- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Cardiac tumors and thrombi
- Cardiac pacing and defibrillation studies
- Radiopharmaceutical Chemistry and Applications
- Neurobiology and Insect Physiology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Congenital Heart Disease Studies
- Vascular Procedures and Complications
- Invertebrate Immune Response Mechanisms
- Hormonal Regulation and Hypertension
- Coronary Artery Anomalies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Adrenal Hormones and Disorders
- Scoliosis diagnosis and treatment
- Insect Resistance and Genetics
Toyohashi Heart Center
2019-2024
The University of Tokyo
2024
Nagoya Heart Center
2023-2024
Shimane University
2016
Matsudo City Hospital
2015-2016
Background Limited data are available about clinical outcomes and residual mitral regurgitation (MR) after transcatheter edge-to-edge repair in the large Asian-Pacific cohort. Methods Results From Optimized Catheter Valvular Intervention (OCEAN-Mitral) registry, a total of 2150 patients (primary cause 34.6%) undergoing were analyzed classified into 3 groups according to MR severity at discharge: 0+/1+, 2+, 3+/4+. The mortality heart failure hospitalization rates 1 year 12.3% 15.0%,...
Transcatheter edge-to-edge repair (TEER) is a less invasive treatment for patients with mitral regurgitation (MR). Limited safety and efficacy data of TEER MitraClip, including the fourth-generation (G4) system, in large cohort, are available.This study aimed to summarize initial experience system MR from registry Japan.The OCEAN (Optimized CathEter vAlvular iNtervention)-Mitral Registry an ongoing, prospective, investigator-initiated, multicenter, observational primary secondary undergoing...
Diapause is a survival strategy in which growth and aging are temporarily suspended, enabling animals to withstand unfavorable environments. Various insects, including the fruit fly Drosophila , enter reproductive diapause, or dormancy, response cold temperatures and/or short-day lengths. During ovarian development halts, non-reproductive organs also undergo remodeling at both morphological metabolic levels: however, mechanisms underlying this its physiological impact remain largely unclear....
The extent of cardiac damage and its association with clinical outcomes in patients undergoing transcatheter edge-to-edge repair (TEER) for degenerative mitral regurgitation remains unclear. This study was aimed to investigate treated TEER outcomes.
Abstract Objectives Estimating 1‐year life expectancy is an essential factor when evaluating appropriate indicators for transcatheter aortic valve replacement (TAVR). Background It clinically useful in developing a reliable risk model predicting mortality after TAVR. Methods We evaluated 2,588 patients who underwent TAVR using data from the Optimized CathEter vAlvular iNtervention (OCEAN) Japanese multicenter registry October 2013 to May 2017. The clinical follow‐up was achieved by 99.5% of...
Data regarding the incidence, predictive factors, and clinical outcomes of post-transcatheter aortic valve replacement (TAVR) bleeding is limited in Asian cohort.This study sought to assess predictors prognostic impact post-TAVR late bleeding.This used Japanese multicenter registry data analyze 2,518 patients (mean age: 84.3 ± 5.2 years) who underwent TAVR. Late was defined as any postdischarge events after Baseline characteristics, including death rehospitalization were assessed with...
Abstract Aims This study investigated the prognostic value of plasma volume status (PVS) in patients who underwent transcatheter aortic valve replacement (TAVR). Methods and results Plasma was calculated 2588 TAVR using data from Japanese multicentre registry. All‐cause mortality heart failure hospitalization (HFH) within 2 years were compared among PVS quartiles (Q1, < 5.5%; Q2, 5.5–13.5%; Q3, 13.5–21.0%; Q4, ≥ 21.0%). Subgroups stratified by cut‐off combined with New York Heart...
The aim of this study was to identify the predictive factors for suboptimal result in side branch (SB) chronic total occlusion (CTO) bifurcation lesions and clinical outcomes patients with SB.
A 76-year-old woman was hospitalized repeatedly due to unexplained heart failure. On admission, she had hypertensive acute Her symptoms disappeared promptly after the initial treatment; however, her systolic blood pressure remained at over 160 mmHg despite taking three antihypertensive drugs. Closer examination revealed hemodynamically significant right renal artery stenosis and a lack of left kidney function. We performed percutaneous transluminal angioplasty using CO2 angiography in...
Background Ventricular‐arterial coupling predicts outcomes in patients with heart failure. The arterial elastance to end‐systolic ratio (Ea/Ees) is a noninvasively assessed index that reflects ventricular‐arterial coupling. We aimed determine the prognostic value of through Ea/Ees after transcatheter aortic valve replacement predict clinical events. Methods and Results retrieved data on 1378 (70% women) who underwent between October 2013 May 2017 from OCEAN‐TAVI (Optimized transCathEter...
Whether nerve block improves the quality of conscious sedation (CS) in patients undergoing transcatheter aortic valve implantation (TAVI) is unclear. This study investigated whether fascia iliaca (FIB) reduced remifentanil requirement and relieved pain CS for TAVI.
Abstract Background The remarkable regenerative abilities observed in planarians and cnidarians are closely linked to the active proliferation of adult stem cells precise differentiation their progeny, both which typically deteriorate during aging low animals. While regeneration-specific genes conserved highly organisms may confer long-term maintenance tissue homeostasis, it remains unclear whether introducing these into animals can improve regeneration processes. Results Here, we...
Malperfusion syndrome is a complication of acute aortic dissection (AAD) involving branch vessel. We report case bailout stenting for critical cerebral malperfusion in patient with AAD after transcatheter valve replacement. Rescue percutaneous procedure this may be treatment option patients high surgical risk. (Level Difficulty: Advanced.).
Although Arm circumference (AC) is considered to be a predictor of clinical outcomes transcatheter aortic valve replacement (TAVR), limited data are available on the impact this anthropometric measurement. This study aimed investigate AC patients who underwent TAVR.AC was investigated in consecutive TAVR between March 2014 and May 2018. Patients were divided into low (n = 220) high 127) groups by classification regression tree (CART) survival model, their baseline characteristics mortality...
A 54-year-old woman was hospitalized in 1989 because of palpitations. She had a family history hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy diagnosed by two-dimensional echocardiography, cardiac catheterization, and myocardial biopsy. coronary arteriogram disclosed normal arteries. received diltiazem meliletine for 9 years. Her functional class, the New York Heart Association classification, worsened from II to III since 1995. Two-dimensional echocardiography showed thrombus left...
Abstract Background For recanalization of coronary chronic total occlusion (CTO) lesions, subintimal guidewire tracking in both antegrade and retrograde approaches are commonly used. Purpose This study aimed to assess the impact on long-term clinical outcomes after CTO lesions. Methods Between January 2009 December 2016, 474 lesions (434patients) were successfully recanalized our center. After crossing a lesion, those divided into intimal group (84.6%, n=401) (15.4%, n=73) according...