A5085204606- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Gastrointestinal disorders and treatments
- Atrial Fibrillation Management and Outcomes
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Liver Disease Diagnosis and Treatment
- Diverticular Disease and Complications
- Infant Health and Development
- Cardiac Arrhythmias and Treatments
- Microscopic Colitis
- Abdominal vascular conditions and treatments
- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Peptidase Inhibition and Analysis
- Therapeutic Uses of Natural Elements
- Congenital gastrointestinal and neural anomalies
- Diet and metabolism studies
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Bowel Disease
- Dysphagia Assessment and Management
University of Gothenburg
2021-2025
Sahlgrenska University Hospital
2019-2024
National University Hospital of Iceland
2013-2019
University of Iceland
2013-2018
Reykjavík University
2017
Objectives To investigate the incidence and outcomes of acute lower gastrointestinal bleeding (ALGIB) in a population-based setting examine role drugs potentially associated with GIB. Methods The study was prospective population based. cohort included all patients who underwent colonoscopy during year 2010 at National University Hospital Iceland. Indications for endoscopies drug history were recorded systematic manner. inclusion criteria overt leading to hospitalization or occurring...
Objective. The authors aimed to investigate the incidence and outcomes of acute upper gastrointestinal bleeding (AUGIB) examine role drugs potentially associated with AUGIB. Methods. study was prospective, population-based consisted all patients who underwent endoscopy (UGE), during year 2010 at National University Hospital Iceland. Drug intake NSAIDs, low-dose aspirin (LDA), warfarin, SSRIs bisphosphonates prior GIB prospectively registered also checked in a Pharmaceutical Database covering...
Gastrointestinal bleeding (GIB) rates for direct oral anticoagulants (DOACs) and warfarin have been extensively compared. However, population-based studies comparing GIB among different DOACs are limited.To compare of apixaban, dabigatran, rivaroxaban.Nationwide cohort study.Landspítali-The National University Hospital Iceland the 4 regional hospitals in Iceland.New users rivaroxaban from 2014 to 2019.Rates were compared using inverse probability weighting, Kaplan-Meier survival estimates,...
ABSTRACT Background Disorders of gut–brain interaction (DGBI) predominate in women, but little is known about sex differences menses‐related or menopause symptoms. Methods Using data from the Rome Foundation Global Epidemiology Survey, we assessed IV DGBI symptoms individuals 26 countries who met criteria for ≥ 1 5 DGBI: irritable bowel syndrome (IBS), functional dyspepsia (FD), constipation (FC), diarrhea (FDr), bloating (FB). Participants included pre‐ and post‐menopausal women with...
Abstract Background and Aims The Rome Foundation Global Epidemiology Study (RFGES) assessed the prevalence, burden, associated factors of Disorders Gut–Brain Interaction (DGBI) in 33 countries around world. Achieving worldwide sampling necessitated use two different surveying methods: In‐person household interviews (9 countries) Internet surveys (26 countries). Two countries, China Turkey, were surveyed with both methods. This paper examines differences survey results methods, as well likely...
The Rome criteria are widely accepted for diagnosing disorders of gut-brain interaction, but their global applicability has been debated. This study aimed to evaluate the validity IV by factor analysis globally, across geographical regions, sex, and age groups.Data were collected in 26 countries using questionnaire. Forty-nine ordinal variables used exploratory (EFA) identify clusters inter-correlated (factors) within data set. Confirmatory with predefined factors interaction was compared...
INTRODUCTION: This study focused on defining the global prevalence of clinically relevant levels psychological distress and somatic symptoms coexistence between these disorders gut-brain interaction (DGBI). We also analyzed how coexistent DGBI are associated with health-related outcomes. METHODS: included a representative sample 54,127 adult participants (49.1% women; mean age 44.3 years) from 26 countries worldwide. Participants completed an Internet survey (the Rome Foundation Global...
Purpose: There is a need for diagnostic and prognostic biosignatures to improve long-term outcomes in inflammatory bowel disease (IBD). Here, we describe the establishment of Swedish inception cohort IBD (SIC-IBD) demonstrate its potential identification such signatures. Participants: Patients aged 18 years or older with gastrointestinal symptoms who were referred gastroenterology unit due suspected at eight hospitals between November 2011 March 2021 eligible inclusion. Findings date: In...
Background: Perianal diseases are more common in patients with Crohn's disease (CD) than the general population, but data scarce other inflammatory bowel (IBD) subtypes.
ABSTRACT Background and Study Aims Probe‐based confocal laser endomicroscopy (pCLE) enables real‐time microscopic visualization of the duodenal mucosa has shown acute food–triggered disruption epithelial barrier patients with irritable bowel syndrome (IBS). The interpretation recordings is subjective, unknown agreement rates. aim this study was to investigate intra‐ interobserver variability technique. Patients Methods An international multicenter performed, including pCLE from three...
Abstract Background Irritable bowel syndrome (IBS) is highly prevalent worldwide but mechanisms for healthcare seeking behaviours in this patient group are poorly understood. Objective To describe utilization and identify factors associated with amongst IBS subjects the general population. Methods An internet survey was completed by 6,300 individuals equally distributed between United States, Kingdom Canada. The Rome IV diagnostic questionnaire used to IBS. Data on demographics, medical...
Objective: To determine the frequency of cytomegalovirus (CMV) and Epstein–Barr virus (EBV) hepatitis among those with acute CMV EBV infection in a population based setting to compare these two types analyze outcomes.Methods: A retrospective search was undertaken on all patients IgM antibodies during period 2006–2015 virological database University Hospital Iceland covering metropolitan area Reykjavík (population 202,255). Patients available liver tests at and/or admitted this institution...
Abstract Background Patients with disorders of gut-brain interaction (DGBI) report meal intake to be associated symptoms. DGBI patients meal-related symptoms may have more severe overall and worse health outcomes, but this subgroup has not been well characterized. We aimed describe the global prevalence abdominal pain characterize subgroup. Methods The data analyzed originated from Internet survey component population-based Rome Foundation Global Epidemiology Study, completed in 26 countries...
Abstract Background Disorders of Gut‐Brain Interaction (DGBI) are highly prevalent worldwide, but their effect on work productivity has not gained much attention. Aims and Methods We aimed to compare activity impairment (WPAI) in persons with without DGBI a large population‐based cohort identify factors independently associated WPAI subjects DGBI. Data were collected from Germany, Israel, Italy, Japan, the Netherlands, Poland, Spain Sweden via Internet surveys as part Rome Foundation Global...
Abstract Background Patients with organic gastrointestinal (GI) diseases and diabetes mellitus (DM) can have concomitant disorders of gut‐brain interaction (DGBI). Objective This study aimed to compare the global prevalence DGBI‐compatible symptom profiles in adults without self‐reported GI or DM. Methods Data were collected a population‐based internet survey 26 countries, Rome Foundation Global Epidemiology Study ( n = 54,127). Individuals asked if they had been diagnosed by doctor...
Population-based studies on patients with ischemic colitis (IC) are limited. We aimed to determine the incidence, risk factors and outcome of IC.A retrospective nationwide study was conducted adult histologically confirmed IC in 2009-2013 Iceland. were matched for age gender hospitalized lower gastrointestinal bleeding. Data collected clinical presentation, comorbidities, smoking habits, management outcome.Eighty-nine patients, 61 (69%) females mean 65 years (±17), fulfilled predetermined...
Abstract Background & aims Population‐based studies on the epidemiology of autoimmune hepatitis (AIH) are scarce. Drug‐induced AIH (DIAIH) is increasingly recognized in association with immunomodulatory therapy. We aimed to determine incidence, prevalence and natural history a population‐based setting. Methods collected data new diagnosis Iceland from 2006 2015. Cases were identified through search diagnostic codes text for within electronical medical records all hospitals smooth muscle...
Background Little is known about the major presenting features of patients with colorectal cancer (CRC) in a population-based setting, especially regarding bleeding-related symptoms. Aim To determine proportion CRC symptoms, to compare bleeders and nonbleeders explore role anticoagulants bleeders. Methods This was nationwide, population-based, retrospective study, investigating all diagnosed Iceland from 2008 2011. Bleeding-related symptoms were defined as overt bleeding, iron deficiency...
ABSTRACT Background Abdominal pain can be an overlooked symptom in patients with ulcerative colitis (UC). Aims The aim of this study was to investigate the prevalence and factors associated abdominal active quiescent UC. Methods Three cohorts adult UC were used. Cross‐sectional I II included 130 (46 active) 288 (156 patients. Longitudinal cohort III 83 disease at diagnosis that reached deep remission during follow‐up. Gastrointestinal Symptom Rating Scale used assess other validated...