- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Sports Performance and Training
- Cancer survivorship and care
- Cardiovascular and exercise physiology
- Muscle Physiology and Disorders
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Diet, Metabolism, and Disease
- Obesity, Physical Activity, Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Vitamin C and Antioxidants Research
- Pharmacology and Obesity Treatment
- Body Composition Measurement Techniques
- Cancer Treatment and Pharmacology
- Mitochondrial Function and Pathology
- Radiation Therapy and Dosimetry
- Frailty in Older Adults
- Spaceflight effects on biology
- Biochemical effects in animals
- Protein Hydrolysis and Bioactive Peptides
- Cardiac Health and Mental Health
Maastricht University
2009-2024
TiFN
2022-2024
University Medical Center
2021-2024
Maastricht University Medical Centre
2009-2023
Northumbria University
2016
Newcastle University
2016
Committee on Publication Ethics
2015
McMaster University
2015
University of Bath
2011
Hartcentrum Hasselt
2008
Introduction The role of nutrition in modulating postexercise overnight recovery remains to be elucidated. We assessed the effect protein ingestion immediately before sleep on digestion and absorption kinetics metabolism during from a single bout resistance-type exercise. Methods Sixteen healthy young males performed exercise evening (2000 h) after full day dietary standardization. All subjects were provided with appropriate (20 g protein, 60 CHO) (2100 h). Thereafter, 30 min (2330 h),...
Exercise represents an effective interventional strategy to improve glycaemic control in type 2 diabetes patients. However, the impact of exercise intensity on benefits training remains be established. In present study, we compared clinical 6 months continuous low- moderate-intensity with those moderate- high-intensity training, matched for energy expenditure, obese patients.Fifty male patients (age 59 +/- 8 years, BMI 32 4 kg/m(2)) participated a month endurance-type programme. All...
It has been reported previously that mouth rinsing with a carbohydrate-containing solution can improve cycling performance. The purpose of the current study was to investigate impact such carbohydrate rinse on exercise performance during simulated time trial in more practical, postprandial setting. Fourteen male endurance-trained athletes were selected perform 2 tests morning after consuming standardized breakfast. They performed an ~1-hr cycle ergometer while their mouths either 6.4%...
The present study was designed to assess the impact of coingestion various amounts carbohydrate combined with an ample amount protein intake on postexercise muscle synthesis rates. Ten healthy, fit men (20 +/- 0.3 yr) were randomly assigned three crossover experiments. After 60 min resistance exercise, subjects consumed g x kg(-1) h(-1) hydrolysate 0, 0.15, or 0.6 during a 6-h recovery period (PRO, PRO + LCHO, and HCHO, respectively). Primed, continuous infusions...
Elevated plasma free fatty acid (FFA), inflammatory marker, and altered adipokine concentrations have been observed in obese type 2 diabetes patients. It remains unclear whether these are related to the diabetic state or presence of obesity. In this cross-sectional observational study, we compare basal FFA, between non-obese patients healthy, controls. A total 20 normoglycemic males (BMI <30 kg/m2), kg/m2) >35 were selected participate study. Groups matched for age habitual physical activity...
To investigate the relationship between skeletal muscle fiber type-specific characteristics, circulating hormone concentrations, and mass strength in older men.Cross-sectional analyses.University research center.Forty-one community dwelling elderly men (≥ 65).Leg (1-repetition maximum, 1RM) whole-body limb were determined, type composition, cross-sectional area (CSA), myonuclear content, satellite cell (SC) content assessed biopsy samples. In addition, blood samples collected to determine...
Leucine has been suggested to have the potential modulate muscle protein metabolism by increasing synthesis. The objective of this study was investigate surplus value co-ingestion free leucine with hydrolysate and carbohydrate following physical activity in elderly men. Eight men (mean age 73 ± 1 years) were randomly assigned two cross-over treatments consuming either (CHO+PRO) or carbohydrate, additional (CHO+PRO+leu) after performing 30 min standardized activity. Primed, continuous...
Introduction Both sarcopenia and spinal cord injury (SCI) are characterized by the loss of skeletal muscle mass function. Despite obvious similarities in atrophy between both models, differences fiber size satellite cell content may exist on a type–specific level. Methods In present study, we compared characteristics wheelchair-dependent young males with SCI (n = 8, 32 ± 4 yr), healthy elderly 75 2 controls 31 3 yr). Muscle biopsies were collected to determine type composition, size,...
In contrast to the effect of nutritional intervention on postexercise muscle protein synthesis, little is known about potential modulate synthesis during exercise. This study investigates coingestion with carbohydrate resistance-type Ten healthy males were studied in evening after they consumed a standardized diet throughout day. Subjects participated two experiments which ingested either or 2-h resistance exercise session. received bolus test drink before and every 15 min exercise,...
Purpose: We examined the impact of an acute bout resistance-type exercise on mixed muscle protein synthesis in fed state. Methods: After a standardized breakfast, 10 untrained males completed single, unilateral lower-limb session. A primed, continuous infusion l-[ring-13C6]phenylalanine was combined with biopsy collection from both exercised (Ex) and nonexercised (NEx) leg to assess local contractions rates after food intake. Western blotting phosphospecific pan antibodies used determine...
Skeletal muscle satellite cell (SC) content has been reported to increase following a single bout of exercise. Data on fibre type-specific SC and/or activation status are presently lacking. The objective the study was determine impact exercise and subsequent overnight recovery. Eight healthy men (age, 20 ± 1 years) performed combined endurance- resistance-type Muscle biopsies were collected before immediately after exercise, 9 h postexercise, myonuclear determined by immunohistochemical...
The purpose of this study was to assess the effects sucrose vs. glucose ingestion on postexercise liver and muscle glycogen repletion. Fifteen well-trained male cyclists completed two test days. Each day started with glycogen-depleting exercise, followed by 5 h recovery, during which subjects ingested 1.5 g·kg(-1)·h(-1) or glucose. Blood sampled frequently (13)C magnetic resonance spectroscopy imaging were employed 0, 120, 300 min determine concentrations volume. Results as follows:...
This study investigates the impact of protein coingestion with carbohydrate on muscle synthesis during endurance type exercise. Twelve healthy male cyclists were studied 2 h fasted rest followed by continuous cycling at 55% W max . During exercise, subjects received either 1.0 g·kg −1 ·h (CHO) or 0.8 0.2 hydrolysate (CHO+PRO). Continuous intravenous infusions l-[ ring- 13 C 6 ]phenylalanine and H ]tyrosine applied, blood biopsies collected to assess whole body turnover rates exercise...
Peak exogenous carbohydrate oxidation rates typically reach ~1 g∙min−1 during exercise when ample glucose or polymers are ingested. Fructose co‐ingestion has been shown to further increase rates. The purpose of this study was assess the impact fructose provided either as a monosaccharide part disaccharide sucrose on prolonged in trained cyclists. Ten male cyclists (VO2peak: 65 ± 2 mL∙kg−1∙min−1) cycled four different occasions for 180 min at 50% Wmax which they consumed solution providing...
This study aimed to assess the effects of 20 wk resistance exercise training with or without protein supplementation on body composition, muscle mass, strength, physical performance, and aerobic capacity in prostate cancer patients receiving androgen deprivation therapy (ADT).Sixty ADT were randomly assigned perform 31 g whey (EX + PRO, n = 30) placebo PLA, 30), consumed immediately after every night before sleep. A separate control group (CON, 36) only received usual care. At baseline wk,...
During exercise, the production of reactive oxygen and nitrogen species significantly increases. The aim present study was to investigate effects a single session resistance exercise on antioxidant capacity, oxidative damage, inflammation.Muscle biopsies, urine, blood samples were collected from seven healthy men before after bout exercise.A found induce as shown by 40% increase in concentration urinary F2alpha-isoprostanes (P < 0.05). Total capacity plasma increased 16% This seemed be...
Micellar casein is characterized as a slowly digestible protein source, and its structure can be modulated by various food processing techniques to modify functional properties. However, little known about the impact of such modifications on digestion amino acid absorption kinetics subsequent post-prandial plasma responses. In present study, we determined aminoacidemia following ingestion isonitrogenous amounts (40 g) provided micellar (Mi-CAS), calcium caseinate (Ca-CAS), or cross-linked...
To evaluate the criterion validity and responsiveness of steep ramp test (SRT) compared with cardiopulmonary exercise (CPET) in evaluating aerobic capacity survivors cancer participating a rehabilitation program.A prospective cohort study which performed an SRT CPET before (T=0) after (T=1) 10-week program. Peak work rate achieved during (SRT-WRpeak) was peak oxygen consumption measured (CPET-Vo2peak), is standard for capacity. Correlation coefficients were calculated between SRT-WRpeak...
Both protein and caffeine coingestion with CHO have been suggested to represent effective dietary strategies further accelerate postexercise muscle glycogen synthesis in athletes.This study aimed assess the effect of or on rates when optimal amounts are ingested.Fourteen male cyclists were studied three different test days. Each day started a glycogen-depleting exercise session. This was followed by 6-h recovery period, during which subjects received 1.2 g·kg⁻¹·h⁻¹ CHO, same amount 0.3 plus...