A5071736888- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Cardiomyopathy and Myosin Studies
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Arrhythmias and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Congenital Heart Disease Studies
- Pericarditis and Cardiac Tamponade
- Blood Pressure and Hypertension Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Viral Infections and Immunology Research
- Cardiac Ischemia and Reperfusion
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Health and Disease Prevention
National Cerebral and Cardiovascular Center
2016-2025
Cardiovascular Research Center
2022
Abbott (United States)
2018
Abbott Vascular (United States)
2018
Icahn School of Medicine at Mount Sinai
2013-2014
University of Trieste
2014
The University of Texas Health Science Center at San Antonio
2014
Mount Sinai Medical Center
2014
Mount Sinai Hospital
2013-2014
Should early surgery be conducted for asymptomatic patients with severe AR an LVEF ≥50% and LVESD index >25 mm/m 2 ?Early may considered .2 C CQ 3 operation very AS preserved LVEF?If the transvalvular peak velocity is ≥5.0 m/s, mean pressure gradient ≥60 mmHg, or AVA ≤0.6 cm , recommended at low surgical risk. B 4Should concomitant tricuspid valve repair mild TR annular dilation (>40 mm 21 in diameter)?Concomitant diameter). 5Can direct oral anticoaglants (DOACs) used AF after bioprosthetic...
Abstract Background and Aims The association between periprocedural change in tricuspid regurgitation (TR) outcomes patients undergoing mitral transcatheter edge-to-edge repair (M-TEER) is unclear. This study aimed to examine the prognostic value of TR before after M-TEER. Methods Patients OCEAN-Mitral registry were divided into four groups according baseline post-procedure echocardiographic assessments: no TR/no (no TR), TR/significant (new-onset significant (normalized (residual TR) (all...
<h3>Background</h3> Gadolinium-enhanced cardiovascular magnetic resonance is an emerging tool for the diagnosis of cardiac sarcoidosis (CS); however, correlations between extent late gadolinium enhancement (LGE) and efficacy steroid therapy adverse outcomes in patients with CS remain unclear. <h3>Objective</h3> We aimed to clarify prognostic impact LGE CS. <h3>Methods</h3> Before start therapy, 43 consecutive LGE-positive were divided into two groups based on by a median value: small-extent...
Background Limited data are available about clinical outcomes and residual mitral regurgitation (MR) after transcatheter edge-to-edge repair in the large Asian-Pacific cohort. Methods Results From Optimized Catheter Valvular Intervention (OCEAN-Mitral) registry, a total of 2150 patients (primary cause 34.6%) undergoing were analyzed classified into 3 groups according to MR severity at discharge: 0+/1+, 2+, 3+/4+. The mortality heart failure hospitalization rates 1 year 12.3% 15.0%,...
Renal impairment is associated with poor clinical outcomes in patients cardiovascular diseases. Some studies have revealed the impact of renal on who underwent mitral valve transcatheter edge-to-edge repair (M-TEER). However, limited data are available regarding baseline after M-TEER Asian-Pacific heart failure and severe regurgitation. This study sought to examine effect using a large-scale nationwide registry Japan. A total 2,150 enrolled OCEAN-Mitral (Optimized Catheter Valvular...
Background— Variations in longitudinal deformation of the left ventricle have been suggested to be useful for differentiating chronic constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). We assessed ventricular mechanics derived from cardiac magnetic resonance (CMR) cine–based 2-dimensional echocardiography–based tissue tracking determine intermodality consistency diagnostic information CP RCM. Methods Results— retrospectively identified 92 patients who underwent both CMR...
Abstract Aims Altered thyroid hormone metabolism characterized by a low triiodothyronine (T3), so‐called low‐T3 syndrome, is common finding in patients with severe systemic diseases. Additionally, subclinical dysfunction, defined as abnormal stimulating (TSH) and normal thyroxine (T4), causes left ventricular dysfunction. Our objective was to identify the prevalence prognostic impact of syndrome dysfunction acute decompensated heart failure (ADHF). Methods results We examined 274 ADHF who...
Transcatheter edge-to-edge repair (TEER) is a less invasive treatment for patients with mitral regurgitation (MR). Limited safety and efficacy data of TEER MitraClip, including the fourth-generation (G4) system, in large cohort, are available.This study aimed to summarize initial experience system MR from registry Japan.The OCEAN (Optimized CathEter vAlvular iNtervention)-Mitral Registry an ongoing, prospective, investigator-initiated, multicenter, observational primary secondary undergoing...
Abstract Background When determining the optimal timing of surgery for aortic regurgitation (AR), evaluation left ventricular contractile reserve (LVCR) using exercise stress echocardiography (ESE) is helpful. However, no previous studies have identified relationship between LVCR and low energy efficiency in ventricle during exercise. Purpose We assessed intraventricular flow dynamic parameters vector mapping (VFM) patients with chronic AR. Methods retrospectively enrolled 44 consecutive...
Right ventricular (RV) dysfunction negatively affects mitral valve transcatheter edge-to-edge repair (M-TEER) outcomes in patients with secondary regurgitation (vSMR). However, RV occurs the late phase of heart failure, when it may not respond to interventions. The pulsatile component afterload, pulmonary artery (PA) compliance, is a sensitive parameter that decreases before occurs. We explored utility PA compliance predicting cardiac events after M-TEER. analyzed 107 vSMR who underwent...
Background In patients with sarcoidosis, cardiac involvement is a crucial prognostic factor leading to severe cardiovascular events. Mitral regurgitation (MR) predisposes drug‐refractory heart failure; however, MR in sarcoidosis (CS) has been scarcely investigated and its therapeutic approach remains unclear. This study aimed investigate the clinical impact of transcatheter edge‐to‐edge repair CS. Methods Patients CS‐related ventricular functional were compared those other nonischemic...
Objective Atrial functional mitral regurgitation (A-FMR) has been suggested as a new aetiology of MR (MR); however, its prognosis and prognostic predictors are not fully elucidated. Aim this study was to investigate the A-FMR in comparison with ventricular (V-FMR). Methods Three hundred seventy-eight consecutive patients moderate-to-severe or severe were studied. Functional classified into V-FMR (N=288) (N=90) depending on alterations left ventricle (LV) atrium (LA) along clinical context...
Background:The MitraClip®system is a transcatheter-based therapeutic option for patients with chronic mitral regurgitation (MR) who are at high risk surgery. A prospective, multicenter, single-arm study was initiated to confirm the transferability of this system Japan.
Patients with heart failure (HF) have a high risk of cardiovascular (CV) death and re-hospitalization. The purpose the present study was therefore to investigate predictors CV re-hospitalization for acute decompensated HF (ADHF). A total 225 patients aged 67.2±15.2 years, including 134 men (59.6%), who were hospitalized ADHF between 2008 2009, followed up. After discharge, relationship clinical parameters events (ie, or HF) examined. Follow-up continued until 30 April 2011. most important...
The extent of cardiac damage and its association with clinical outcomes in patients undergoing transcatheter edge-to-edge repair (TEER) for degenerative mitral regurgitation remains unclear. This study was aimed to investigate treated TEER outcomes.