A5101622824- Cancer-related molecular mechanisms research
- Ovarian function and disorders
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Sexual Differentiation and Disorders
- Hepatitis B Virus Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Immunotherapy and Immune Responses
- Medicinal Plant Pharmacodynamics Research
- Reproductive Biology and Fertility
- Endometriosis Research and Treatment
- Phytochemistry and Bioactive Compounds
- Lung Cancer Treatments and Mutations
- Crystallization and Solubility Studies
- 14-3-3 protein interactions
- Angiogenesis and VEGF in Cancer
- X-ray Diffraction in Crystallography
- Estrogen and related hormone effects
- Reproductive Health and Contraception
- Cancer Genomics and Diagnostics
- Phosphodiesterase function and regulation
- Hepatitis Viruses Studies and Epidemiology
Zhejiang Normal University
2015-2022
Jinhua Academy of Agricultural Sciences
2018-2021
Zhejiang University
2013
Aquaporin-1 (AQP1) has been proposed as a mediator of estrogen-induced angiogenesis in human breast cancer and endometrial cancer. Elucidation the molecular mechanisms governing AQP1-mediated, may contribute to an improved understanding tumor development.Our objective was identify estrogen-response element (ERE) promoter Aqp1 gene investigate effects AQP1 on tubulogenesis vascular endothelial cells.The study conducted university hospital eastern China.Immunohistological, real-time PCR...
Abstract Background Identification of master regulators (MRs) using transcriptome data in cervical cancer (CC) could help us to develop biomarkers and find novel drug targets fight this disease. Methods We performed differential expression (DE) analyses public microarray RNA-seq CC normal tissues (N). Virtual Inference Protein activity by Enriched Regulon analysis (VIPER) was used convert the DE outcomes (DA) signature for MRs. Synergy conducted study synergistic effect MR-pairs. TCGA were...
Background The long non-coding RNA (lncRNA) small nucleolar host gene 5 (SNHG5) has been verified as a crucial regulator in many types of tumours but not clear cervical cancer (CC). This study aims to investigate the effect and further mechanisms lncRNA SNHG5 CC.Methods expression miR-132, well SOX4 (sex-determining region Y-box 4) mRNA were determined by quantitative real-time PCR (qRT-PCR). protein level epithelial-mesenchymal transition (EMT)-related proteins evaluated western blot. Then,...
Introduction Polycystic ovary syndrome (PCOS) is one of the leading causes female infertility, affecting around 5% women childbearing age in China. Vitamin D insufficiency common with PCOS and associated lower live birth rates. However, evidence regarding effectiveness vitamin supplementation inconclusive. This multicentre randomised, double-blinded, placebo-controlled trial aims to evaluate prior vitro fertilisation (IVF) on rate PCOS. Methods analysis We plan enrol scheduled for IVF. After...
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of ovarian stimulation. Prevention and early recognition OHSS are important to ensure patient safety.In this case, we reported a who underwent controlled (COH) in vitro fertilization (IVF). All embryos were cryopreserved reduce possible OHSS. However, still occurred after the had frozen-thawed embryo transfer (FET) with hormone replacement therapy (HRT) obtained dichorionic diamniotic triplet pregnancy. After multifetal...
MicroRNA-320d (miR-320d) is a novel cancer-related miRNA and functions as tumor suppressor in human cancers.
Abstract Study question Is it safe using aspirin (A) and prednisone (P) before pregnancy among women with antithyroid antibodies (ATAbs) undergoing assisted reproductive technology? Summary answer Combination therapy of didn’t improve likelihood clinical pregnancy, but increased miscarriage rate. What is known already Compared negative-ATAb, positive-ATAb had a lower live birth rate higher Insufficient evidence existed to determine whether improved the success following technology (ART) in...