- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cancer Cells and Metastasis
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Microfluidic and Bio-sensing Technologies
- Cardiac Structural Anomalies and Repair
- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiac tumors and thrombi
- Microfluidic and Capillary Electrophoresis Applications
- Cardiac pacing and defibrillation studies
- Neuroblastoma Research and Treatments
- Cancer Treatment and Pharmacology
- Amoebic Infections and Treatments
- Heart Failure Treatment and Management
- Pancreatitis Pathology and Treatment
- Abdominal Trauma and Injuries
- Gallbladder and Bile Duct Disorders
- Cardiovascular and Diving-Related Complications
- Pediatric Urology and Nephrology Studies
Kurashiki Central Hospital
2019-2025
Shizuoka Cancer Center
2012-2021
Mitsubishi Kyoto Hospital
2004
Background Epithelial cell adhesion molecule (EpCAM)-based enumeration of circulating tumor cells (CTC) has prognostic value in patients with solid tumors, such as advanced breast, colon, and prostate cancer. However, poor sensitivity been reported for non-small lung cancer (NSCLC). To address this problem, we developed a microcavity array (MCA) system integrated miniaturized device CTC isolation without relying on EpCAM expression. Here, report the results clinical study CTCs which compared...
Intrapancreatic accessory spleen (IPAS) is a mass that can mimick neoplastic in the pancreas. As it poses no clinical problem treatment required. Unfortunately almost all reported cases of IPAS have been misdiagnosed and unnecessary surgery performed. We performed contrast-enhanced ultrasound (CEUS) patient with for research purpose, confirmed CEUS useful diagnosing this entity.
Patients with nonvalvular atrial fibrillation (AF) not suitable for long-term anticoagulant therapy undergo percutaneous left appendage closure (LAAC) using the WATCHMAN device. The safety and efficacy of WATCHMAN-FLX (WM-FLX) compared WATCHMAN-2.5 (WM-2.5), particularly in Asian populations, is unknown.
Abstract Background Currently, no consensus has been established on the most effective antithrombotic therapy to prevent thromboembolic and bleeding events in patients undergoing percutaneous left atrial appendage closure (LAAC). Methods We retrospectively investigated incidence of device-related thrombosis (DRT), events, who underwent LAAC from September 2019 October 2022. After categorizing into groups based preprocedural or under oral anticoagulation (OAC) therapy, we compared DRT...
Little is known about the effects of left ventricular ejection fraction (LVEF) worsening after transcatheter edge-to-edge valve repair (TEER) for mitral regurgitation (MR).
ABSTRACT Background Research on the impact of angiographically detected residual trabeculation after left atrial appendage closure (LAAC) is limited. Objectives To investigate incidence, characteristics, and clinical implications LAAC using WATCHMAN device. Methods We analyzed 1350 consecutive patients with fibrillation undergoing device from OCEAN‐LAAC registry, which a prospective ongoing, multicenter Japanese registry. The inclusion criteria comprised who successfully underwent whose...
BACKGROUND: A small mitral valve area (MVA) is one of the challenging anatomies for transcatheter edge-to-edge repair (TEER) regurgitation, but relationship between baseline MVA and clinical outcomes remains unknown. This study aimed to evaluate association with procedural in patients undergoing TEER MitraClip from OCEAN-Mitral registry (Optimized Catheter Valvular Intervention-Mitral). METHODS: total 1768 were divided into 3 groups according MVA: group 1: <4.0 cm 2 , n=358; 2: 4.0–5.0...
Evidence is limited regarding long-term clinical outcomes after alcohol septal ablation (ASA) for patients with hypertrophic obstructive cardiomyopathy and its periprocedural predictive factors in Japan.
When we implant leadless pacemaker in patients with contrast agent allergy or poor renal function, the use of sufficient is hesitant. Aided by imaging assessment (e.g., intracardiac echocardiography), procedure may be feasible a small amount medium no medium. In this case, implantation was performed at same time as transcatheter mitral valve repair, and successful very under transesophageal echocardiography guidance.
Abstract Background: We have developed a microcavity array (MCA) system integrated with miniaturized device for the isolation of circulating tumor cells (CTC) without relying on EpCAM expression. The MCA allows filtration from whole blood basis differences in size between and cells. previous study has shown that is potentially superior to conventional epithelial antigen-based method detecting CTCs non-small cell lung cancer. Recently, we further optimized shape porosity efficiently isolate...