- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- MRI in cancer diagnosis
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis Viruses Studies and Epidemiology
- Radiomics and Machine Learning in Medical Imaging
- Advanced Radiotherapy Techniques
- Liver Disease and Transplantation
- Viral gastroenteritis research and epidemiology
- Oral microbiology and periodontitis research
- Glioma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Liver Diseases and Immunity
- Tracheal and airway disorders
- Chronic Kidney Disease and Diabetes
- Epigenetics and DNA Methylation
- Brain Metastases and Treatment
- Nerve Injury and Rehabilitation
- Congenital Diaphragmatic Hernia Studies
- Prostate Cancer Treatment and Research
- Salivary Gland Disorders and Functions
- Advanced MRI Techniques and Applications
- Zoonotic diseases and public health
Shenzhen Center for Disease Control and Prevention
2024
Zhongda Hospital Southeast University
2018-2023
Nanjing Drum Tower Hospital
2023
Nantong University
2018-2021
Second People's Hospital of NanTong
2018-2021
Affiliated Hospital of Nantong University
2020
Liaocheng People's Hospital
2019
Beijing Jishuitan Hospital
2010
Peking University
2010
Qidong Liver Cancer Prevention Research
2006
We aimed to investigate the efficacy and safety of telbivudine (LdT) on intervention mother-to-child transmission (MTCT) in different trimesters pregnant women with high viral loads.In this prospective cohort study, 160 cases mothers loads were included. Eighty-two subjects received 600 mg/day LdT therapy. Fifty them started therapy before third trimester gestation, including 17 pregnancy, nine 24 first second respectively. The other 32 gestation. Control (78 cases) did not take MTCT rate...
Albuminuria and podocyte injury are the key cellular events in progression of diabetic nephropathy (DN). Acetyl-CoA synthetase 2 (ACSS2) is a nucleocytosolic enzyme responsible for regulation metabolic homeostasis mammalian cells. This study aimed to investigate possible roles ACSS2 kidney DN. We constructed an ACSS2-deleted mouse model role dysfunction models. In vitro, podocytes were chosen transfected with siRNA inhibitor treated high glucose. found that expression was significantly...
Objective To explore the correlations of radiomic features dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with microvessel density (MVD) in patients hepatocellular carcinoma (HCC), based on single-input and dual-input two-compartment extended Tofts (SITET DITET) models. Methods We compared quantitative parameters SITET DITET models for DCE-MRI 30 HCC using paired sample t-tests. The model CD31-MVD CD34-MVD were analyzed Pearson’s correlation analysis. A diagnostic was...
To investigate the feasibility and safety of computed tomography-magnetic resonance imaging (CT-MRI) fusion-guided iodine-125 seed implantation for a single malignant brain tumor.From November 2015 to October 2016, 12 patients with tumor were treated permanent seeds implantation. CT-MRI fusion images used make preoperative treatment plan, intraoperative dose optimization, postoperative verification, response follow-up. The dosimetry parameters image plans compared between preprocedures...
The present study evaluated three-dimensional proton magnetic resonance spectroscopy (MRS) and diffusion-weighted imaging (DWI) features in differentiating incidental prostate carcinoma (IPCa) benign hyperplasia (BPH) the central gland of prostate. clinical data 9 patients with IPCa, 118 BPH [including those glandular (GH), stromal (SH) mixed (MH)], were retrospectively analyzed. mean (choline + creatine)/citrate (CC/C) value 3D MRS, apparent diffusion coefficient (ADC) minimal ADC DWI...
From June 16 to 30, 2023, men who have sex with (MSM) had visited Voluntary Counseling Testing (VCT) clinics in the Luohu, Futian and Nanshan districts of Shenzhen were included this study analyze their awareness Mpox influencing factors. The mean age 262 MSM was (34.78±8.94) years, majority being unmarried (75.2%) 79.0% confirmed be infected HIV. rates for five primary indicators, current status Mpox, pathogen source infection, mode transmission, population susceptibility, clinical...
Objective To investigate the effectiveness of T1 mapping on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA-enhanced) MRI for assessment liver function. Methods One hundred and twenty six patients with clinically suspected focal lesions chronic viral hepatitis B underwent were prospectively enrolled. Patients divided into four subgroups as follows: (n=22), cirrhosis Child-Pugh A (n=52), (n=41), C (n=11). Twenty three healthy volunteers normal function enrolled...
Objective To explore the effect of hyaluronic acid gel combined with periodontal therapy on gingival crevicular fluid tumor necrosis factor alpha (TNF-α) and soluble intercellular adhesion molecule -1 (sICM-1) in patients periodontitis. Methods 80 periodontitis treated our hospital from January, 2017 to 2019 were selected. According random number table method, divided into a control group (40 cases) an observation cases). The was basic treatment. basis indicators examination [PD,...
Objective To investigate the quantitative evaluation efficiency of gadolinium- ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced T1 mapping in staging hepatic fibrosis caused by viral hepatitis B. Methods One hundred and fifty patients with chronic B were prospectively enrolled Shanghai Public Health Clinical Center, Fudan University from August 2016 to 2018.These underwent liver aspiration biopsy divided into four subgroups: S1 (n=38), S2 (n=30), S3 (n=33), S4...