A5091471983- Virus-based gene therapy research
- Animal Virus Infections Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Herpesvirus Infections and Treatments
- Animal Nutrition and Physiology
- Immune Response and Inflammation
- Salmonella and Campylobacter epidemiology
- Aquaculture disease management and microbiota
- Immune cells in cancer
- Cytomegalovirus and herpesvirus research
- Antibiotic Resistance in Bacteria
- Sperm and Testicular Function
- Milk Quality and Mastitis in Dairy Cows
- Probiotics and Fermented Foods
- Viral gastroenteritis research and epidemiology
- Reproductive Biology and Fertility
- Antimicrobial Peptides and Activities
- TGF-β signaling in diseases
- Animal Disease Management and Epidemiology
- Chronic Kidney Disease and Diabetes
- Parvovirus B19 Infection Studies
- Molecular Biology Techniques and Applications
- Cancer-related molecular mechanisms research
- Microbial infections and disease research
- Biological Stains and Phytochemicals
Chiang Mai University
2016-2025
Iowa State University
2008-2011
Introduction Asian elephants ( Elephas maximus ) provide a unique model for studying cloning in large mammals. As an endangered species with declining populations and limited oocyte availability, interspecies somatic cell nuclear transfer (iSCNT) combined transcriptomic analysis holds promise advancing iSCNT embryonic arrest development further facilitating applications conservation efforts, therapeutic cloning, regenerative medicine. Methods This study conducted low-input RNA sequencing...
Chronic kidney disease (CKD) is prevalent among older cats. The transforming growth factor beta 1 (TGF-β1) pathway associated with renal fibrosis. TGF-β1 signaling through the non-canonical/smad-independent activates mitogen-activated protein kinase (MAPK) signaling, which linked to fibrosis and apoptosis. MAPK regulates Bcl-2 family, known for its anti-apoptosis properties. This study aimed quantify mRNA expression of TGFβ, MAPK, Bcl2 genes in feline cells tissue. A gene analysis was...
Heterophils, the avian polymorphonuclear leukocyte and counterpart of mammalian neutrophils, generate primary innate response to pathogens in chickens. Heterophil performance against is associated with host disease resistance, heterophil gene expression function are under genetic control. To characterize genomic basis function, heterophils from F(13) advanced intercross chicken lines (broiler × Leghorn broiler Fayoumi) were assayed for phagocytosis killing Salmonella enteritidis, oxidative...
Traditionally, non-aureus staphylococci and mammaliicocci (NASM) were not considered significant players in bovine mastitis. This study investigated the involvement of NASM (Staphylococcus hominis Staphylococcus chromogenes) lactic acid bacteria (LAB) strains (Weissella paramesenteroides) through neutrophil responses. Bovine neutrophils displayed minimal apoptosis upon LAB challenge. Neutrophils expressed high TLR2 after challenge, but TLR6 expression varied remained low pathogen...
Aim: To investigate gene expression of microRNA (miRNA) milieus (MIRLET7E, MIR17, MIR24-2, MIR146A, and MIR181C), inflammatory cytokine genes (interleukin 1β [IL1B], IL6, CXCL8, tumor necrosis factor [TNF]), the pathogen receptor toll-like (TLR4) in bovine neutrophils under quercetin supplementation.Materials Methods: Isolated were incubated with bacterial lipopolysaccharide treatment or left untreated.Real-time polymerase chain reaction was performed to determine miRNAs messenger RNA (mRNA)...
Streptococcus uberis is frequently isolated from milk collected dairy cows with mastitis. According to the host’s immunity, bacterial virulence, and their interaction, infection some strains can induce persistent subclinical inflammation, while others induces severe inflammation transient This study compared inflammatory response of milk-isolated white blood cells (mWBCs) S . strains. Quarter samples were aseptically for culture all lactating once a week over 10-week period. A noncapsular...
Introduction. The northern region of Thailand serves as a crucial area for swine production, contributing to the Thai community food supply. Previous studies have highlighted presence foodborne bacterial pathogens originating from farms in this region, posing threat both human and animal health. Gap statement. Multiple been studied at species level, but distribution co-occurrence agricultural has not well established. Aim. Our study employed intestinal scraping technique directly examine...
Elephant endotheliotropic herpesvirus-hemorrhagic disease (EEHV-HD) is the primary cause of acute, highly fatal, hemorrhagic diseases in young Asian elephants. Although monocytopenia frequently observed EEHV-HD cases, role monocytes play EEHV-disease pathogenesis unknown. This study seeks to explain responses monocytes/macrophages EEHV-HD. Samples blood, frozen tissues, and formalin-fixed, paraffin-embedded (FFPE) tissues from EEHV1A-HD, EEHV4-HD, co-infected EEHV1A 4-HD, EEHV-negative...
Bovine mastitis caused by Staphylococcus aureus may exacerbate resulting in significant economic losses and impacting milk quality. To date, the use of gallic acid, a phenolic compound naturally occurring various plants, holds promise due to its potent anti-oxidant anti-inflammatory effects many pieces literature, thus, making it subject interest bovine innate immunity research. Here we used acid assess potential immunomodulation on phagocytes vitro challenges with mastitis-causing bacteria....
Bovine mastitis is primarily caused by a group of bacteria known as Staphylococcus and Streptococcus. However, additional types bacteria, such bovine non-aureus staphylococci mammaliicocci (NASM) well lactic acid (LAB), are considered minor pathogens have less impact on cows. Modulating neutrophil activities gene expressions in response to bacterial stimuli prompted the cells execute effector functions combat udder infections. Although neutrophils can manage major mastitis-causing this...
Vaccines, antibiotics, and other therapeutic agents used to combat disease in poultry generate recurring costs the potential of residues products. Enhancing immune response using alternative approaches such as selection for increased resistance or dietary immunomodulation may be effective additions portfolio strategies industry applies health management. The objective this study was characterize effects supplementation with 3 immunomodulators [ascorbic acid, 1,3-1,6 β-glucans from baker's...
Chicken heterophils generate reactive oxygen species (ROS) molecules to defend against invading pathogens. The present study examined effects of quercetin on chicken heterophils. Heterophils were stimulated with PBS, 50 µM (QH), PMA or Escherichia coli (EC) and the resulting intracellular ROS determined. Flow cytometry results showed that cells QH, EC had a higher production. Increases in identified all treatment groups by fluorescence microscopy. Determination ability manipulate mRNA...
The in vitro virustatic and virucidal tests of the crude extract Cynodon dactylon against infection with porcine reproductive respiratory syndrome virus (PRRSV), a cause major devastating pig disease, were described. Crude C. was prepared for cytotoxicity on tissue-culture cells that used to measure activities PRRSV. at 0.78 mg/mL showed no cell line, concentration significantly inhibited replication PRRSV as early 24 hours post (hpi). also inactivated determined by immunoperoxidase...
The use of metal oxide nanoparticles as an alternative antimicrobial agent has gained attention due to the increasing problem resistance. Understanding its properties and potential benefits can contribute development more effective sustainable treatments in veterinary medicine. aim this study was characterize TiO2-NP formulations evaluate their antibacterial wound healing abilities. diameters zeta potentials were determined using Zetasizer conjunction with dynamic light scattering. agar-well...
Abstract Human salmonellosis is a major public health problem worldwide. Infections can pass to humans by contact with contaminated substances in the food chain. This study aimed determine prevalence and contamination levels of Salmonella isolated from pork, chicken beef sold different types retail stores Chiang Mai Lamphun provinces investigate genetic relatedness among isolates chains that area. A total 360 meat samples supermarkets, mini‐grocery fresh markets were obtained. Rissen S....