A5100649070- Acne and Rosacea Treatments and Effects
- Dermatology and Skin Diseases
- Traditional Chinese Medicine Studies
- Endoplasmic Reticulum Stress and Disease
- Pancreatic function and diabetes
- Pharmacological Effects of Natural Compounds
- Coronary Interventions and Diagnostics
- Cleft Lip and Palate Research
- Adipose Tissue and Metabolism
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Metabolism, Diabetes, and Cancer
- Nail Diseases and Treatments
- Pregnancy and preeclampsia studies
- Translation Studies and Practices
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Inflammatory mediators and NSAID effects
- Ion channel regulation and function
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Heart Disease Studies
- melanin and skin pigmentation
- Sirtuins and Resveratrol in Medicine
Heze Municipal Hospital
2025
Wenzhou Medical University
2024
Wake Forest University
2015-2024
Hunan University of Science and Technology
2011-2024
Zhongnan University of Economics and Law
2024
Second Affiliated Hospital of Chengdu University of Traditional Chinese
2020-2023
Sichuan University
2014-2023
Sichuan Cancer Hospital
2018-2023
University of Electronic Science and Technology of China
2014-2023
Soochow University
2021-2023
Pressure overload-induced hypertrophy is a key step leading to heart failure. The Ca(2+)-induced Ca(2+) release (CICR) process that governs cardiac contractility defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive. To examine intermolecular aspects of CICR during hypertrophy, we utilized loose-patch confocal imaging visualize signaling between single L-type channel (LCC) and ryanodine receptors (RyRs) aortic stenosis rat models compensated (CHT) decompensated...
Endoplasmic reticulum (ER) stress induced apoptosis plays a pivotal role in myocardial ischemia/reperfusion (I/R)-injury. Inhibiting ER is major therapeutic target/strategy treating cardiovascular diseases. Our previous studies revealed that lycopene exhibits great pharmacological potential protecting against the I/R-injury vitro and vivo, but whether attenuation of (and) or stress-induced contributes to effects remains unclear. In present study, using neonatal mouse cardiomyocytes establish...
COVID-19 struck the world suddenly and unexpectedly. Since traditional education requires face-to-face communication, to avoid further spreading of virus a majority part that has moved online. Our study attempts compare differences between online medical with unique course design education. We conducted retrospective analysis total 4,098 students 2019 2020, including two groups who received classroom for same subjects, respectively. Freshmen enrolled in September 2018 physiology pharmacology...
<title>Abstract</title> Lung cancer is a primary malignant tumor of the lung that poses greatest health risk to population. An immune-associated protein family gene called T-cell immunoglobulin and mucin domain 1 (TIM-1) can be utilized as an immunological marker help diagnose cancer. However, correlation between TIM-1 polymorphisms has not been reported, so present study focused on genotyping polymorphic loci (rs1501909, rs2036402, rs2270924, rs870581) by TaqMan probe assay, aim was...
Autonomic dysfunction is a characteristic of cardiac disease and decreased vagal activity observed in heart failure. Rodent cardiomyocytes produce de novo ACh, which critical maintaining homeostasis. We report that this nonneuronal cholinergic system also found human cardiomyocytes, expressed choline acetyltransferase (ChAT) the vesicular acetylcholine transporter (VAChT). Furthermore, VAChT expression was increased 3- 1.5-fold at mRNA protein level, respectively, ventricular tissue from...
Abstract Aims and objectives To assess the level of stress response, self‐efficacy perceived social support status working nurses during outbreak COVID‐19 investigate potential factors affecting their stress. Background The clinical directly affects physical mental health work efficiency. Design This study was a cross‐sectional investigation, which performed following STROBE checklist. current conducted in February 2020 by selecting from Zigong First People's Hospital for investigation....
With Pennsylvania currently considering a move away from an Alcohol Beverage Control state to privatized alcohol distribution system, this study uses spatial analytical approach examine potential impacts of privatization on the number and outlets in city Philadelphia over long time horizon.A suite geospatial data were acquired for Philadelphia, including 1,964 outlet locations, 569,928 land parcels, school, church, hospital, park playground locations. These used as inputs exploratory...
Ethnicity is considered to be one of the major risk factors in certain subtypes breast cancer. However, mechanism this racial disparity remains poorly understood. Here, we demonstrate that SOS1, a key regulator Ras pathway, highly expressed African-American (AA) patients with cancer compared Caucasian-American patients. Because higher obesity rate AA women, increased levels SOS1 facilitated signal transduction c-Met which was activated via hepatocyte growth factor secreted from adipocytes....
Acyl‐CoA dehydrogenases (CADs) participate in mitochondrial fatty acid oxidation; abnormal oxidation is associated with obesity and related metabolic disorders. We decipher the impact of short‐chain CAD (SCAD) on adiposity insulin resistance. BALB/cBy strain mice derived from BALB/c are deficient SCAD activity because a spontaneous deletion acyl‐CoA ( Acads ) gene. Adiposity, lipogenesis, sensitivity were compared subjected to high‐fat diets (HFDs). A whole hepatic transcriptome profiling...