A5045575661- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Trypanosoma species research and implications
- Streptococcal Infections and Treatments
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Infective Endocarditis Diagnosis and Management
- Pediatric health and respiratory diseases
- Genomics and Phylogenetic Studies
- Immunodeficiency and Autoimmune Disorders
- Parasites and Host Interactions
- Urinary Tract Infections Management
- Research on Leishmaniasis Studies
- Pediatric Urology and Nephrology Studies
- Bacteriophages and microbial interactions
- Cystic Fibrosis Research Advances
- Infections and bacterial resistance
- Nanoparticles: synthesis and applications
- Anatomy and Medical Technology
Hospital Universitari i Politècnic La Fe
2008-2024
Instituto de Investigación Sanitaria La Fe
2017-2023
Instituto Valenciano de la Edificación
2023
Leitat Technological Center
2011-2021
Universidad Nacional de Asunción
2019
Hospital Universitario Fundación Jiménez Díaz
2017
Andover Eye Associates
2014
Instituto Politécnico Nacional
2012
Czech Academy of Sciences, Institute of Microbiology
2007
Abstract Introduction Biofilm in endotracheal tubes (ETT) of ventilated patients has been suggested to play a role the development ventilator-associated pneumonia (VAP). Our purpose was analyze formation ETT biofilm and its implication response relapse VAP. Methods We performed prospective, observational study medical intensive care unit. Patients mechanically for more than 24 hours were consecutively included. obtained surveillance aspirates (ETA) twice weekly and, at extubation, ETTs...
The utility of procalcitonin levels to improve the accuracy clinical and microbiological parameters in diagnosing ventilator-associated pneumonia (VAP) was evaluated. Sequential measurement C-reactive protein calculation simplified Clinical Pulmonary Infection Scores (CPIS) were performed 44 patients mechanically-ventilated for >48 h with neither active infection duration or suspicion VAP. Patients who developed extrapulmonary excluded. In total, 20 cases suspected having VAP diagnosis...
ABSTRACT Escherichia coli and the antimicrobial pressure exerted on this microorganism can be modulated by factors dependent host. In paper, we describe distribution of resistance to amikacin, tobramycin, ampicillin, amoxicillin clavulanate, cefuroxime, cefoxitin, cefotaxime, imipenem, ciprofloxacin, fosfomycin, nitrofurantoin, trimetoprim-sulfametoxazole in more than 100,000 E. isolates according culture site patient age, gender, location. Bayesian inference was planned all statistical...
ABSTRACT Background and objective The of this study was to evaluate the effect age comorbidities, smoking alcohol use on microorganisms in patients with community‐acquired pneumonia ( CAP ). Methods A prospective multicentre performed 4304 patients. We compared microbiological results, bacterial aetiology, smoking, abuse comorbidities three groups: young adults (<45 years), (45–64 years) seniors (>65 years). Results Bacterial aetiology identified 1522 (35.4%) In seniors, liver disease...
Non-cystic fibrosis bronchiectasis is a chronic structural lung condition that courses with recurrent infectious exacerbations lead to frequent antibiotic treatment making this population more susceptible acquire pathogens resistance. We aimed investigate risk factors associated isolation of multidrug-resistant in exacerbations.A prospective observational study was conducted two tertiary-care hospitals, enrolling patients when first exacerbation appeared. Multidrug-resistance determined...
Chagas disease, a neglected tropical is now considered worldwide health concern as result of migratory movements from Central and South America to other regions that were free the where epidemiological risk limited transplacental transmission or blood organ donations infected persons. Parasite detection in chronically ill patients restricted serological tests only determine infection by previous not presence parasite, especially undergoing treatment evaluation newborns. We have evaluated use...
Abstract Urinary tract infections (UTIs) are among the most common bacterial and a frequent cause for hospitalization in elderly. The aim of our study was to analyse epidemiological, microbiological, therapeutic, prognostic elderly hospitalised patients with determine independent risk factors multidrug resistance its outcome implications. A single-centre observational prospective cohort analysis 163 adult hospitalized suspected symptomatic UTI Departments Internal Medicine, Infectious...
Fossil fuel derived pollutants (SO2, NO), dry air and cold increase the incidence of S. pneumoniae infections http://ow.ly/RnLW30gogb1.
Multiple observational studies suggest an increased risk of colon cancer in patients with diabetes mellitus (DM). This can theoretically be the result influence diabetic environment on carcinogenesis or tumor biologic behavior.To gain insight into a characteristics and outcomes.Retrospective analysis clinical records academic tertiary care hospital detailed 81 diagnosed matched 79 non-diabetic patients. The impact streptozotocin-induced growth xenografts was studied mice.The incidence DM...
Abstract Incidence of pneumococcal disease has increased worldwide in recent years. Response to vaccine is usually measured using the multiserotype enzyme-linked immunosorbent assay (ELISA) test. However, this approach presents several limitations. Therefore, introduction new and more robust analytical approaches able provide information on efficacy would be very beneficial for clinical management patients. Surface plasmon resonance (SPR) been shown offer a valuable understanding vaccines’...
Bronchiectasis is a common progressive respiratory disease characterized by exacerbations and recurrent chest infections with high morbidity reduced quality of life. Cole«SQ»s vicious cycle model explains the evolution this disease, in which an initial insult bronchi, often on background impaired mucociliary clearance or bactericidal activity, results persistence microbes sinobronchial tree microbial colonization. Microbial overgrowth then causes infection chronic inflammation, resulting...