A5039201942- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- Drug-Induced Hepatotoxicity and Protection
- Silymarin and Mushroom Poisoning
- Neuroscience of respiration and sleep
- Liver Diseases and Immunity
- Eosinophilic Esophagitis
- COVID-19 Impact on Reproduction
- Viral Infections and Vectors
- Biomarkers in Disease Mechanisms
- Botulinum Toxin and Related Neurological Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Hepatitis C virus research
- Metabolism and Genetic Disorders
- Diabetes Management and Research
- Leptospirosis research and findings
- Neonatal Respiratory Health Research
- Cardiovascular Syncope and Autonomic Disorders
- Bacterial Infections and Vaccines
- Pediatric health and respiratory diseases
- Diagnosis and treatment of tuberculosis
- bioluminescence and chemiluminescence research
- Respiratory Support and Mechanisms
- Celiac Disease Research and Management
Ryazan State Medical University named after Academician I.P. Pavlov
2016-2024
Budgetary Healthcare Institution of Omsk Region Regional Clinical Hospital
2024
Botulism is a severe neuroparalytic disease caused by botulinum toxin (BoNT) produced vegetative forms of Clostridium or, in rare cases, other clostridium species. This review devoted to the problem iatrogenic botulism (iatB) and describes epidemiological, pathogenetic, clinical features iatB, which are important for physicians various specialties at current stage expanding indications therapy timely effective medical care persons with iatB manifestations. Key words: botulinum, neurotoxin,
Once a patient has been diagnosed with severe COVID-19 pneumonia, treatment options have limited effectiveness. Opaganib is an oral under investigation being evaluated for of hospitalized patients pneumonia. A randomized, placebo-controlled, double-blind phase 2/3 trial was conducted in 57 sites worldwide from August 2020 to July 2021. Patients received either opaganib (n = 230; 500 mg twice daily) or matching placebo 233) 14 days. The primary outcome the proportion no longer requiring...
Potentiation of chronic inflammation and oxidative stress by a new infectious agent in patients with type 2 diabetes mellitus can cause severe course the disease. However, study manifestations hyperglycemia diseases is not widespread. This review reveals features state antioxidant system devoted to identifying possible biochemical markers that predict infections among such patients.
Relevance. In patients with acute viral hepatitis A and B, favorable conditions are created for the development of dysbacteriosis. As a result, toxic load on liver increases. For effective treatment it is necessary to examine intestinal dysbiosis before after subsequent correction identified disorders. Aim. To study clinical course, functional state liver, microflora in B effectiveness using bifidumbacterin forte microflora. Materials methods. The work used laboratory data from 54 B. main...
The article contains a description of generalized sarcoidosis diagnosed morphologically after cholecystectomy for phlegmonous cholecystitis.
Relevance. In patients with acute viral hepatitis A and B, favorable conditions are created for the development of dysbiotic changes. As a result, toxic load on liver increases. For effective treatment combined administration probiotics hepatoprotectors is necessary. Aim. To study clinical course, functional state liver, intestinal microflora in effectasy using combination to correct microflora. Materials methods. The work used laboratory data 74 AVHA AVHB. main group received complex...
Aim. To identify the features of course COVID-19 in patients with type 2 diabetes mellitus (T2DM), depending on intake hypoglycemic therapy at prehospital stage, conjunction functional state kidneys.Materials and methods. A retrospective analysis 291 case histories T2DM hospitalized infection department Semashko Regional Clinical Hospital from January to December 2021, including main clinical laboratory parameters.Results. Among COVID-19, had a higher mortality rate. An deceased showed that...
The coronavirus infection (COVID-19) is quite effectively contained by vaccination campaigns. However, in a number of patients, despite history vaccination, COVID-19 develops, requiring hospitalization and ending death. Objectives. To study the differences mortality course new among patients hospitalized hospitals city Ryazan (Russian Federation) Semey Pavlodar (Republic Kazakhstan). We determined with without vaccine status according to anamnestic data. And also compared need for invasive...
The article shows the results of endoscopic and morphological studies pathology upper gastrointestinal tract (GIT) in 174 patients both sexes with hemorrhagic fever renal syndrome (HFRS), leptospirosis tularemia. high frequency erosive ulcerative changes mucosa due to deep microcirculatory disorders. We found that interrelated leading clinical laboratory parameters, severity time occurrence underlying disease. considered variants connection abdominal syndrome. study showed associating...
Introduction. Patients with acute viral hepatitis B (AVHB) during the peak may develop erosions and ulcers of mucous membrane upper gastrointestinal tract, which are difficult to diagnose clinically. Aim. The differences in clinical laboratory manifestations B, depending on presence or absence erosive ulcerative defects tract has studied. Materials methods. work used data results endoscopic examination 44 patients AVHB. All underwent a comprehensive examination, supplemented by...
The article presents the results of studies aimed at studying effect a metabiotic drug on biochemical parameters blood calves. As result feeding calves dairy period growing dose 20 ml/ head, an increase in serum content albumins by 3,7 % (p ≤ 0,001), ASaT 3,3 0,05), ALaT 38,2 0,001) was noted.