Bacterial Genetics and Biotechnology
- Plant Virus Research Studies
- Chromosomal and Genetic Variations
- RNA modifications and cancer
- Fungal Biology and Applications
- Banana Cultivation and Research
- Bacterial biofilms and quorum sensing
- Glioma Diagnosis and Treatment
- Protist diversity and phylogeny
- MRI in cancer diagnosis
- Evolution and Genetic Dynamics
South China Agricultural University
2011-2025
Southwest Hospital
2025
Army Medical University
2025
Shaanxi Normal University
2022-2025
Wuhan University
2025
China Jiliang University
2025
Vanderbilt University
2013-2024
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2020-2024
Fujian Medical University
2019-2024
First Affiliated Hospital of Fujian Medical University
2019-2024
Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. To investigate the genomic basis of explore new avenues vector control, we sequenced genomes 16 anopheline from diverse locations spanning ~100 million years evolution. Comparative analyses show faster rates gene gain loss, elevated shuffling on X chromosome, more intron losses, relative to Drosophila. Some determinants capacity,...
Abstract Water lilies belong to the angiosperm order Nymphaeales. Amborellales, Nymphaeales and Austrobaileyales together form so-called ANA-grade of angiosperms, which are extant representatives lineages that diverged earliest from lineage leading mesangiosperms 1–3 . Here we report 409-megabase genome sequence blue-petal water lily ( Nymphaea colorata ). Our phylogenomic analyses support Amborellales as successive sister all other angiosperms. The N. 19 transcriptomes reveal a Nymphaealean...
Abstract Understanding the phylogenetic relationships among yeasts of subphylum Saccharomycotina is a prerequisite for understanding evolution their metabolisms and ecological lifestyles. In last two decades, use rDNA multilocus data sets has greatly advanced our yeast phylogeny, but many deep remain unsupported. contrast, phylogenomic analyses have involved relatively few taxa lineages that were often selected with limited considerations covering breadth biodiversity. Here we used genome...
Ants are a highly successful family of insects that thrive in variety habitats across the world. Perhaps their best-known features complex social organization and strict division labor, separating reproduction from day-to-day maintenance care colony, as well discrimination against foreign individuals. Since these characteristics ants thought to be mediated by semiochemicals, thorough analysis signals, receptors detect them, is critical revealing mechanisms lead stereotypic behaviors. To...
Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to broad (generalists). Two general paradigms have been proposed explain this variation: (i) trade-offs between performance efficiency and breadth (ii) the joint influence of extrinsic (environmental) intrinsic (genomic) factors. We assembled genomic, metabolic, data nearly all known species ancient fungal subphylum Saccharomycotina (1154 yeast strains 1051 species), grown 24 different...
Lilies are economically important monocots known for their ornamental flowers, bulbs, and large genomes. The absence of genomic information has impeded evolutionary studies genome-based breeding efforts. Here, we present reference genomes Lilium sargentiae (lily, 35.66 Gb) Gloriosa superba (flame lily, 5.09 Gb). giant lily genome is shaped by recent long terminal repeat retroelements. Phylogenetic analysis reveals diverse, independent origins cultivars. Gene families involved in sucrose...
The sizes of the data matrices assembled to resolve branches tree life have increased dramatically, motivating development programs for fast, yet accurate, inference. For example, several different fast been developed in very popular maximum likelihood framework, including RAxML/ExaML, PhyML, IQ-TREE, and FastTree. Although these are widely used, a systematic evaluation comparison their performance using empirical genome-scale has so far lacking. To address this question, we evaluated four...
Olfactory-driven behaviors are central to the lifecycle of malaria vector mosquito Anopheles gambiae and initiated by peripheral signaling in antenna other olfactory tissues. To continue gaining insight into relationship between gene expression olfaction, we have performed cohort comparisons antennal transcript abundances at five time points after a blood meal, key event both reproduction disease transmission cycles. We found that more than 5,000 transcripts displayed significant abundance...
Cell-cycle checkpoints and DNA repair processes protect organisms from potentially lethal mutational damage. Compared to other budding yeasts in the subphylum Saccharomycotina, we noticed that a lineage genus Hanseniaspora exhibited very high evolutionary rates, low Guanine–Cytosine (GC) content, small genome sizes, lower gene numbers. To better understand evolution, analyzed 25 genomes, including 11 newly sequenced, representing 18/21 known species genus. Our phylogenomic analyses identify...
Eusocial insects use cuticular hydrocarbons as components of pheromones that mediate social behaviours, such caste and nestmate recognition, regulation reproduction. In ants Harpegnathos saltator, the queen produces a pheromone which suppresses development workers' ovaries if she is removed, workers can transition to reproductive state known gamergate. Here we functionally characterize subfamily odorant receptors (Ors) with nine-exon gene structure have undergone massive expansion in other...
The 1107 genomes yield a robust phylogenomic timetree and reveal contrasting modes of evolution in the largest fungal phylum.
Abstract Background Two sibling members of the Anopheles gambiae species complex display notable differences in female blood meal preferences. An. s.s. has a well-documented preference for feeding upon human hosts, whereas quadriannulatus feeds on vertebrate/mammalian with only opportunistic humans. Because mosquito host-seeking behaviors are largely driven by sensory modality olfaction, we hypothesized that hallmarks these divergent host seeking phenotypes will be evidence within...
Significance Evolutionary and comparative genomics, combined with reverse genetics, have the power to identify characterize new biology. Here, we use these approaches in several nontraditional model species of budding yeasts a yeast secondary metabolite gene cluster, set genes responsible for production reutilization siderophore pulcherrimin. We also this information assign roles pulcherrimin utilization two previously uncharacterized Saccharomyces cerevisiae genes. The evolution cluster...
The genetic code used in nuclear genes is almost universal, but here we report that it changed three times parallel during the evolution of budding yeasts. All changes were reassignments codon CUG, which translated as serine (in 2 yeast clades), alanine (1 clade), or 'universal' leucine (2 clades). newly discovered Ser2 clade final stages a transition. Most species this have for both novel tRNASer(CAG) and an ancestral tRNALeu(CAG) to read only standard growth conditions. coexistence these...
The relationships among the four major embryophyte lineages (mosses, liverworts, hornworts, vascular plants) and timing of origin land plants are enigmatic problems in plant evolution. Here, we resolve monophyly bryophytes by improving taxon sampling hornworts eliminating effect synonymous substitutions. We then estimate divergence time crown embryophytes based on three fossil calibration strategies, reveal that maximum constraints have a estimating plants. Moreover, comparison priors...
Angiosperms (flowering plants) are the most diverse and species-rich group of plants. The vast majority (∼99.95%) angiosperms form a clade called Mesangiospermae, which is subdivided into five major groups: eudicots, monocots, magnoliids, Chloranthales, Ceratophyllales. relationships among these Mesangiospermae groups have been subject long debate. In this study, we assembled phylogenomic dataset 1594 genes from 151 angiosperm taxa, including representatives all lineages, to investigate...
In most organisms, reproduction is correlated with shorter life span. However, the reproductive queen in eusocial insects exhibits a much longer span than that of workers.