- Venomous Animal Envenomation and Studies
- Plant tissue culture and regeneration
- Phytochemistry Medicinal Plant Applications
- Essential Oils and Antimicrobial Activity
- Bioactive Natural Diterpenoids Research
- Phytochemistry and Biological Activities
- Insect Pest Control Strategies
- Alkaloids: synthesis and pharmacology
- Allelopathy and phytotoxic interactions
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- Microplastics and Plastic Pollution
- Agricultural and Food Sciences
- Healthcare and Venom Research
- Biochemical and Structural Characterization
- Phytochemistry and Bioactivity Studies
- Toxin Mechanisms and Immunotoxins
- Medicinal Plants and Neuroprotection
- Weed Control and Herbicide Applications
- Phytochemistry and Bioactive Compounds
- Nanoparticles: synthesis and applications
- Marine Sponges and Natural Products
- Growth and nutrition in plants
- Nematode management and characterization studies
- Phytochemicals and Antioxidant Activities
Universidade de Ribeirão Preto
2007-2025
Universidade Federal de Goiás
2020-2024
Vale (Brazil)
2024
Instituto Federal Goiano
2016-2023
Instituto Federal de Educação, Ciência e Tecnologia do Pará
2023
Instituto Federal de Goiás
2018-2022
Universidade Estadual de Londrina
2018-2021
Institute of Science and Technology
2020
University of Guayaquil
2020
Universidade Federal de Mato Grosso
2020
Essential oils (EO) from aromatic and medicinal plants generally perform a diverse range of biological activities because they have several active constituents that work in different mechanisms action. EO Citrus peel an impressive food uses, besides other applications. reticulata, C. sinensis deliciosa were extracted fruit analyzed by GC-MS. The major constituent under evaluation was limonene, whose concentrations 98.54%, 91.65% 91.27% for sinensis, reticulata deliciosa, respectively....
Abstract: We genetically modified Eclipta alba using Agrobacterium rhizogenes LBA 9402, with the aim of producing secondary metabolites pharmacological properties against phospholipase A 2 and myotoxic activities snake venom. Extracts from in natura aerial parts roots, both native ( vitro ), were prepared analysed by high‐performance liquid chromatography. In materials showed coumestan wedelolactone at higher concentration parts, while demethylwedelolactone appeared roots. Among clone 19...
This work describes the isolation and structural determination of pharmacological compounds present in bark roots Tabernaemontana catharinensis (Apocynaceae). Among 27 substances detected 12 were identified as terpenoid-indole alkaloids, 2 steroids 13 pentacyclic triterpenes. Structures outlined based on HMQC, COSY, DEPT, 13C, ¹H NMR data MS. Spectral indole alkaloids reviewed. An vitro screening extracts isolated was carried out. Compounds ibogamine (5), 3-oxo-coronaridine (9)...
In Brazilian folk medicine, victims of bites by poisonous animals are usually treated with plant extracts derived from the diverse national flora. The chemical and pharmacological properties most were yet not investigated. rural community Assis-SP, root bark Tabernaemontana catharinensis ("leiteiro", "cow milk") is applied to site snake bite believed neutralize effect venom. We report here ability lyophilized aqueous extract (AE) a pure compound obtained ethanolic T. inhibit lethal myotoxic...
Abstract Lafoensia pacari St. Hil. (Lythraceae) is used in traditional medicine to treat inflammation. Previously, we demonstrated the anti-inflammatory effect that ethanolic extract of L. has Toxocara canis infection (a model systemic eosinophilia). In this study, tested antiinflammatory activity same mice injected intraperitoneally with β-glucan present fraction 1 (F1) Histoplasma capsulatum cell wall acute eosinophilic inflammation). We also determined anti-oedematous, analgesic and...
Ampelozizyphus amazonicus Ducke is a tree commonly found in the Amazon region and an extract of its stem bark popularly used as antimalarial anti-inflammatory agent antidote to snake venom. Ursolic acid; five lupane type triterpenes: betulin, betulinic acid, lupenone, 3beta-hydroxylup-20(29)-ene-27,28-dioic 2alpha,3beta-dihydroxylup-20(29)-ene-27,28-dioic three phytosteroids: stigmasterol, sitosterol campesterol, have been isolated from extracts A. Ducke. Their structures were characterized...
Four compounds (isoquercitrin, myricetin-3-O-glucoside, catechin and gallocatechin) were isolated from lyophilized aqueous extract of Schizolobium parahyba leaves by chromatography on Sephadex LH-20, followed semipreparative HPLC using a C-18 column, identified 1H 13C NMR. The then, tested against hemorrhagic fibrinogenolytic activities Bothrops crude venoms metalloproteinases. inhibitors neutralized the biological enzymatic toxins B. jararacussu neuwiedi venoms. results showed that...
This study aimed at determining, for the first time, chemical composition of essential oils from fresh leaves Citrus limonia and latifolia evaluating its in vitro antibacterial, trypanocidal, leishmanicidal cytotoxic effects.The C. were extracted by hydro distillation analyzed GC-MS.The oil yield was 0.8% 0.5% limonia, whereas 17 18 components identified respectively.Major limonene (46.3 %), nerol (10.0 %) 1,8-cineole (13.4 %).In antibacterial activity evaluated against bacteria...
Medicinal plants constitute a very rich source of natural inhibitors animal toxins, and may be used: 1) to study the mechanism action toxins inhibitors; 2) treat ophidian envenomation as supplementary and/or alternative therapy; 3) models design new drugs interest in clinical medicine. Several Brazilian have been utilized folk medicine antiophidians. However, only few species scientifically investigated still fewer had their active components isolated characterized both structurally...